WILMINGTON, DE
PRELUDE THERAPEUTICS INCPRLD— Latest position per institution from SEC 13F filings
15
Institutional holders
58.70M
Total shares held
276.49M
Estimated value
2.94M
Avg. position size
ORBIMED ADVISORS LLC
CIK 1055951
Shares
13.72M
Value
73.15M
Filed
Jun 30, 2026
BAKER BROS. ADVISORS LP
CIK 1263508
Shares
10.12M
Value
53.96M
Filed
Jun 30, 2026
RA CAPITAL MANAGEMENT, L.P.
CIK 1346824
Shares
6.48M
Value
34.52M
Filed
Jun 30, 2026
DEERFIELD MANAGEMENT COMPANY, L.P.
CIK 1009258
Shares
3.77M
Value
7.80M
Filed
Sep 30, 2024
SOLEUS CAPITAL MANAGEMENT, L.P.
CIK 1802630
Shares
3.38M
Value
18.01M
Filed
Jun 30, 2026
KYNAM CAPITAL MANAGEMENT, LP
CIK 1907884
Shares
2.42M
Value
12.87M
Filed
Jun 30, 2026
UBS AM, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS LLC
CIK 861177
Shares
2.27M
Value
12.96M
Filed
Jun 30, 2023
BOXER CAPITAL MANAGEMENT, LLC
CIK 2018299
Shares
2.11M
Value
1.62M
Filed
Mar 31, 2025
VANGUARD CAPITAL MANAGEMENT LLC
CIK 2100119
Shares
2.01M
Value
10.71M
Filed
Jun 30, 2026
BLACKROCK, INC.
CIK 2012383
Shares
1.80M
Value
9.58M
Filed
Jun 30, 2026
BOXER CAPITAL, LLC
CIK 1465837
Shares
1.71M
Value
3.54M
Filed
Sep 30, 2024
VANGUARD GROUP INC
CIK 102909
Shares
1.41M
Value
4.10M
Filed
Dec 31, 2025
BLACKROCK FINANCE, INC.
CIK 1364742
Shares
1.07M
Value
4.07M
Filed
Jun 30, 2024
SPHERA FUNDS MANAGEMENT LTD.
CIK 1496201
Shares
1.02M
Value
5.44M
Filed
Jun 30, 2026
TWO SIGMA INVESTMENTS, LP
CIK 1179392
Shares
993.37K
Value
5.29M
Filed
Jun 30, 2026
ECOR1 CAPITAL, LLC
CIK 1587114
Shares
947.05K
Value
3.24M
Filed
Mar 31, 2026
ADAR1 CAPITAL MANAGEMENT, LLC
CIK 1940272
Shares
900.90K
Value
4.80M
Filed
Jun 30, 2026
AVIDITY PARTNERS MANAGEMENT LP
CIK 1791827
Shares
890K
Value
1.84M
Filed
Sep 30, 2024
MILLENNIUM MANAGEMENT LLC
CIK 1273087
Shares
844.99K
Value
4.50M
Filed
Jun 30, 2026
GEODE CAPITAL MANAGEMENT, LLC
CIK 1214717
Shares
841.86K
Value
4.49M
Filed
Jun 30, 2026
| # | Institution | CIK | Shares | Est. Value | Period |
|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 1055951 | 13.72M | 73.15M | Jun 30, 2026 |
| 2 | BAKER BROS. ADVISORS LP | 1263508 | 10.12M | 53.96M | Jun 30, 2026 |
| 3 | RA CAPITAL MANAGEMENT, L.P. | 1346824 | 6.48M | 34.52M | Jun 30, 2026 |
| 4 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1009258 | 3.77M | 7.80M | Sep 30, 2024 |
| 5 | SOLEUS CAPITAL MANAGEMENT, L.P. | 1802630 | 3.38M | 18.01M | Jun 30, 2026 |
| 6 | KYNAM CAPITAL MANAGEMENT, LP | 1907884 | 2.42M | 12.87M | Jun 30, 2026 |
| 7 | UBS AM, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS LLC | 861177 | 2.27M | 12.96M | Jun 30, 2023 |
| 8 | BOXER CAPITAL MANAGEMENT, LLC | 2018299 | 2.11M | 1.62M | Mar 31, 2025 |
| 9 | VANGUARD CAPITAL MANAGEMENT LLC | 2100119 | 2.01M | 10.71M | Jun 30, 2026 |
| 10 | BLACKROCK, INC. | 2012383 | 1.80M | 9.58M | Jun 30, 2026 |
| 11 | BOXER CAPITAL, LLC | 1465837 | 1.71M | 3.54M | Sep 30, 2024 |
| 12 | VANGUARD GROUP INC | 102909 | 1.41M | 4.10M | Dec 31, 2025 |
| 13 | BLACKROCK FINANCE, INC. | 1364742 | 1.07M | 4.07M | Jun 30, 2024 |
| 14 | SPHERA FUNDS MANAGEMENT LTD. | 1496201 | 1.02M | 5.44M | Jun 30, 2026 |
| 15 | TWO SIGMA INVESTMENTS, LP | 1179392 | 993.37K | 5.29M | Jun 30, 2026 |
| 16 | ECOR1 CAPITAL, LLC | 1587114 | 947.05K | 3.24M | Mar 31, 2026 |
| 17 | ADAR1 CAPITAL MANAGEMENT, LLC | 1940272 | 900.90K | 4.80M | Jun 30, 2026 |
| 18 | AVIDITY PARTNERS MANAGEMENT LP | 1791827 | 890K | 1.84M | Sep 30, 2024 |
| 19 | MILLENNIUM MANAGEMENT LLC | 1273087 | 844.99K | 4.50M | Jun 30, 2026 |
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 1214717 | 841.86K | 4.49M | Jun 30, 2026 |
Data sourced from SEC Form 13F institutional holdings reports. Positions reflect the most recent filing per institution.