PRELUDE THERAPEUTICS INC

PublicCIK: 1678660

PRLDNASDAQ

Location

WILMINGTON, DE

BAKER BROS. ADVISORS LP

→MADRIGAL PHARMACEUTICALS, INC.

Jun 18, 2026·2d ago

4 txn

ORBIMED ADVISORS LLC

→ENLIVEN THERAPEUTICS, INC.

Jun 17, 2026·3d ago

2 txn

HUANG JANE

→PROTARA THERAPEUTICS, INC.

Jun 16, 2026·5d ago

1 txn

RA CAPITAL MANAGEMENT, L.P.

→NKARTA, INC.

Jun 11, 2026·Jun 11, 2026

1 txn

BAKER BROS. ADVISORS LP

→PRELUDE THERAPEUTICS INC

Jun 10, 2026·Jun 10, 2026

2 txn

DORTON KATINA

→PRELUDE THERAPEUTICS INC

Jun 10, 2026·Jun 10, 2026

1 txn

BONITA DAVID P

→PRELUDE THERAPEUTICS INC

Jun 10, 2026·Jun 10, 2026

1 txn

SANDOR VICTOR

→PRELUDE THERAPEUTICS INC

Jun 10, 2026·Jun 10, 2026

1 txn

FRIEDMAN PAUL A

→PRELUDE THERAPEUTICS INC

Jun 10, 2026·Jun 10, 2026

1 txn

BAKER BROS. ADVISORS LP

→INCYTE CORP

Jun 10, 2026·Jun 10, 2026

7 txn

BABLER MARTIN

→PRELUDE THERAPEUTICS INC

Jun 10, 2026·Jun 10, 2026

1 txn

DORTON KATINA

→KEENOVA THERAPEUTICS PLC

Jun 4, 2026·Jun 4, 2026

2 txn

BAKER BROS. ADVISORS LP

→ACADIA PHARMACEUTICALS INC

Jun 2, 2026·Jun 2, 2026

6 txn

ORBIMED ADVISORS LLC

→Q32 BIO INC.

Jun 2, 2026·Jun 2, 2026

2 txn

BAKER BROS. ADVISORS LP

→KINIKSA PHARMACEUTICALS INTERNATIONAL, PLC

Jun 2, 2026·Jun 2, 2026

6 txn

BAKER BROS. ADVISORS LP

13F-HR

Holdings

May 15, 2026·May 15, 2026

RA CAPITAL MANAGEMENT, L.P.

13F-HR

Holdings

May 15, 2026·May 15, 2026

ORBIMED ADVISORS LLC

13F-HR

Holdings

May 15, 2026·May 15, 2026

BAKER BROS. ADVISORS LP

→INCYTE CORP

May 11, 2026·May 11, 2026

7 txn

MORRIS CHARLES Q

→PRELUDE THERAPEUTICS INC

May 4, 2026·May 4, 2026

1 txn

RA CAPITAL MANAGEMENT, L.P.

→PRELUDE THERAPEUTICS INC

Apr 28, 2026·Apr 28, 2026

2 txn

RA CAPITAL MANAGEMENT, L.P.

→PRELUDE THERAPEUTICS INC

Apr 28, 2026·Apr 28, 2026

1 txn

BAKER BROTHERS LIFE SCIENCES LP

144

→PROTARA THERAPEUTICS, INC.

Apr 24, 2026·Apr 24, 2026

-5

667, L.P.

144

→PROTARA THERAPEUTICS, INC.

Apr 24, 2026·Apr 24, 2026

-5

BONITA DAVID P

→PRELUDE THERAPEUTICS INC

Apr 23, 2026·Apr 23, 2026

3 txn

Page 1 of 41 · 1,020 total

Filer	Form	Target	Filed	Activity
BAKER BROS. ADVISORS LPCIK · 1263508	4 Trade	MADRIGAL PHARMACEUTICALS, INC.CIK · 1157601	Jun 18, 2026 2d ago	4txn
ORBIMED ADVISORS LLCCIK · 1055951	4 Trade	ENLIVEN THERAPEUTICS, INC.CIK · 1672619	Jun 17, 2026 3d ago	2txn
HUANG JANECIK · 1683913	4 Trade	PROTARA THERAPEUTICS, INC.CIK · 1359931	Jun 16, 2026 5d ago	1txn
RA CAPITAL MANAGEMENT, L.P.CIK · 1346824	4 Trade	NKARTA, INC.CIK · 1787400	Jun 11, 2026 Jun 11, 2026	1txn
BAKER BROS. ADVISORS LPCIK · 1263508	4 Trade	PRELUDE THERAPEUTICS INCCIK · 1678660	Jun 10, 2026 Jun 10, 2026	2txn
DORTON KATINACIK · 1617541	4 Trade	PRELUDE THERAPEUTICS INCCIK · 1678660	Jun 10, 2026 Jun 10, 2026	1txn
BONITA DAVID PCIK · 1572451	4 Trade	PRELUDE THERAPEUTICS INCCIK · 1678660	Jun 10, 2026 Jun 10, 2026	1txn
SANDOR VICTORCIK · 1620368	4 Trade	PRELUDE THERAPEUTICS INCCIK · 1678660	Jun 10, 2026 Jun 10, 2026	1txn
FRIEDMAN PAUL ACIK · 1236927	4 Trade	PRELUDE THERAPEUTICS INCCIK · 1678660	Jun 10, 2026 Jun 10, 2026	1txn
BAKER BROS. ADVISORS LPCIK · 1263508	4 Trade	INCYTE CORPCIK · 879169	Jun 10, 2026 Jun 10, 2026	7txn
BABLER MARTINCIK · 1435618	4 Trade	PRELUDE THERAPEUTICS INCCIK · 1678660	Jun 10, 2026 Jun 10, 2026	1txn
DORTON KATINACIK · 1617541	4 Trade	KEENOVA THERAPEUTICS PLCCIK · 1567892	Jun 4, 2026 Jun 4, 2026	2txn
BAKER BROS. ADVISORS LPCIK · 1263508	4 Trade	ACADIA PHARMACEUTICALS INCCIK · 1070494	Jun 2, 2026 Jun 2, 2026	6txn
ORBIMED ADVISORS LLCCIK · 1055951	4 Trade	Q32 BIO INC.CIK · 1661998	Jun 2, 2026 Jun 2, 2026	2txn
BAKER BROS. ADVISORS LPCIK · 1263508	4 Trade	KINIKSA PHARMACEUTICALS INTERNATIONAL, PLCCIK · 1730430	Jun 2, 2026 Jun 2, 2026	6txn
BAKER BROS. ADVISORS LPCIK · 1263508	13F-HR Holdings	—	May 15, 2026 May 15, 2026	—
RA CAPITAL MANAGEMENT, L.P.CIK · 1346824	13F-HR Holdings	—	May 15, 2026 May 15, 2026	—
ORBIMED ADVISORS LLCCIK · 1055951	13F-HR Holdings	—	May 15, 2026 May 15, 2026	—
BAKER BROS. ADVISORS LPCIK · 1263508	4 Trade	INCYTE CORPCIK · 879169	May 11, 2026 May 11, 2026	7txn
MORRIS CHARLES QCIK · 1489966	4 Trade	PRELUDE THERAPEUTICS INCCIK · 1678660	May 4, 2026 May 4, 2026	1txn
RA CAPITAL MANAGEMENT, L.P.CIK · 1346824	4 Trade	PRELUDE THERAPEUTICS INCCIK · 1678660	Apr 28, 2026 Apr 28, 2026	2txn
RA CAPITAL MANAGEMENT, L.P.CIK · 1346824	3 Initial	PRELUDE THERAPEUTICS INCCIK · 1678660	Apr 28, 2026 Apr 28, 2026	1txn
BAKER BROTHERS LIFE SCIENCES LPCIK · 1363364	144 Sale	PROTARA THERAPEUTICS, INC.CIK · 1359931	Apr 24, 2026 Apr 24, 2026	—
667, L.P.CIK · 1551139	144 Sale	PROTARA THERAPEUTICS, INC.CIK · 1359931	Apr 24, 2026 Apr 24, 2026	—
BONITA DAVID PCIK · 1572451	4 Trade	PRELUDE THERAPEUTICS INCCIK · 1678660	Apr 23, 2026 Apr 23, 2026	3txn

Page 1 of 41 · 1,020 total