WINCHESTER, MA
SYNLOGIC, INC.SYBX— Latest position per institution from SEC 13F filings
15
Institutional holders
8.67M
Total shares held
13.94M
Estimated value
433.71K
Avg. position size
CABLE CAR CAPITAL, LP
CIK 1699575
Shares
3.31M
Value
3.71M
Filed
Dec 31, 2025
NEA MANAGEMENT COMPANY, LLC
CIK 1512848
Shares
2.92M
Value
3.27M
Filed
Dec 31, 2025
ARMISTICE CAPITAL, LLC
CIK 1601086
Shares
1.05M
Value
4.06M
Filed
Dec 31, 2023
ORBIMED ADVISORS LLC
CIK 1055951
Shares
402K
Value
1.13M
Filed
Sep 30, 2023
VANGUARD GROUP INC
CIK 102909
Shares
201.06K
Value
225.19K
Filed
Dec 31, 2025
ATLAS VENTURE ASSOCIATES IX, LLC
CIK 1671207
Shares
176.80K
Value
496.80K
Filed
Sep 30, 2023
CITADEL ADVISORS LLC
CIK 1423053
Shares
141.61K
Value
158.60K
Filed
Dec 31, 2025
RENAISSANCE TECHNOLOGIES LLC
CIK 1037389
Shares
85.63K
Value
95.90K
Filed
Dec 31, 2025
GEODE CAPITAL MANAGEMENT, LLC
CIK 1214717
Shares
71.64K
Value
80.25K
Filed
Dec 31, 2025
ALYESKA INVESTMENT GROUP, L.P.
CIK 1453072
Shares
55.87K
Value
215.11K
Filed
Dec 31, 2023
OCONNOR, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS (LLC)
CIK 1132716
Shares
40.55K
Value
113.94K
Filed
Sep 30, 2023
SOFINNOVA INVESTMENTS, INC.
CIK 1631134
Shares
38.33K
Value
107.71K
Filed
Sep 30, 2023
HARBOR CAPITAL ADVISORS, INC.
CIK 1039128
Shares
30.68K
Value
118.14K
Filed
Dec 31, 2023
DRW SECURITIES, LLC
CIK 1481986
Shares
23.76K
Value
16.66K
Filed
Jun 30, 2026
FIDUCIARY TRUST CO
CIK 35442
Shares
22.35K
Value
28.39K
Filed
Jun 30, 2025
IKARIAN CAPITAL, LLC
CIK 1778253
Shares
19.97K
Value
22.36K
Filed
Dec 31, 2025
BLACKROCK FINANCE, INC.
CIK 1364742
Shares
19.76K
Value
29.64K
Filed
Jun 30, 2024
BLACKROCK, INC.
CIK 2012383
Shares
19.76K
Value
22.13K
Filed
Dec 31, 2025
NORTHERN TRUST CORP
CIK 73124
Shares
19.47K
Value
21.80K
Filed
Dec 31, 2025
JANE STREET GROUP, LLC
CIK 1595888
Shares
15K
Value
16.80K
Filed
Dec 31, 2025
| # | Institution | CIK | Shares | Est. Value | Period |
|---|---|---|---|---|---|
| 1 | CABLE CAR CAPITAL, LP | 1699575 | 3.31M | 3.71M | Dec 31, 2025 |
| 2 | NEA MANAGEMENT COMPANY, LLC | 1512848 | 2.92M | 3.27M | Dec 31, 2025 |
| 3 | ARMISTICE CAPITAL, LLC | 1601086 | 1.05M | 4.06M | Dec 31, 2023 |
| 4 | ORBIMED ADVISORS LLC | 1055951 | 402K | 1.13M | Sep 30, 2023 |
| 5 | VANGUARD GROUP INC | 102909 | 201.06K | 225.19K | Dec 31, 2025 |
| 6 | ATLAS VENTURE ASSOCIATES IX, LLC | 1671207 | 176.80K | 496.80K | Sep 30, 2023 |
| 7 | CITADEL ADVISORS LLC | 1423053 | 141.61K | 158.60K | Dec 31, 2025 |
| 8 | RENAISSANCE TECHNOLOGIES LLC | 1037389 | 85.63K | 95.90K | Dec 31, 2025 |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 1214717 | 71.64K | 80.25K | Dec 31, 2025 |
| 10 | ALYESKA INVESTMENT GROUP, L.P. | 1453072 | 55.87K | 215.11K | Dec 31, 2023 |
| 11 | OCONNOR, A DISTINCT BUSINESS UNIT OF UBS ASSET MANAGEMENT AMERICAS (LLC) | 1132716 | 40.55K | 113.94K | Sep 30, 2023 |
| 12 | SOFINNOVA INVESTMENTS, INC. | 1631134 | 38.33K | 107.71K | Sep 30, 2023 |
| 13 | HARBOR CAPITAL ADVISORS, INC. | 1039128 | 30.68K | 118.14K | Dec 31, 2023 |
| 14 | DRW SECURITIES, LLC | 1481986 | 23.76K | 16.66K | Jun 30, 2026 |
| 15 | FIDUCIARY TRUST CO | 35442 | 22.35K | 28.39K | Jun 30, 2025 |
| 16 | IKARIAN CAPITAL, LLC | 1778253 | 19.97K | 22.36K | Dec 31, 2025 |
| 17 | BLACKROCK FINANCE, INC. | 1364742 | 19.76K | 29.64K | Jun 30, 2024 |
| 18 | BLACKROCK, INC. | 2012383 | 19.76K | 22.13K | Dec 31, 2025 |
| 19 | NORTHERN TRUST CORP | 73124 | 19.47K | 21.80K | Dec 31, 2025 |
| 20 | JANE STREET GROUP, LLC | 1595888 | 15K | 16.80K | Dec 31, 2025 |
Data sourced from SEC Form 13F institutional holdings reports. Positions reflect the most recent filing per institution.