Filed: 5/15/2026ACC: 0001104659-26-062256
📋 What this filing means
SOFINNOVA INVESTMENTS, INC. filed this quarterly 13F‑HR report disclosing 69 equity positions with a total reported market value of $2.63B. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
69
Positions
$2.63B
Total AUM (reported)
48.72M
Total Shares
Allocation by class
COM$1.67B63.6%
RUSSELL 2000 ETF$148.80M5.7%
STATE STREET SPD$134.12M5.1%
SHS USD$113.11M4.3%
CL A$112.40M4.3%
ORD$89.94M3.4%
UNIT SER 1$86.58M3.3%
Portfolio Concentration
Top 3$601.38M22.9%
4–10$738.11M28.1%
11–25$799.34M30.4%
Rest$492.32M18.7%
Top 3 weight
22.9%
Top 10 weight
50.9%
Voting Authority Distribution
Total shares with voting rights: 48.72M
Sole
Full voting authority
48.72M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole69
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings69
Rows:
Natera Inc
SOLEShares1.55M
TypeSH
Market value$310.04M
11.78%
Sole
1.55M
Shared
0.00
None
0.00
iShares TR
SOLEShares600K
TypeSH
Market value$148.80M
5.66%
Sole
600K
Shared
0.00
None
0.00
United Therapeutics Corp
SOLEShares240.37K
TypeSH
Market value$142.53M
5.42%
Sole
240.37K
Shared
0.00
None
0.00
SPDR Series Trust
SOLEShares1.05M
TypeSH
Market value$134.12M
5.10%
Sole
1.05M
Shared
0.00
None
0.00
Bristol-Myers Squibb Co
SOLEShares1.99M
TypeSH
Market value$120.62M
4.58%
Sole
1.99M
Shared
0.00
None
0.00
Jazz Pharmaceuticals PLC
SOLEShares598.33K
TypeSH
Market value$113.11M
4.30%
Sole
598.33K
Shared
0.00
None
0.00
Vera Therapeutics Inc
SOLEShares2.79M
TypeSH
Market value$112.40M
4.27%
Sole
2.79M
Shared
0.00
None
0.00
AstraZeneca PLC
SOLEShares456.03K
TypeSH
Market value$89.94M
3.42%
Sole
456.03K
Shared
0.00
None
0.00
Invesco QQQ TR
SOLEShares150K
TypeSH
Market value$86.58M
3.29%
Sole
150K
Shared
0.00
None
0.00
Cogent Biosciences Inc
SOLEShares2.11M
TypeSH
Market value$81.35M
3.09%
Sole
2.11M
Shared
0.00
None
0.00
iShares TR
SOLEShares475K
TypeSH
Market value$80.20M
3.05%
Sole
475K
Shared
0.00
None
0.00
Celcuity Inc
SOLEShares666.17K
TypeSH
Market value$76.04M
2.89%
Sole
666.17K
Shared
0.00
None
0.00
Ultragenyx Pharmaceutical Inc
SOLEShares3.50M
TypeSH
Market value$73.24M
2.78%
Sole
3.50M
Shared
0.00
None
0.00
Axsome Therapeutics Inc.
SOLEShares412.75K
TypeSH
Market value$69.76M
2.65%
Sole
412.75K
Shared
0.00
None
0.00
Rapport Therapeutics Inc
SOLEShares1.90M
TypeSH
Market value$59.59M
2.26%
Sole
1.90M
Shared
0.00
None
0.00
Insmed Inc
SOLEShares346.07K
TypeSH
Market value$56.59M
2.15%
Sole
346.07K
Shared
0.00
None
0.00
Alcon AG
SOLEShares729.97K
TypeSH
Market value$55.00M
2.09%
Sole
729.97K
Shared
0.00
None
0.00
Supernus Pharmaceuticals
SOLEShares954.31K
TypeSH
Market value$49.33M
1.87%
Sole
954.31K
Shared
0.00
None
0.00
BioMarin Pharmaceutical Inc
SOLEShares781.98K
TypeSH
Market value$44.17M
1.68%
Sole
781.98K
Shared
0.00
None
0.00
Biogen Inc
SOLEShares229.52K
TypeSH
Market value$42.08M
1.60%
Sole
229.52K
Shared
0.00
None
0.00
BioAge Labs Inc
SOLEShares2.29M
TypeSH
Market value$40.12M
1.52%
Sole
2.29M
Shared
0.00
None
0.00
Rhythm Pharmaceuticals Inc
SOLEShares450.10K
TypeSH
Market value$39.14M
1.49%
Sole
450.10K
Shared
0.00
None
0.00
Arrivent BioPharma Inc
SOLEShares1.70M
TypeSH
Market value$39.14M
1.49%
Sole
1.70M
Shared
0.00
None
0.00
IDEAYA Biosciences Inc
SOLEShares1.13M
TypeSH
Market value$37.71M
1.43%
Sole
1.13M
Shared
0.00
None
0.00
Immunome Inc
SOLEShares1.70M
TypeSH
Market value$37.22M
1.41%
Sole
1.70M
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
Natera IncSOLE | COM | 1.55M | SH | $310.04M 11.78% | 1.55M | 0.00 | 0.00 |
iShares TRSOLE | RUSSELL 2000 ETF | 600K | SH | $148.80M 5.66% | 600K | 0.00 | 0.00 |
United Therapeutics CorpSOLE | COM | 240.37K | SH | $142.53M 5.42% | 240.37K | 0.00 | 0.00 |
SPDR Series TrustSOLE | STATE STREET SPD | 1.05M | SH | $134.12M 5.10% | 1.05M | 0.00 | 0.00 |
Bristol-Myers Squibb CoSOLE | COM | 1.99M | SH | $120.62M 4.58% | 1.99M | 0.00 | 0.00 |
Jazz Pharmaceuticals PLCSOLE | SHS USD | 598.33K | SH | $113.11M 4.30% | 598.33K | 0.00 | 0.00 |
Vera Therapeutics IncSOLE | CL A | 2.79M | SH | $112.40M 4.27% | 2.79M | 0.00 | 0.00 |
AstraZeneca PLCSOLE | ORD | 456.03K | SH | $89.94M 3.42% | 456.03K | 0.00 | 0.00 |
Invesco QQQ TRSOLE | UNIT SER 1 | 150K | SH | $86.58M 3.29% | 150K | 0.00 | 0.00 |
Cogent Biosciences IncSOLE | COM | 2.11M | SH | $81.35M 3.09% | 2.11M | 0.00 | 0.00 |
iShares TRSOLE | ISHARES BIOTECH | 475K | SH | $80.20M 3.05% | 475K | 0.00 | 0.00 |
Celcuity IncSOLE | COM | 666.17K | SH | $76.04M 2.89% | 666.17K | 0.00 | 0.00 |
Ultragenyx Pharmaceutical IncSOLE | COM | 3.50M | SH | $73.24M 2.78% | 3.50M | 0.00 | 0.00 |
Axsome Therapeutics Inc.SOLE | COM | 412.75K | SH | $69.76M 2.65% | 412.75K | 0.00 | 0.00 |
Rapport Therapeutics IncSOLE | COM | 1.90M | SH | $59.59M 2.26% | 1.90M | 0.00 | 0.00 |
Insmed IncSOLE | COM PAR $.01 | 346.07K | SH | $56.59M 2.15% | 346.07K | 0.00 | 0.00 |
Alcon AGSOLE | ORD SHS | 729.97K | SH | $55.00M 2.09% | 729.97K | 0.00 | 0.00 |
Supernus PharmaceuticalsSOLE | COM | 954.31K | SH | $49.33M 1.87% | 954.31K | 0.00 | 0.00 |
BioMarin Pharmaceutical IncSOLE | COM | 781.98K | SH | $44.17M 1.68% | 781.98K | 0.00 | 0.00 |
Biogen IncSOLE | COM | 229.52K | SH | $42.08M 1.60% | 229.52K | 0.00 | 0.00 |
BioAge Labs IncSOLE | COM | 2.29M | SH | $40.12M 1.52% | 2.29M | 0.00 | 0.00 |
Rhythm Pharmaceuticals IncSOLE | COM | 450.10K | SH | $39.14M 1.49% | 450.10K | 0.00 | 0.00 |
Arrivent BioPharma IncSOLE | COM | 1.70M | SH | $39.14M 1.49% | 1.70M | 0.00 | 0.00 |
IDEAYA Biosciences IncSOLE | COM | 1.13M | SH | $37.71M 1.43% | 1.13M | 0.00 | 0.00 |
Immunome IncSOLE | COM | 1.70M | SH | $37.22M 1.41% | 1.70M | 0.00 | 0.00 |
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