ROCKVILLE, MD
OS THERAPIES INCOSTX— Latest position per institution from SEC 13F filings
15
Institutional holders
3.43M
Total shares held
5.93M
Estimated value
171.46K
Avg. position size
VANGUARD CAPITAL MANAGEMENT LLC
CIK 2100119
Shares
777.65K
Value
1.48M
Filed
Jun 30, 2026
VANGUARD GROUP INC
CIK 102909
Shares
540.42K
Value
756.59K
Filed
Dec 31, 2025
CM MANAGEMENT, LLC
CIK 1841857
Shares
400K
Value
760K
Filed
Jun 30, 2026
GEODE CAPITAL MANAGEMENT, LLC
CIK 1214717
Shares
301.79K
Value
573.41K
Filed
Jun 30, 2026
HOWARD FINANCIAL SERVICES, LTD.
CIK 1768130
Shares
248K
Value
396.80K
Filed
Sep 30, 2026
BLACKROCK, INC.
CIK 2012383
Shares
242.48K
Value
460.71K
Filed
Jun 30, 2026
VANGUARD FIDUCIARY TRUST CO
CIK 933478
Shares
174.13K
Value
330.85K
Filed
Jun 30, 2026
STATE STREET CORP
CIK 93751
Shares
120.10K
Value
228.19K
Filed
Jun 30, 2026
MARSHALL WACE, LLP
CIK 1318757
Shares
100.64K
Value
191.22K
Filed
Jun 30, 2026
HIGHTOWER ADVISORS, LLC
CIK 1462245
Shares
85.55K
Value
162.54K
Filed
Jun 30, 2026
VIRTU FINANCIAL LLC
CIK 1533964
Shares
75.80K
Value
149.00
Filed
Sep 30, 2025
NORTHERN TRUST CORP
CIK 73124
Shares
70.82K
Value
134.55K
Filed
Jun 30, 2026
BEACON POINTE ADVISORS, LLC
CIK 1744317
Shares
62.51K
Value
118.76K
Filed
Jun 30, 2026
BRIDGEWAY CAPITAL MANAGEMENT, LLC
CIK 1107261
Shares
45K
Value
85.50K
Filed
Jun 30, 2026
INGALLS & SNYDER LLC
CIK 1041885
Shares
36.68K
Value
70.00
Filed
Jun 30, 2026
XTX TOPCO LTD
CIK 1828301
Shares
31.62K
Value
44.59K
Filed
Mar 31, 2026
MILLENNIUM MANAGEMENT LLC
CIK 1273087
Shares
30.79K
Value
43.10K
Filed
Dec 31, 2025
TWO SIGMA INVESTMENTS, LP
CIK 1179392
Shares
30.41K
Value
57.79K
Filed
Jun 30, 2026
STIFEL FINANCIAL CORP
CIK 720672
Shares
27.90K
Value
53.01K
Filed
Jun 30, 2026
JANE STREET GROUP, LLC
CIK 1595888
Shares
27K
Value
51.30K
Filed
Jun 30, 2026
| # | Institution | CIK | Shares | Est. Value | Period |
|---|---|---|---|---|---|
| 1 | VANGUARD CAPITAL MANAGEMENT LLC | 2100119 | 777.65K | 1.48M | Jun 30, 2026 |
| 2 | VANGUARD GROUP INC | 102909 | 540.42K | 756.59K | Dec 31, 2025 |
| 3 | CM MANAGEMENT, LLC | 1841857 | 400K | 760K | Jun 30, 2026 |
| 4 | GEODE CAPITAL MANAGEMENT, LLC | 1214717 | 301.79K | 573.41K | Jun 30, 2026 |
| 5 | HOWARD FINANCIAL SERVICES, LTD. | 1768130 | 248K | 396.80K | Sep 30, 2026 |
| 6 | BLACKROCK, INC. | 2012383 | 242.48K | 460.71K | Jun 30, 2026 |
| 7 | VANGUARD FIDUCIARY TRUST CO | 933478 | 174.13K | 330.85K | Jun 30, 2026 |
| 8 | STATE STREET CORP | 93751 | 120.10K | 228.19K | Jun 30, 2026 |
| 9 | MARSHALL WACE, LLP | 1318757 | 100.64K | 191.22K | Jun 30, 2026 |
| 10 | HIGHTOWER ADVISORS, LLC | 1462245 | 85.55K | 162.54K | Jun 30, 2026 |
| 11 | VIRTU FINANCIAL LLC | 1533964 | 75.80K | 149.00 | Sep 30, 2025 |
| 12 | NORTHERN TRUST CORP | 73124 | 70.82K | 134.55K | Jun 30, 2026 |
| 13 | BEACON POINTE ADVISORS, LLC | 1744317 | 62.51K | 118.76K | Jun 30, 2026 |
| 14 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 1107261 | 45K | 85.50K | Jun 30, 2026 |
| 15 | INGALLS & SNYDER LLC | 1041885 | 36.68K | 70.00 | Jun 30, 2026 |
| 16 | XTX TOPCO LTD | 1828301 | 31.62K | 44.59K | Mar 31, 2026 |
| 17 | MILLENNIUM MANAGEMENT LLC | 1273087 | 30.79K | 43.10K | Dec 31, 2025 |
| 18 | TWO SIGMA INVESTMENTS, LP | 1179392 | 30.41K | 57.79K | Jun 30, 2026 |
| 19 | STIFEL FINANCIAL CORP | 720672 | 27.90K | 53.01K | Jun 30, 2026 |
| 20 | JANE STREET GROUP, LLC | 1595888 | 27K | 51.30K | Jun 30, 2026 |
Data sourced from SEC Form 13F institutional holdings reports. Positions reflect the most recent filing per institution.