LYRA THERAPEUTICS, INC.

PublicCIK: 1327273
LYRAOTC
Location

WATERTOWN, MA

13F Filings

Institutional Holders

LYRA THERAPEUTICS, INC.LYRA— Latest position per institution from SEC 13F filings

15

Institutional holders

462.15K

Total shares held

2.19M

Estimated value

23.11K

Avg. position size

1

PERCEPTIVE ADVISORS LLC

CIK 1224962

Shares

229.38K

Value

1.50M

Filed

Sep 30, 2025

2

SABBY MANAGEMENT, LLC

CIK 1535610

Shares

104.06K

Value

51.10K

Filed

Mar 31, 2026

3

VANGUARD GROUP INC

CIK 102909

Shares

28.75K

Value

189.49K

Filed

Sep 30, 2025

4

IKARIAN CAPITAL, LLC

CIK 1778253

Shares

21.16K

Value

65.18K

Filed

Dec 31, 2025

5

CITADEL ADVISORS LLC

CIK 1423053

Shares

19.48K

Value

128.40K

Filed

Sep 30, 2025

6

DRW SECURITIES, LLC

CIK 1481986

Shares

16.81K

Value

51.78K

Filed

Dec 31, 2025

7

GEODE CAPITAL MANAGEMENT, LLC

CIK 1214717

Shares

12.25K

Value

37.73K

Filed

Dec 31, 2025

8

STATE OF WISCONSIN INVESTMENT BOARD

CIK 854157

Shares

10.50K

Value

94.08K

Filed

Jun 30, 2025

9

ARTIA GLOBAL PARTNERS LP

CIK 1937964

Shares

8.76K

Value

26.97K

Filed

Dec 31, 2025

10

BLACKROCK, INC.

CIK 2012383

Shares

2.39K

Value

7.37K

Filed

Dec 31, 2025

11

TOWER RESEARCH CAPITAL LLC (TRC)

CIK 1533421

Shares

2.19K

Value

6.75K

Filed

Dec 31, 2025

12

ROYAL BANK OF CANADA

CIK 1000275

Shares

1.95K

Value

6K

Filed

Dec 31, 2025

13

RUSSELL INVESTMENTS GROUP, LTD.

CIK 1692234

Shares

1.59K

Value

14.28K

Filed

Jun 30, 2025

14

UBS GROUP AG

CIK 1610520

Shares

675.00

Value

2.08K

Filed

Dec 31, 2025

15

VALLEY NATIONAL ADVISERS INC

CIK 773411

Shares

500.00

Value

4.00

Filed

Jun 30, 2025

16

FMR LLC

CIK 315066

Shares

406.00

Value

2.68K

Filed

Sep 30, 2025

17

SIGNATURE RESOURCES CAPITAL MANAGEMENT, LLC

CIK 1940917

Shares

400.00

Value

2.61K

Filed

Sep 30, 2025

18

EVERSOURCE WEALTH ADVISORS, LLC

CIK 1710537

Shares

338.00

Value

1.04K

Filed

Dec 31, 2025

19

MORGAN STANLEY

CIK 895421

Shares

334.00

Value

1.03K

Filed

Dec 31, 2025

20

JONES FINANCIAL COMPANIES LLLP

CIK 815917

Shares

210.00

Value

647.00

Filed

Dec 31, 2025

Data sourced from SEC Form 13F institutional holdings reports. Positions reflect the most recent filing per institution.