Filed: 5/15/2026ACC: 0001389933-26-000004
📋 What this filing means
DAFNA CAPITAL MANAGEMENT LLC filed this quarterly 13F‑HR report disclosing 83 equity positions with a total reported market value of $439.59M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
83
Positions
$439.59M
Total AUM (reported)
48.28M
Total Shares
Allocation by class
COM$276.30M62.9%
COM NEW$66.73M15.2%
ETF$51.17M11.6%
SPONSORED ADS$16.54M3.8%
SHS$7.42M1.7%
NOTE 2.250% 4/0$5.92M1.3%
SPONSORED ADR$5.30M1.2%
Portfolio Concentration
Top 3$122.33M27.8%
4–10$108.09M24.6%
11–25$108.01M24.6%
Rest$101.17M23.0%
Top 3 weight
27.8%
Top 10 weight
52.4%
Voting Authority Distribution
Total shares with voting rights: 48.28M
Sole
Full voting authority
48.28M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole83
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings83
Rows:
REVOLUTION MEDICINES INC
SOLEShares580.68K
TypeSH
Market value$56.47M
12.85%
Sole
580.68K
Shared
0.00
None
0.00
SPDR S&P BIOTECH ETF
SOLEShares318.50K
TypeSH
Market value$40.68M
9.25%
Sole
318.50K
Shared
0.00
None
0.00
STEREOTAXIS INC
SOLEShares13.68M
TypeSH
Market value$25.17M
5.73%
Sole
13.68M
Shared
0.00
None
0.00
DAY ONE BIOPHARMACEUTICALS I
SOLEShares978.46K
TypeSH
Market value$20.98M
4.77%
Sole
978.46K
Shared
0.00
None
0.00
ATRICURE INC
SOLEShares597.43K
TypeSH
Market value$17.04M
3.88%
Sole
597.43K
Shared
0.00
None
0.00
IDEAYA BIOSCIENCES INC
SOLEShares476.74K
TypeSH
Market value$15.88M
3.61%
Sole
476.74K
Shared
0.00
None
0.00
XENON PHARMACEUTICALS INC
SOLEShares250.77K
TypeSH
Market value$14.58M
3.32%
Sole
250.77K
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares217.50K
TypeSH
Market value$14.34M
3.26%
Sole
217.50K
Shared
0.00
None
0.00
COMPASS PATHWAYS PLC
SOLEShares2.42M
TypeSH
Market value$13.38M
3.04%
Sole
2.42M
Shared
0.00
None
0.00
NEKTAR THERAPEUTICS
SOLEShares165.18K
TypeSH
Market value$11.88M
2.70%
Sole
165.18K
Shared
0.00
None
0.00
ISHARES NASDAQ BIOTECH INDX
SOLEShares62.09K
TypeSH
Market value$10.48M
2.39%
Sole
62.09K
Shared
0.00
None
0.00
ARCUS BIOSCIENCES INC
SOLEShares443.83K
TypeSH
Market value$9.59M
2.18%
Sole
443.83K
Shared
0.00
None
0.00
NEUROCRINE BIOSCIENCES INC
SOLEShares70.61K
TypeSH
Market value$9.30M
2.12%
Sole
70.61K
Shared
0.00
None
0.00
LARIMAR THERAPEUTICS INC
SOLEShares2.03M
TypeSH
Market value$9.13M
2.08%
Sole
2.03M
Shared
0.00
None
0.00
BICARA THERAPEUTICS INC
SOLEShares421.73K
TypeSH
Market value$8.39M
1.91%
Sole
421.73K
Shared
0.00
None
0.00
AXOGEN INC
SOLEShares249.96K
TypeSH
Market value$8.28M
1.88%
Sole
249.96K
Shared
0.00
None
0.00
BIOHAVEN LTD
SOLEShares845.74K
TypeSH
Market value$7.15M
1.63%
Sole
845.74K
Shared
0.00
None
0.00
TANDEM DIABETES CARE INC
SOLEShares355.21K
TypeSH
Market value$6.81M
1.55%
Sole
355.21K
Shared
0.00
None
0.00
DENALI THERAPEUTICS INC
SOLEShares318.50K
TypeSH
Market value$6.12M
1.39%
Sole
318.50K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares4M
TypePRN
Market value$5.92M
1.35%
Sole
4M
Shared
0.00
None
0.00
CENTURY THERAPEUTICS INC
SOLEShares2.43M
TypeSH
Market value$5.50M
1.25%
Sole
2.43M
Shared
0.00
None
0.00
DEXCOM INC
SOLEShares86.28K
TypeSH
Market value$5.42M
1.23%
Sole
86.28K
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares267.40K
TypeSH
Market value$5.38M
1.22%
Sole
267.40K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares23.18K
TypeSH
Market value$5.30M
1.21%
Sole
23.18K
Shared
0.00
None
0.00
MBX BIOSCIENCES INC
SOLEShares175.47K
TypeSH
Market value$5.24M
1.19%
Sole
175.47K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
REVOLUTION MEDICINES INCSOLE | COM | 580.68K | SH | $56.47M 12.85% | 580.68K | 0.00 | 0.00 |
SPDR S&P BIOTECH ETFSOLE | ETF | 318.50K | SH | $40.68M 9.25% | 318.50K | 0.00 | 0.00 |
STEREOTAXIS INCSOLE | COM NEW | 13.68M | SH | $25.17M 5.73% | 13.68M | 0.00 | 0.00 |
DAY ONE BIOPHARMACEUTICALS ISOLE | COM | 978.46K | SH | $20.98M 4.77% | 978.46K | 0.00 | 0.00 |
ATRICURE INCSOLE | COM | 597.43K | SH | $17.04M 3.88% | 597.43K | 0.00 | 0.00 |
IDEAYA BIOSCIENCES INCSOLE | COM | 476.74K | SH | $15.88M 3.61% | 476.74K | 0.00 | 0.00 |
XENON PHARMACEUTICALS INCSOLE | COM | 250.77K | SH | $14.58M 3.32% | 250.77K | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 217.50K | SH | $14.34M 3.26% | 217.50K | 0.00 | 0.00 |
COMPASS PATHWAYS PLCSOLE | SPONSORED ADS | 2.42M | SH | $13.38M 3.04% | 2.42M | 0.00 | 0.00 |
NEKTAR THERAPEUTICSSOLE | COM NEW | 165.18K | SH | $11.88M 2.70% | 165.18K | 0.00 | 0.00 |
ISHARES NASDAQ BIOTECH INDXSOLE | ETF | 62.09K | SH | $10.48M 2.39% | 62.09K | 0.00 | 0.00 |
ARCUS BIOSCIENCES INCSOLE | COM | 443.83K | SH | $9.59M 2.18% | 443.83K | 0.00 | 0.00 |
NEUROCRINE BIOSCIENCES INCSOLE | COM | 70.61K | SH | $9.30M 2.12% | 70.61K | 0.00 | 0.00 |
LARIMAR THERAPEUTICS INCSOLE | COM | 2.03M | SH | $9.13M 2.08% | 2.03M | 0.00 | 0.00 |
BICARA THERAPEUTICS INCSOLE | COM | 421.73K | SH | $8.39M 1.91% | 421.73K | 0.00 | 0.00 |
AXOGEN INCSOLE | COM | 249.96K | SH | $8.28M 1.88% | 249.96K | 0.00 | 0.00 |
BIOHAVEN LTDSOLE | COM | 845.74K | SH | $7.15M 1.63% | 845.74K | 0.00 | 0.00 |
TANDEM DIABETES CARE INCSOLE | COM NEW | 355.21K | SH | $6.81M 1.55% | 355.21K | 0.00 | 0.00 |
DENALI THERAPEUTICS INCSOLE | COM | 318.50K | SH | $6.12M 1.39% | 318.50K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | NOTE 2.250% 4/0 | 4M | PRN | $5.92M 1.35% | 4M | 0.00 | 0.00 |
CENTURY THERAPEUTICS INCSOLE | COM | 2.43M | SH | $5.50M 1.25% | 2.43M | 0.00 | 0.00 |
DEXCOM INCSOLE | COM | 86.28K | SH | $5.42M 1.23% | 86.28K | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 267.40K | SH | $5.38M 1.22% | 267.40K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | SPONSORED ADR | 23.18K | SH | $5.30M 1.21% | 23.18K | 0.00 | 0.00 |
MBX BIOSCIENCES INCSOLE | COM | 175.47K | SH | $5.24M 1.19% | 175.47K | 0.00 | 0.00 |
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