Filed: 2/17/2026ACC: 0001389933-26-000002
📋 What this filing means
DAFNA CAPITAL MANAGEMENT LLC filed this quarterly 13F‑HR report disclosing 77 equity positions with a total reported market value of $430.52M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
77
Positions
$430.52M
Total AUM (reported)
44.48M
Total Shares
Allocation by class
COM$263.44M61.2%
COM NEW$75.15M17.5%
ETF$52.52M12.2%
SPONSORED ADS$9.54M2.2%
SHS$6.66M1.5%
SPONSORED ADR$6.01M1.4%
NOTE 2.250% 4/0$5.46M1.3%
Portfolio Concentration
Top 3$120.64M28.0%
4–10$115.51M26.8%
11–25$96.63M22.4%
Rest$97.73M22.7%
Top 3 weight
28.0%
Top 10 weight
54.9%
Voting Authority Distribution
Total shares with voting rights: 44.48M
Sole
Full voting authority
44.48M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole77
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings77
Rows:
REVOLUTION MEDICINES INC
SOLEShares604.51K
TypeSH
Market value$48.15M
11.18%
Sole
604.51K
Shared
0.00
None
0.00
SPDR S&P BIOTECH ETF
SOLEShares336.50K
TypeSH
Market value$41.03M
9.53%
Sole
336.50K
Shared
0.00
None
0.00
STEREOTAXIS INC
SOLEShares13.68M
TypeSH
Market value$31.47M
7.31%
Sole
13.68M
Shared
0.00
None
0.00
ATRICURE INC
SOLEShares597.43K
TypeSH
Market value$23.63M
5.49%
Sole
597.43K
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares371K
TypeSH
Market value$23.57M
5.48%
Sole
371K
Shared
0.00
None
0.00
IDEAYA BIOSCIENCES INC
SOLEShares506.74K
TypeSH
Market value$17.52M
4.07%
Sole
506.74K
Shared
0.00
None
0.00
AXOGEN INC
SOLEShares476.83K
TypeSH
Market value$15.61M
3.63%
Sole
476.83K
Shared
0.00
None
0.00
XENON PHARMACEUTICALS INC
SOLEShares287.94K
TypeSH
Market value$12.91M
3.00%
Sole
287.94K
Shared
0.00
None
0.00
ISHARES NASDAQ BIOTECH INDX
SOLEShares68.09K
TypeSH
Market value$11.49M
2.67%
Sole
68.09K
Shared
0.00
None
0.00
BIOHAVEN LTD
SOLEShares955.24K
TypeSH
Market value$10.78M
2.51%
Sole
955.24K
Shared
0.00
None
0.00
ARCUS BIOSCIENCES INC
SOLEShares431.33K
TypeSH
Market value$10.28M
2.39%
Sole
431.33K
Shared
0.00
None
0.00
NEUROCRINE BIOSCIENCES INC
SOLEShares70.61K
TypeSH
Market value$10.02M
2.33%
Sole
70.61K
Shared
0.00
None
0.00
DAY ONE BIOPHARMACEUTICALS I
SOLEShares999.16K
TypeSH
Market value$9.31M
2.16%
Sole
999.16K
Shared
0.00
None
0.00
TANDEM DIABETES CARE INC
SOLEShares355.21K
TypeSH
Market value$7.81M
1.81%
Sole
355.21K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares28.18K
TypeSH
Market value$6.01M
1.40%
Sole
28.18K
Shared
0.00
None
0.00
DEXCOM INC
SOLEShares88.28K
TypeSH
Market value$5.86M
1.36%
Sole
88.28K
Shared
0.00
None
0.00
SYNDAX PHARMACEUTICALS INC
SOLEShares277.86K
TypeSH
Market value$5.84M
1.36%
Sole
277.86K
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares356.80K
TypeSH
Market value$5.76M
1.34%
Sole
356.80K
Shared
0.00
None
0.00
COMPASS PATHWAYS PLC
SOLEShares811.05K
TypeSH
Market value$5.60M
1.30%
Sole
811.05K
Shared
0.00
None
0.00
INOGEN INC
SOLEShares827.07K
TypeSH
Market value$5.56M
1.29%
Sole
827.07K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares4M
TypePRN
Market value$5.46M
1.27%
Sole
4M
Shared
0.00
None
0.00
DENALI THERAPEUTICS INC
SOLEShares318.50K
TypeSH
Market value$5.26M
1.22%
Sole
318.50K
Shared
0.00
None
0.00
MBX BIOSCIENCES INC
SOLEShares165.26K
TypeSH
Market value$5.21M
1.21%
Sole
165.26K
Shared
0.00
None
0.00
BICARA THERAPEUTICS INC
SOLEShares261.58K
TypeSH
Market value$4.40M
1.02%
Sole
261.58K
Shared
0.00
None
0.00
GALAPAGOS NV
SOLEShares130.18K
TypeSH
Market value$4.26M
0.99%
Sole
130.18K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
REVOLUTION MEDICINES INCSOLE | COM | 604.51K | SH | $48.15M 11.18% | 604.51K | 0.00 | 0.00 |
SPDR S&P BIOTECH ETFSOLE | ETF | 336.50K | SH | $41.03M 9.53% | 336.50K | 0.00 | 0.00 |
STEREOTAXIS INCSOLE | COM NEW | 13.68M | SH | $31.47M 7.31% | 13.68M | 0.00 | 0.00 |
ATRICURE INCSOLE | COM | 597.43K | SH | $23.63M 5.49% | 597.43K | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 371K | SH | $23.57M 5.48% | 371K | 0.00 | 0.00 |
IDEAYA BIOSCIENCES INCSOLE | COM | 506.74K | SH | $17.52M 4.07% | 506.74K | 0.00 | 0.00 |
AXOGEN INCSOLE | COM | 476.83K | SH | $15.61M 3.63% | 476.83K | 0.00 | 0.00 |
XENON PHARMACEUTICALS INCSOLE | COM | 287.94K | SH | $12.91M 3.00% | 287.94K | 0.00 | 0.00 |
ISHARES NASDAQ BIOTECH INDXSOLE | ETF | 68.09K | SH | $11.49M 2.67% | 68.09K | 0.00 | 0.00 |
BIOHAVEN LTDSOLE | COM | 955.24K | SH | $10.78M 2.51% | 955.24K | 0.00 | 0.00 |
ARCUS BIOSCIENCES INCSOLE | COM | 431.33K | SH | $10.28M 2.39% | 431.33K | 0.00 | 0.00 |
NEUROCRINE BIOSCIENCES INCSOLE | COM | 70.61K | SH | $10.02M 2.33% | 70.61K | 0.00 | 0.00 |
DAY ONE BIOPHARMACEUTICALS ISOLE | COM | 999.16K | SH | $9.31M 2.16% | 999.16K | 0.00 | 0.00 |
TANDEM DIABETES CARE INCSOLE | COM NEW | 355.21K | SH | $7.81M 1.81% | 355.21K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | SPONSORED ADR | 28.18K | SH | $6.01M 1.40% | 28.18K | 0.00 | 0.00 |
DEXCOM INCSOLE | COM | 88.28K | SH | $5.86M 1.36% | 88.28K | 0.00 | 0.00 |
SYNDAX PHARMACEUTICALS INCSOLE | COM | 277.86K | SH | $5.84M 1.36% | 277.86K | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 356.80K | SH | $5.76M 1.34% | 356.80K | 0.00 | 0.00 |
COMPASS PATHWAYS PLCSOLE | SPONSORED ADS | 811.05K | SH | $5.60M 1.30% | 811.05K | 0.00 | 0.00 |
INOGEN INCSOLE | COM | 827.07K | SH | $5.56M 1.29% | 827.07K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | NOTE 2.250% 4/0 | 4M | PRN | $5.46M 1.27% | 4M | 0.00 | 0.00 |
DENALI THERAPEUTICS INCSOLE | COM | 318.50K | SH | $5.26M 1.22% | 318.50K | 0.00 | 0.00 |
MBX BIOSCIENCES INCSOLE | COM | 165.26K | SH | $5.21M 1.21% | 165.26K | 0.00 | 0.00 |
BICARA THERAPEUTICS INCSOLE | COM | 261.58K | SH | $4.40M 1.02% | 261.58K | 0.00 | 0.00 |
GALAPAGOS NVSOLE | SPON ADR | 130.18K | SH | $4.26M 0.99% | 130.18K | 0.00 | 0.00 |
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