Filed: 11/14/2025ACC: 0001389933-25-000008
📋 What this filing means
DAFNA CAPITAL MANAGEMENT LLC filed this quarterly 13F‑HR report disclosing 75 equity positions with a total reported market value of $404.79M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
75
Positions
$404.79M
Total AUM (reported)
43.99M
Total Shares
Allocation by class
COM$239.51M59.2%
COM NEW$72.74M18.0%
ETF$55.03M13.6%
SPONSORED ADS$8.35M2.1%
SPONSORED ADR$6.60M1.6%
SHS$6.53M1.6%
NOTE 2.250% 4/0$5.44M1.3%
Portfolio Concentration
Top 3$113.47M28.0%
4–10$117.63M29.1%
11–25$86.36M21.3%
Rest$87.33M21.6%
Top 3 weight
28.0%
Top 10 weight
57.1%
Voting Authority Distribution
Total shares with voting rights: 43.99M
Sole
Full voting authority
43.99M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole75
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings75
Rows:
STEREOTAXIS INC
SOLEShares13.68M
TypeSH
Market value$42.55M
10.51%
Sole
13.68M
Shared
0.00
None
0.00
SPDR S&P BIOTECH ETF
SOLEShares401.50K
TypeSH
Market value$40.23M
9.94%
Sole
401.50K
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares657.18K
TypeSH
Market value$30.69M
7.58%
Sole
657.18K
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares394.94K
TypeSH
Market value$21.71M
5.36%
Sole
394.94K
Shared
0.00
None
0.00
ATRICURE INC
SOLEShares592.27K
TypeSH
Market value$20.88M
5.16%
Sole
592.27K
Shared
0.00
None
0.00
MERUS BV
SOLEShares220.45K
TypeSH
Market value$20.76M
5.13%
Sole
220.45K
Shared
0.00
None
0.00
ISHARES NASDAQ BIOTECH INDX
SOLEShares102.50K
TypeSH
Market value$14.80M
3.66%
Sole
102.50K
Shared
0.00
None
0.00
IDEAYA BIOSCIENCES INC
SOLEShares539.92K
TypeSH
Market value$14.69M
3.63%
Sole
539.92K
Shared
0.00
None
0.00
AXOGEN INC
SOLEShares742.28K
TypeSH
Market value$13.24M
3.27%
Sole
742.28K
Shared
0.00
None
0.00
XENON PHARMACEUTICALS INC
SOLEShares287.94K
TypeSH
Market value$11.56M
2.86%
Sole
287.94K
Shared
0.00
None
0.00
NEUROCRINE BIOSCIENCES INC
SOLEShares70.61K
TypeSH
Market value$9.91M
2.45%
Sole
70.61K
Shared
0.00
None
0.00
ARCUS BIOSCIENCES INC
SOLEShares627.63K
TypeSH
Market value$8.54M
2.11%
Sole
627.63K
Shared
0.00
None
0.00
SYNDAX PHARMACEUTICALS INC
SOLEShares500.70K
TypeSH
Market value$7.70M
1.90%
Sole
500.70K
Shared
0.00
None
0.00
DAY ONE BIOPHARMACEUTICALS I
SOLEShares999.16K
TypeSH
Market value$7.04M
1.74%
Sole
999.16K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares33.18K
TypeSH
Market value$6.60M
1.63%
Sole
33.18K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares4M
TypePRN
Market value$5.44M
1.34%
Sole
4M
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares422.73K
TypeSH
Market value$5.15M
1.27%
Sole
422.73K
Shared
0.00
None
0.00
BICARA THERAPEUTICS INC
SOLEShares317K
TypeSH
Market value$5.01M
1.24%
Sole
317K
Shared
0.00
None
0.00
INOGEN INC
SOLEShares605.63K
TypeSH
Market value$4.95M
1.22%
Sole
605.63K
Shared
0.00
None
0.00
COMPASS PATHWAYS PLC
SOLEShares811.05K
TypeSH
Market value$4.65M
1.15%
Sole
811.05K
Shared
0.00
None
0.00
GALAPAGOS NV
SOLEShares130.18K
TypeSH
Market value$4.51M
1.11%
Sole
130.18K
Shared
0.00
None
0.00
DEXCOM INC
SOLEShares65.55K
TypeSH
Market value$4.41M
1.09%
Sole
65.55K
Shared
0.00
None
0.00
TANDEM DIABETES CARE INC
SOLEShares355.21K
TypeSH
Market value$4.31M
1.07%
Sole
355.21K
Shared
0.00
None
0.00
KURA ONCOLOGY INC
SOLEShares463.37K
TypeSH
Market value$4.10M
1.01%
Sole
463.37K
Shared
0.00
None
0.00
ALKERMES PLC
SOLEShares134.75K
TypeSH
Market value$4.04M
1.00%
Sole
134.75K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
STEREOTAXIS INCSOLE | COM NEW | 13.68M | SH | $42.55M 10.51% | 13.68M | 0.00 | 0.00 |
SPDR S&P BIOTECH ETFSOLE | ETF | 401.50K | SH | $40.23M 9.94% | 401.50K | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 657.18K | SH | $30.69M 7.58% | 657.18K | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 394.94K | SH | $21.71M 5.36% | 394.94K | 0.00 | 0.00 |
ATRICURE INCSOLE | COM | 592.27K | SH | $20.88M 5.16% | 592.27K | 0.00 | 0.00 |
MERUS BVSOLE | COM | 220.45K | SH | $20.76M 5.13% | 220.45K | 0.00 | 0.00 |
ISHARES NASDAQ BIOTECH INDXSOLE | ETF | 102.50K | SH | $14.80M 3.66% | 102.50K | 0.00 | 0.00 |
IDEAYA BIOSCIENCES INCSOLE | COM | 539.92K | SH | $14.69M 3.63% | 539.92K | 0.00 | 0.00 |
AXOGEN INCSOLE | COM | 742.28K | SH | $13.24M 3.27% | 742.28K | 0.00 | 0.00 |
XENON PHARMACEUTICALS INCSOLE | COM | 287.94K | SH | $11.56M 2.86% | 287.94K | 0.00 | 0.00 |
NEUROCRINE BIOSCIENCES INCSOLE | COM | 70.61K | SH | $9.91M 2.45% | 70.61K | 0.00 | 0.00 |
ARCUS BIOSCIENCES INCSOLE | COM | 627.63K | SH | $8.54M 2.11% | 627.63K | 0.00 | 0.00 |
SYNDAX PHARMACEUTICALS INCSOLE | COM | 500.70K | SH | $7.70M 1.90% | 500.70K | 0.00 | 0.00 |
DAY ONE BIOPHARMACEUTICALS ISOLE | COM | 999.16K | SH | $7.04M 1.74% | 999.16K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | SPONSORED ADR | 33.18K | SH | $6.60M 1.63% | 33.18K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | NOTE 2.250% 4/0 | 4M | PRN | $5.44M 1.34% | 4M | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 422.73K | SH | $5.15M 1.27% | 422.73K | 0.00 | 0.00 |
BICARA THERAPEUTICS INCSOLE | COM | 317K | SH | $5.01M 1.24% | 317K | 0.00 | 0.00 |
INOGEN INCSOLE | COM | 605.63K | SH | $4.95M 1.22% | 605.63K | 0.00 | 0.00 |
COMPASS PATHWAYS PLCSOLE | SPONSORED ADS | 811.05K | SH | $4.65M 1.15% | 811.05K | 0.00 | 0.00 |
GALAPAGOS NVSOLE | SPON ADR | 130.18K | SH | $4.51M 1.11% | 130.18K | 0.00 | 0.00 |
DEXCOM INCSOLE | COM | 65.55K | SH | $4.41M 1.09% | 65.55K | 0.00 | 0.00 |
TANDEM DIABETES CARE INCSOLE | COM NEW | 355.21K | SH | $4.31M 1.07% | 355.21K | 0.00 | 0.00 |
KURA ONCOLOGY INCSOLE | COM | 463.37K | SH | $4.10M 1.01% | 463.37K | 0.00 | 0.00 |
ALKERMES PLCSOLE | SHS | 134.75K | SH | $4.04M 1.00% | 134.75K | 0.00 | 0.00 |
Page 1 of 3