Filed: 5/15/2025ACC: 0001389933-25-000002
📋 What this filing means
DAFNA CAPITAL MANAGEMENT LLC filed this quarterly 13F‑HR report disclosing 83 equity positions with a total reported market value of $352.66M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
83
Positions
$352.66M
Total AUM (reported)
51.20M
Total Shares
Allocation by class
COM$222.07M63.0%
COM NEW$46.22M13.1%
ETF$45.92M13.0%
SPONSORED ADR$12.53M3.6%
SPONSORED ADS$6.18M1.8%
NOTE 2.250% 4/0$4.71M1.3%
SHS$4.53M1.3%
Portfolio Concentration
Top 3$80.09M22.7%
4–10$106.26M30.1%
11–25$91.53M26.0%
Rest$74.79M21.2%
Top 3 weight
22.7%
Top 10 weight
52.8%
Voting Authority Distribution
Total shares with voting rights: 51.20M
Sole
Full voting authority
51.20M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole83
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings83
Rows:
SPDR S&P BIOTECH ETF
SOLEShares404.50K
TypeSH
Market value$32.81M
9.30%
Sole
404.50K
Shared
0.00
None
0.00
STEREOTAXIS INC
SOLEShares13.68M
TypeSH
Market value$24.08M
6.83%
Sole
13.68M
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares656.18K
TypeSH
Market value$23.20M
6.58%
Sole
656.18K
Shared
0.00
None
0.00
MERUS N V
SOLEShares461.80K
TypeSH
Market value$19.44M
5.51%
Sole
461.80K
Shared
0.00
None
0.00
ATRICURE INC
SOLEShares592.27K
TypeSH
Market value$19.11M
5.42%
Sole
592.27K
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares398.10K
TypeSH
Market value$16.00M
4.54%
Sole
398.10K
Shared
0.00
None
0.00
BLUEPRINT MEDICINES CORP
SOLEShares152.26K
TypeSH
Market value$13.48M
3.82%
Sole
152.26K
Shared
0.00
None
0.00
ISHARES NASDAQ BIOTECH INDX
SOLEShares102.50K
TypeSH
Market value$13.11M
3.72%
Sole
102.50K
Shared
0.00
None
0.00
AXOGEN INC
SOLEShares680.78K
TypeSH
Market value$12.59M
3.57%
Sole
680.78K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares80.40K
TypeSH
Market value$12.53M
3.55%
Sole
80.40K
Shared
0.00
None
0.00
IDEAYA BIOSCIENCES INC
SOLEShares589.33K
TypeSH
Market value$9.65M
2.74%
Sole
589.33K
Shared
0.00
None
0.00
XENON PHARMACEUTICALS INC
SOLEShares273.74K
TypeSH
Market value$9.18M
2.60%
Sole
273.74K
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares752.36K
TypeSH
Market value$8.68M
2.46%
Sole
752.36K
Shared
0.00
None
0.00
NEUROCRINE BIOSCIENCES INC
SOLEShares71.61K
TypeSH
Market value$7.92M
2.25%
Sole
71.61K
Shared
0.00
None
0.00
SYNDAX PHARMACEUTICALS INC
SOLEShares544.50K
TypeSH
Market value$6.69M
1.90%
Sole
544.50K
Shared
0.00
None
0.00
DAY ONE BIOPHARMACEUTICALS I
SOLEShares731.36K
TypeSH
Market value$5.80M
1.64%
Sole
731.36K
Shared
0.00
None
0.00
TANDEM DIABETES CARE INC
SOLEShares294.21K
TypeSH
Market value$5.64M
1.60%
Sole
294.21K
Shared
0.00
None
0.00
UROGEN PHARMA LTD
SOLEShares492.51K
TypeSH
Market value$5.45M
1.54%
Sole
492.51K
Shared
0.00
None
0.00
BIOHAVEN LTD
SOLEShares220.24K
TypeSH
Market value$5.29M
1.50%
Sole
220.24K
Shared
0.00
None
0.00
MINERALYS THERAPEUTICS INC
SOLEShares309.20K
TypeSH
Market value$4.91M
1.39%
Sole
309.20K
Shared
0.00
None
0.00
ARCUS BIOSCIENCES INC
SOLEShares625.13K
TypeSH
Market value$4.91M
1.39%
Sole
625.13K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares4M
TypePRN
Market value$4.71M
1.34%
Sole
4M
Shared
0.00
None
0.00
DEXCOM INC
SOLEShares65.55K
TypeSH
Market value$4.48M
1.27%
Sole
65.55K
Shared
0.00
None
0.00
BIOCRYST PHARMACEUTICALS INC
SOLEShares558.25K
TypeSH
Market value$4.19M
1.19%
Sole
558.25K
Shared
0.00
None
0.00
EDGEWISE THERAPEUTICS INC
SOLEShares183.14K
TypeSH
Market value$4.03M
1.14%
Sole
183.14K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
SPDR S&P BIOTECH ETFSOLE | ETF | 404.50K | SH | $32.81M 9.30% | 404.50K | 0.00 | 0.00 |
STEREOTAXIS INCSOLE | COM NEW | 13.68M | SH | $24.08M 6.83% | 13.68M | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 656.18K | SH | $23.20M 6.58% | 656.18K | 0.00 | 0.00 |
MERUS N VSOLE | COM | 461.80K | SH | $19.44M 5.51% | 461.80K | 0.00 | 0.00 |
ATRICURE INCSOLE | COM | 592.27K | SH | $19.11M 5.42% | 592.27K | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 398.10K | SH | $16.00M 4.54% | 398.10K | 0.00 | 0.00 |
BLUEPRINT MEDICINES CORPSOLE | COM | 152.26K | SH | $13.48M 3.82% | 152.26K | 0.00 | 0.00 |
ISHARES NASDAQ BIOTECH INDXSOLE | ETF | 102.50K | SH | $13.11M 3.72% | 102.50K | 0.00 | 0.00 |
AXOGEN INCSOLE | COM | 680.78K | SH | $12.59M 3.57% | 680.78K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | SPONSORED ADR | 80.40K | SH | $12.53M 3.55% | 80.40K | 0.00 | 0.00 |
IDEAYA BIOSCIENCES INCSOLE | COM | 589.33K | SH | $9.65M 2.74% | 589.33K | 0.00 | 0.00 |
XENON PHARMACEUTICALS INCSOLE | COM | 273.74K | SH | $9.18M 2.60% | 273.74K | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 752.36K | SH | $8.68M 2.46% | 752.36K | 0.00 | 0.00 |
NEUROCRINE BIOSCIENCES INCSOLE | COM | 71.61K | SH | $7.92M 2.25% | 71.61K | 0.00 | 0.00 |
SYNDAX PHARMACEUTICALS INCSOLE | COM | 544.50K | SH | $6.69M 1.90% | 544.50K | 0.00 | 0.00 |
DAY ONE BIOPHARMACEUTICALS ISOLE | COM | 731.36K | SH | $5.80M 1.64% | 731.36K | 0.00 | 0.00 |
TANDEM DIABETES CARE INCSOLE | COM NEW | 294.21K | SH | $5.64M 1.60% | 294.21K | 0.00 | 0.00 |
UROGEN PHARMA LTDSOLE | COM | 492.51K | SH | $5.45M 1.54% | 492.51K | 0.00 | 0.00 |
BIOHAVEN LTDSOLE | COM | 220.24K | SH | $5.29M 1.50% | 220.24K | 0.00 | 0.00 |
MINERALYS THERAPEUTICS INCSOLE | COM | 309.20K | SH | $4.91M 1.39% | 309.20K | 0.00 | 0.00 |
ARCUS BIOSCIENCES INCSOLE | COM | 625.13K | SH | $4.91M 1.39% | 625.13K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | NOTE 2.250% 4/0 | 4M | PRN | $4.71M 1.34% | 4M | 0.00 | 0.00 |
DEXCOM INCSOLE | COM | 65.55K | SH | $4.48M 1.27% | 65.55K | 0.00 | 0.00 |
BIOCRYST PHARMACEUTICALS INCSOLE | COM | 558.25K | SH | $4.19M 1.19% | 558.25K | 0.00 | 0.00 |
EDGEWISE THERAPEUTICS INCSOLE | COM | 183.14K | SH | $4.03M 1.14% | 183.14K | 0.00 | 0.00 |
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