Filed: 8/14/2025ACC: 0001389932-25-000011
📋 What this filing means
DAFNA CAPITAL MANAGEMENT LLC filed this quarterly 13F‑HR report disclosing 76 equity positions with a total reported market value of $362.25M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
76
Positions
$362.25M
Total AUM (reported)
46.47M
Total Shares
Allocation by class
COM$228.44M63.1%
COM NEW$48.31M13.3%
ETF$47.43M13.1%
SPONSORED ADR$12.54M3.5%
SPONSORED ADS$6.36M1.8%
NOTE 2.250% 4/0$5.01M1.4%
SHS$4.61M1.3%
Portfolio Concentration
Top 3$88.37M24.4%
4–10$113.70M31.4%
11–25$88.06M24.3%
Rest$72.12M19.9%
Top 3 weight
24.4%
Top 10 weight
55.8%
Voting Authority Distribution
Total shares with voting rights: 46.47M
Sole
Full voting authority
46.47M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole76
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings76
Rows:
SPDR S&P BIOTECH ETF
SOLEShares415.50K
TypeSH
Market value$34.46M
9.51%
Sole
415.50K
Shared
0.00
None
0.00
STEREOTAXIS INC
SOLEShares13.68M
TypeSH
Market value$29.00M
8.01%
Sole
13.68M
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares677.18K
TypeSH
Market value$24.91M
6.88%
Sole
677.18K
Shared
0.00
None
0.00
BLUEPRINT MEDICINES CORP
SOLEShares168.76K
TypeSH
Market value$21.63M
5.97%
Sole
168.76K
Shared
0.00
None
0.00
MERUS BV
SOLEShares398.80K
TypeSH
Market value$20.98M
5.79%
Sole
398.80K
Shared
0.00
None
0.00
ATRICURE INC
SOLEShares592.27K
TypeSH
Market value$19.41M
5.36%
Sole
592.27K
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares398.10K
TypeSH
Market value$13.15M
3.63%
Sole
398.10K
Shared
0.00
None
0.00
IDEAYA BIOSCIENCES INC
SOLEShares619.09K
TypeSH
Market value$13.01M
3.59%
Sole
619.09K
Shared
0.00
None
0.00
ISHARES NASDAQ BIOTECH INDX
SOLEShares102.50K
TypeSH
Market value$12.97M
3.58%
Sole
102.50K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares72.68K
TypeSH
Market value$12.54M
3.46%
Sole
72.68K
Shared
0.00
None
0.00
XENON PHARMACEUTICALS INC
SOLEShares287.94K
TypeSH
Market value$9.01M
2.49%
Sole
287.94K
Shared
0.00
None
0.00
NEUROCRINE BIOSCIENCES INC
SOLEShares70.61K
TypeSH
Market value$8.88M
2.45%
Sole
70.61K
Shared
0.00
None
0.00
AXOGEN INC
SOLEShares741.78K
TypeSH
Market value$8.05M
2.22%
Sole
741.78K
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares581.76K
TypeSH
Market value$6.58M
1.82%
Sole
581.76K
Shared
0.00
None
0.00
DEXCOM INC
SOLEShares65.55K
TypeSH
Market value$5.72M
1.58%
Sole
65.55K
Shared
0.00
None
0.00
DAY ONE BIOPHARMACEUTICALS I
SOLEShares879.16K
TypeSH
Market value$5.71M
1.58%
Sole
879.16K
Shared
0.00
None
0.00
STOKE THERAPEUTICS INC
SOLEShares501.97K
TypeSH
Market value$5.70M
1.57%
Sole
501.97K
Shared
0.00
None
0.00
TANDEM DIABETES CARE INC
SOLEShares294.21K
TypeSH
Market value$5.48M
1.51%
Sole
294.21K
Shared
0.00
None
0.00
ARCUS BIOSCIENCES INC
SOLEShares627.63K
TypeSH
Market value$5.11M
1.41%
Sole
627.63K
Shared
0.00
None
0.00
SYNDAX PHARMACEUTICALS INC
SOLEShares543.60K
TypeSH
Market value$5.09M
1.41%
Sole
543.60K
Shared
0.00
None
0.00
MINERALYS THERAPEUTICS INC
SOLEShares371.52K
TypeSH
Market value$5.03M
1.39%
Sole
371.52K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares4M
TypePRN
Market value$5.01M
1.38%
Sole
4M
Shared
0.00
None
0.00
UROGEN PHARMA LTD
SOLEShares349.51K
TypeSH
Market value$4.79M
1.32%
Sole
349.51K
Shared
0.00
None
0.00
INOGEN INC
SOLEShares605.63K
TypeSH
Market value$4.26M
1.18%
Sole
605.63K
Shared
0.00
None
0.00
GALAPAGOS NV
SOLEShares130.18K
TypeSH
Market value$3.64M
1.01%
Sole
130.18K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
SPDR S&P BIOTECH ETFSOLE | ETF | 415.50K | SH | $34.46M 9.51% | 415.50K | 0.00 | 0.00 |
STEREOTAXIS INCSOLE | COM NEW | 13.68M | SH | $29.00M 8.01% | 13.68M | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 677.18K | SH | $24.91M 6.88% | 677.18K | 0.00 | 0.00 |
BLUEPRINT MEDICINES CORPSOLE | COM | 168.76K | SH | $21.63M 5.97% | 168.76K | 0.00 | 0.00 |
MERUS BVSOLE | COM | 398.80K | SH | $20.98M 5.79% | 398.80K | 0.00 | 0.00 |
ATRICURE INCSOLE | COM | 592.27K | SH | $19.41M 5.36% | 592.27K | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 398.10K | SH | $13.15M 3.63% | 398.10K | 0.00 | 0.00 |
IDEAYA BIOSCIENCES INCSOLE | COM | 619.09K | SH | $13.01M 3.59% | 619.09K | 0.00 | 0.00 |
ISHARES NASDAQ BIOTECH INDXSOLE | ETF | 102.50K | SH | $12.97M 3.58% | 102.50K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | SPONSORED ADR | 72.68K | SH | $12.54M 3.46% | 72.68K | 0.00 | 0.00 |
XENON PHARMACEUTICALS INCSOLE | COM | 287.94K | SH | $9.01M 2.49% | 287.94K | 0.00 | 0.00 |
NEUROCRINE BIOSCIENCES INCSOLE | COM | 70.61K | SH | $8.88M 2.45% | 70.61K | 0.00 | 0.00 |
AXOGEN INCSOLE | COM | 741.78K | SH | $8.05M 2.22% | 741.78K | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 581.76K | SH | $6.58M 1.82% | 581.76K | 0.00 | 0.00 |
DEXCOM INCSOLE | COM | 65.55K | SH | $5.72M 1.58% | 65.55K | 0.00 | 0.00 |
DAY ONE BIOPHARMACEUTICALS ISOLE | COM | 879.16K | SH | $5.71M 1.58% | 879.16K | 0.00 | 0.00 |
STOKE THERAPEUTICS INCSOLE | COM | 501.97K | SH | $5.70M 1.57% | 501.97K | 0.00 | 0.00 |
TANDEM DIABETES CARE INCSOLE | COM NEW | 294.21K | SH | $5.48M 1.51% | 294.21K | 0.00 | 0.00 |
ARCUS BIOSCIENCES INCSOLE | COM | 627.63K | SH | $5.11M 1.41% | 627.63K | 0.00 | 0.00 |
SYNDAX PHARMACEUTICALS INCSOLE | COM | 543.60K | SH | $5.09M 1.41% | 543.60K | 0.00 | 0.00 |
MINERALYS THERAPEUTICS INCSOLE | COM | 371.52K | SH | $5.03M 1.39% | 371.52K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | NOTE 2.250% 4/0 | 4M | PRN | $5.01M 1.38% | 4M | 0.00 | 0.00 |
UROGEN PHARMA LTDSOLE | COM | 349.51K | SH | $4.79M 1.32% | 349.51K | 0.00 | 0.00 |
INOGEN INCSOLE | COM | 605.63K | SH | $4.26M 1.18% | 605.63K | 0.00 | 0.00 |
GALAPAGOS NVSOLE | SPON ADR | 130.18K | SH | $3.64M 1.01% | 130.18K | 0.00 | 0.00 |
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