Filed: 2/14/2025ACC: 0001389932-25-000004
📋 What this filing means
DAFNA CAPITAL MANAGEMENT LLC filed this quarterly 13F‑HR report disclosing 82 equity positions with a total reported market value of $393.41M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
82
Positions
$393.41M
Total AUM (reported)
48.79M
Total Shares
Allocation by class
COM$239.70M60.9%
COM NEW$59.12M15.0%
ETF$49.35M12.5%
SPONSORED ADR$14.23M3.6%
SPONSORED ADS$7.16M1.8%
SHS$5.66M1.4%
NOTE 2.250% 4/0$4.41M1.1%
Portfolio Concentration
Top 3$94.60M24.0%
4–10$112.13M28.5%
11–25$106.17M27.0%
Rest$80.51M20.5%
Top 3 weight
24.0%
Top 10 weight
52.5%
Voting Authority Distribution
Total shares with voting rights: 48.79M
Sole
Full voting authority
48.79M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole82
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings82
Rows:
SPDR S&P BIOTECH ETF
SOLEShares397.50K
TypeSH
Market value$35.80M
9.10%
Sole
397.50K
Shared
0.00
None
0.00
STEREOTAXIS INC
SOLEShares13.68M
TypeSH
Market value$31.19M
7.93%
Sole
13.68M
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares631.18K
TypeSH
Market value$27.61M
7.02%
Sole
631.18K
Shared
0.00
None
0.00
ATRICURE INC
SOLEShares641.67K
TypeSH
Market value$19.61M
4.98%
Sole
641.67K
Shared
0.00
None
0.00
MERUS N V
SOLEShares451.80K
TypeSH
Market value$19.00M
4.83%
Sole
451.80K
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares398.10K
TypeSH
Market value$18.73M
4.76%
Sole
398.10K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares103.36K
TypeSH
Market value$14.23M
3.62%
Sole
103.36K
Shared
0.00
None
0.00
AXOGEN INC
SOLEShares846.88K
TypeSH
Market value$13.96M
3.55%
Sole
846.88K
Shared
0.00
None
0.00
ISHARES NASDAQ BIOTECH INDX
SOLEShares102.50K
TypeSH
Market value$13.55M
3.44%
Sole
102.50K
Shared
0.00
None
0.00
BLUEPRINT MEDICINES CORP
SOLEShares149.76K
TypeSH
Market value$13.06M
3.32%
Sole
149.76K
Shared
0.00
None
0.00
IDEAYA BIOSCIENCES INC
SOLEShares498.83K
TypeSH
Market value$12.82M
3.26%
Sole
498.83K
Shared
0.00
None
0.00
XENON PHARMACEUTICALS INC
SOLEShares273.74K
TypeSH
Market value$10.73M
2.73%
Sole
273.74K
Shared
0.00
None
0.00
NEUROCRINE BIOSCIENCES INC
SOLEShares71.61K
TypeSH
Market value$9.78M
2.48%
Sole
71.61K
Shared
0.00
None
0.00
DAY ONE BIOPHARMACEUTICALS I
SOLEShares731.36K
TypeSH
Market value$9.27M
2.36%
Sole
731.36K
Shared
0.00
None
0.00
BIOHAVEN LTD
SOLEShares220.24K
TypeSH
Market value$8.23M
2.09%
Sole
220.24K
Shared
0.00
None
0.00
TANDEM DIABETES CARE INC
SOLEShares223.21K
TypeSH
Market value$8.04M
2.04%
Sole
223.21K
Shared
0.00
None
0.00
SYNDAX PHARMACEUTICALS INC
SOLEShares542K
TypeSH
Market value$7.17M
1.82%
Sole
542K
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares811.68K
TypeSH
Market value$6.87M
1.75%
Sole
811.68K
Shared
0.00
None
0.00
UROGEN PHARMA LTD
SOLEShares492.51K
TypeSH
Market value$5.25M
1.33%
Sole
492.51K
Shared
0.00
None
0.00
DEXCOM INC
SOLEShares65.55K
TypeSH
Market value$5.10M
1.30%
Sole
65.55K
Shared
0.00
None
0.00
BIOCRYST PHARMACEUTICALS INC
SOLEShares667K
TypeSH
Market value$5.02M
1.27%
Sole
667K
Shared
0.00
None
0.00
EDGEWISE THERAPEUTICS INC
SOLEShares187.14K
TypeSH
Market value$5.00M
1.27%
Sole
187.14K
Shared
0.00
None
0.00
ASCENDIS PHARMA A/S
SOLEShares4M
TypePRN
Market value$4.41M
1.12%
Sole
4M
Shared
0.00
None
0.00
TELA BIO INC
SOLEShares1.44M
TypeSH
Market value$4.35M
1.11%
Sole
1.44M
Shared
0.00
None
0.00
PROQR THERAPEUTICS N V
SOLEShares1.57M
TypeSH
Market value$4.15M
1.06%
Sole
1.57M
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
SPDR S&P BIOTECH ETFSOLE | ETF | 397.50K | SH | $35.80M 9.10% | 397.50K | 0.00 | 0.00 |
STEREOTAXIS INCSOLE | COM NEW | 13.68M | SH | $31.19M 7.93% | 13.68M | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 631.18K | SH | $27.61M 7.02% | 631.18K | 0.00 | 0.00 |
ATRICURE INCSOLE | COM | 641.67K | SH | $19.61M 4.98% | 641.67K | 0.00 | 0.00 |
MERUS N VSOLE | COM | 451.80K | SH | $19.00M 4.83% | 451.80K | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 398.10K | SH | $18.73M 4.76% | 398.10K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | SPONSORED ADR | 103.36K | SH | $14.23M 3.62% | 103.36K | 0.00 | 0.00 |
AXOGEN INCSOLE | COM | 846.88K | SH | $13.96M 3.55% | 846.88K | 0.00 | 0.00 |
ISHARES NASDAQ BIOTECH INDXSOLE | ETF | 102.50K | SH | $13.55M 3.44% | 102.50K | 0.00 | 0.00 |
BLUEPRINT MEDICINES CORPSOLE | COM | 149.76K | SH | $13.06M 3.32% | 149.76K | 0.00 | 0.00 |
IDEAYA BIOSCIENCES INCSOLE | COM | 498.83K | SH | $12.82M 3.26% | 498.83K | 0.00 | 0.00 |
XENON PHARMACEUTICALS INCSOLE | COM | 273.74K | SH | $10.73M 2.73% | 273.74K | 0.00 | 0.00 |
NEUROCRINE BIOSCIENCES INCSOLE | COM | 71.61K | SH | $9.78M 2.48% | 71.61K | 0.00 | 0.00 |
DAY ONE BIOPHARMACEUTICALS ISOLE | COM | 731.36K | SH | $9.27M 2.36% | 731.36K | 0.00 | 0.00 |
BIOHAVEN LTDSOLE | COM | 220.24K | SH | $8.23M 2.09% | 220.24K | 0.00 | 0.00 |
TANDEM DIABETES CARE INCSOLE | COM NEW | 223.21K | SH | $8.04M 2.04% | 223.21K | 0.00 | 0.00 |
SYNDAX PHARMACEUTICALS INCSOLE | COM | 542K | SH | $7.17M 1.82% | 542K | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 811.68K | SH | $6.87M 1.75% | 811.68K | 0.00 | 0.00 |
UROGEN PHARMA LTDSOLE | COM | 492.51K | SH | $5.25M 1.33% | 492.51K | 0.00 | 0.00 |
DEXCOM INCSOLE | COM | 65.55K | SH | $5.10M 1.30% | 65.55K | 0.00 | 0.00 |
BIOCRYST PHARMACEUTICALS INCSOLE | COM | 667K | SH | $5.02M 1.27% | 667K | 0.00 | 0.00 |
EDGEWISE THERAPEUTICS INCSOLE | COM | 187.14K | SH | $5.00M 1.27% | 187.14K | 0.00 | 0.00 |
ASCENDIS PHARMA A/SSOLE | NOTE 2.250% 4/0 | 4M | PRN | $4.41M 1.12% | 4M | 0.00 | 0.00 |
TELA BIO INCSOLE | COM | 1.44M | SH | $4.35M 1.11% | 1.44M | 0.00 | 0.00 |
PROQR THERAPEUTICS N VSOLE | SHS EURO | 1.57M | SH | $4.15M 1.06% | 1.57M | 0.00 | 0.00 |
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