CAMBRIDGE, X0
BICYCLE THERAPEUTICS PLCBCYC— Latest position per institution from SEC 13F filings
15
Institutional holders
44.66M
Total shares held
343.47M
Estimated value
2.23M
Avg. position size
BAKER BROS. ADVISORS LP
CIK 1263508
Shares
10.89M
Value
46.15M
Filed
Jun 30, 2026
FCPM III SERVICES B.V.
CIK 2013410
Shares
3.47M
Value
14.71M
Filed
Jun 30, 2026
ARMISTICE CAPITAL, LLC
CIK 1601086
Shares
3.40M
Value
14.41M
Filed
Jun 30, 2026
LONG FOCUS CAPITAL MANAGEMENT, LLC
CIK 1602716
Shares
3.31M
Value
14.04M
Filed
Jun 30, 2026
PARADIGM BIOCAPITAL ADVISORS LP
CIK 1855655
Shares
3.25M
Value
80.84M
Filed
Mar 31, 2024
WESTFIELD CAPITAL MANAGEMENT CO LP
CIK 1177719
Shares
3.02M
Value
21.35M
Filed
Dec 31, 2025
ACADIAN ASSET MANAGEMENT LLC
CIK 916542
Shares
1.97M
Value
8.32K
Filed
Jun 30, 2026
SIREN, L.L.C.
CIK 2005245
Shares
1.56M
Value
7.24M
Filed
Mar 31, 2026
RENAISSANCE TECHNOLOGIES LLC
CIK 1037389
Shares
1.53M
Value
6.50M
Filed
Jun 30, 2026
GSK PLC
CIK 1131399
Shares
1.53M
Value
6.49M
Filed
Jun 30, 2026
BRAIDWELL LP
CIK 1920938
Shares
1.29M
Value
25.91M
Filed
Sep 30, 2023
DEEP TRACK CAPITAL, LP
CIK 1856083
Shares
1.20M
Value
8.36M
Filed
Jun 30, 2025
CANDRIAM S.C.A.
CIK 1537014
Shares
1.19M
Value
8.44M
Filed
Dec 31, 2025
PRINCIPAL FINANCIAL GROUP INC
CIK 1126328
Shares
1.17M
Value
5.45M
Filed
Mar 31, 2026
RA CAPITAL MANAGEMENT, L.P.
CIK 1346824
Shares
1.09M
Value
9.28M
Filed
Mar 31, 2025
POLAR CAPITAL HOLDINGS PLC
CIK 1837309
Shares
1M
Value
22.69M
Filed
Sep 30, 2024
TYBOURNE CAPITAL MANAGEMENT (HK) LTD
CIK 1553936
Shares
993.74K
Value
6.91M
Filed
Jun 30, 2025
FIRST LIGHT ASSET MANAGEMENT, LLC
CIK 1600004
Shares
967.01K
Value
21.88M
Filed
Sep 30, 2024
CAMBER CAPITAL MANAGEMENT LP
CIK 1444043
Shares
915K
Value
20.71K
Filed
Sep 30, 2024
MONTANOVA CAPITAL, LLC
CIK 1569064
Shares
914.48K
Value
22.77M
Filed
Mar 31, 2024
| # | Institution | CIK | Shares | Est. Value | Period |
|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 1263508 | 10.89M | 46.15M | Jun 30, 2026 |
| 2 | FCPM III SERVICES B.V. | 2013410 | 3.47M | 14.71M | Jun 30, 2026 |
| 3 | ARMISTICE CAPITAL, LLC | 1601086 | 3.40M | 14.41M | Jun 30, 2026 |
| 4 | LONG FOCUS CAPITAL MANAGEMENT, LLC | 1602716 | 3.31M | 14.04M | Jun 30, 2026 |
| 5 | PARADIGM BIOCAPITAL ADVISORS LP | 1855655 | 3.25M | 80.84M | Mar 31, 2024 |
| 6 | WESTFIELD CAPITAL MANAGEMENT CO LP | 1177719 | 3.02M | 21.35M | Dec 31, 2025 |
| 7 | ACADIAN ASSET MANAGEMENT LLC | 916542 | 1.97M | 8.32K | Jun 30, 2026 |
| 8 | SIREN, L.L.C. | 2005245 | 1.56M | 7.24M | Mar 31, 2026 |
| 9 | RENAISSANCE TECHNOLOGIES LLC | 1037389 | 1.53M | 6.50M | Jun 30, 2026 |
| 10 | GSK PLC | 1131399 | 1.53M | 6.49M | Jun 30, 2026 |
| 11 | BRAIDWELL LP | 1920938 | 1.29M | 25.91M | Sep 30, 2023 |
| 12 | DEEP TRACK CAPITAL, LP | 1856083 | 1.20M | 8.36M | Jun 30, 2025 |
| 13 | CANDRIAM S.C.A. | 1537014 | 1.19M | 8.44M | Dec 31, 2025 |
| 14 | PRINCIPAL FINANCIAL GROUP INC | 1126328 | 1.17M | 5.45M | Mar 31, 2026 |
| 15 | RA CAPITAL MANAGEMENT, L.P. | 1346824 | 1.09M | 9.28M | Mar 31, 2025 |
| 16 | POLAR CAPITAL HOLDINGS PLC | 1837309 | 1M | 22.69M | Sep 30, 2024 |
| 17 | TYBOURNE CAPITAL MANAGEMENT (HK) LTD | 1553936 | 993.74K | 6.91M | Jun 30, 2025 |
| 18 | FIRST LIGHT ASSET MANAGEMENT, LLC | 1600004 | 967.01K | 21.88M | Sep 30, 2024 |
| 19 | CAMBER CAPITAL MANAGEMENT LP | 1444043 | 915K | 20.71K | Sep 30, 2024 |
| 20 | MONTANOVA CAPITAL, LLC | 1569064 | 914.48K | 22.77M | Mar 31, 2024 |
Data sourced from SEC Form 13F institutional holdings reports. Positions reflect the most recent filing per institution.