DOYLESTOWN, PA
APREA THERAPEUTICS, INC.APRE— Latest position per institution from SEC 13F filings
15
Institutional holders
3.45M
Total shares held
4M
Estimated value
172.62K
Avg. position size
AIGH CAPITAL MANAGEMENT LLC
CIK 1835943
Shares
1.02M
Value
814.77K
Filed
Jun 30, 2026
VESTAL POINT CAPITAL, LP
CIK 1974915
Shares
350K
Value
280.81K
Filed
Jun 30, 2026
MURCHINSON LTD.
CIK 1838556
Shares
340.14K
Value
290.14K
Filed
Dec 31, 2025
SPHERA FUNDS MANAGEMENT LTD.
CIK 1496201
Shares
270K
Value
216.62K
Filed
Jun 30, 2026
NANTAHALA CAPITAL MANAGEMENT, LLC
CIK 1472322
Shares
205.76K
Value
165.08K
Filed
Jun 30, 2026
ALTIUM CAPITAL MANAGEMENT LLC
CIK 1746382
Shares
137.20K
Value
558.39K
Filed
Jun 30, 2024
DAFNA CAPITAL MANAGEMENT LLC
CIK 1389933
Shares
137.17K
Value
202.33K
Filed
Sep 30, 2025
DRW SECURITIES, LLC
CIK 1481986
Shares
120.65K
Value
102.92K
Filed
Dec 31, 2025
SIO CAPITAL MANAGEMENT, LLC
CIK 1482416
Shares
112.22K
Value
165.53K
Filed
Sep 30, 2025
RENAISSANCE TECHNOLOGIES LLC
CIK 1037389
Shares
105.80K
Value
84.88K
Filed
Jun 30, 2026
STONEPINE CAPITAL MANAGEMENT, LLC
CIK 1440771
Shares
102.24K
Value
14.40K
Filed
Mar 31, 2025
WORTH VENTURE PARTNERS, LLC
CIK 1696778
Shares
87.17K
Value
409.69K
Filed
Dec 31, 2023
WALLEYE CAPITAL LLC
CIK 1758720
Shares
80K
Value
376K
Filed
Dec 31, 2023
GEODE CAPITAL MANAGEMENT, LLC
CIK 1214717
Shares
74.87K
Value
60.07K
Filed
Jun 30, 2026
SCIENTECH RESEARCH LLC
CIK 2011556
Shares
60.28K
Value
45.99K
Filed
Mar 31, 2026
CITADEL ADVISORS LLC
CIK 1423053
Shares
58.60K
Value
47.02K
Filed
Jun 30, 2026
VANGUARD GROUP INC
CIK 102909
Shares
58.09K
Value
49.55K
Filed
Dec 31, 2025
JANE STREET GROUP, LLC
CIK 1595888
Shares
46.62K
Value
39.77K
Filed
Dec 31, 2025
BNP PARIBAS FINANCIAL MARKETS
CIK 1166588
Shares
45.21K
Value
36.27K
Filed
Jun 30, 2026
DIADEMA PARTNERS LP
CIK 2026172
Shares
44.91K
Value
36.03K
Filed
Jun 30, 2026
| # | Institution | CIK | Shares | Est. Value | Period |
|---|---|---|---|---|---|
| 1 | AIGH CAPITAL MANAGEMENT LLC | 1835943 | 1.02M | 814.77K | Jun 30, 2026 |
| 2 | VESTAL POINT CAPITAL, LP | 1974915 | 350K | 280.81K | Jun 30, 2026 |
| 3 | MURCHINSON LTD. | 1838556 | 340.14K | 290.14K | Dec 31, 2025 |
| 4 | SPHERA FUNDS MANAGEMENT LTD. | 1496201 | 270K | 216.62K | Jun 30, 2026 |
| 5 | NANTAHALA CAPITAL MANAGEMENT, LLC | 1472322 | 205.76K | 165.08K | Jun 30, 2026 |
| 6 | ALTIUM CAPITAL MANAGEMENT LLC | 1746382 | 137.20K | 558.39K | Jun 30, 2024 |
| 7 | DAFNA CAPITAL MANAGEMENT LLC | 1389933 | 137.17K | 202.33K | Sep 30, 2025 |
| 8 | DRW SECURITIES, LLC | 1481986 | 120.65K | 102.92K | Dec 31, 2025 |
| 9 | SIO CAPITAL MANAGEMENT, LLC | 1482416 | 112.22K | 165.53K | Sep 30, 2025 |
| 10 | RENAISSANCE TECHNOLOGIES LLC | 1037389 | 105.80K | 84.88K | Jun 30, 2026 |
| 11 | STONEPINE CAPITAL MANAGEMENT, LLC | 1440771 | 102.24K | 14.40K | Mar 31, 2025 |
| 12 | WORTH VENTURE PARTNERS, LLC | 1696778 | 87.17K | 409.69K | Dec 31, 2023 |
| 13 | WALLEYE CAPITAL LLC | 1758720 | 80K | 376K | Dec 31, 2023 |
| 14 | GEODE CAPITAL MANAGEMENT, LLC | 1214717 | 74.87K | 60.07K | Jun 30, 2026 |
| 15 | SCIENTECH RESEARCH LLC | 2011556 | 60.28K | 45.99K | Mar 31, 2026 |
| 16 | CITADEL ADVISORS LLC | 1423053 | 58.60K | 47.02K | Jun 30, 2026 |
| 17 | VANGUARD GROUP INC | 102909 | 58.09K | 49.55K | Dec 31, 2025 |
| 18 | JANE STREET GROUP, LLC | 1595888 | 46.62K | 39.77K | Dec 31, 2025 |
| 19 | BNP PARIBAS FINANCIAL MARKETS | 1166588 | 45.21K | 36.27K | Jun 30, 2026 |
| 20 | DIADEMA PARTNERS LP | 2026172 | 44.91K | 36.03K | Jun 30, 2026 |
Data sourced from SEC Form 13F institutional holdings reports. Positions reflect the most recent filing per institution.