VAN HOUTE HANS (Chief Financial Officer) sold 6.7% of their position (3.13K shares) of NURIX THERAPEUTICS, INC. on the open market

Open‑market sale worth $40.1K — a moderate reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 1 sale

VAN HOUTE HANS

Filed: 10/30/2025ACC: 0001817217-25-000003

InsiderVAN HOUTE HANSCIK 1817217

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IssuerNURIX THERAPEUTICS, INC.CIK 1549595

Officer· Chief Financial Officer

Since Jul 2020

-3.13K

Net shares

Net seller

$40.1K

Total sold

Open market trades

0B · 1S

Total transactions

11.49K acquired · 14.62K disposed

Non-Derivative Transactions5

Common Stock

Direct

M · Option Exercise

+2.89K

Price / share

—

Trade value

—

% of position

8.1%

10/30/2025

35.51K→38.40K

Common Stock

Direct

M · Option Exercise

+2K

Price / share

—

Trade value

—

% of position

5.2%

10/30/2025

38.40K→40.40K

Common Stock

Direct

M · Option Exercise

+3.75K

Price / share

—

Trade value

—

% of position

9.3%

10/30/2025

40.40K→44.15K

Common Stock

Direct

M · Option Exercise

+2.86K

Price / share

—

Trade value

—

% of position

6.5%

10/30/2025

44.15K→47.01K

Common Stock

Direct

S · Sale

−3.13K

Price / share

$12.80

Trade value

$40.05K

% of position

6.7%

10/30/2025

47.01K→43.88K

Total

Net shares

+8.36K

Net value

-$40.05K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	10/30/2025	M · Option Exercise	+2.89K	—	—	8.1%	35.51K	38.40K
Common Stock Direct	10/30/2025	M · Option Exercise	+2K	—	—	5.2%	38.40K	40.40K
Common Stock Direct	10/30/2025	M · Option Exercise	+3.75K	—	—	9.3%	40.40K	44.15K
Common Stock Direct	10/30/2025	M · Option Exercise	+2.86K	—	—	6.5%	44.15K	47.01K
Common Stock Direct	10/30/2025	S · Sale	−3.13K	$12.80	$40.05K	6.7%	47.01K	43.88K
Total			+8.36K		-$40.05K

Derivative Transactions4

Restricted Stock Units

Direct

M · Option Exercise

Converts to

Common Stock

2.89K shares

−2.89K

Strike price

Held after

2.89K

Exercisable

—

10/30/2025

Restricted Stock Units

Direct

M · Option Exercise

Converts to

Common Stock

2K shares

−2K

Strike price

Held after

Exercisable

—

10/30/2025

Restricted Stock Units

Direct

M · Option Exercise

Converts to

Common Stock

3.75K shares

−3.75K

Strike price

Held after

22.50K

Exercisable

—

10/30/2025

Restricted Stock Units

Direct

M · Option Exercise

Converts to

Common Stock

2.86K shares

−2.86K

Strike price

Held after

28.58K

Exercisable

—

10/30/2025

Security	Converts To	Date	Type	Shares	Exercisable	Held After
Restricted Stock Units Direct	Common Stock2.89K shares	10/30/2025	M · Option Exercise	−2.89K	—	2.89K
Restricted Stock Units Direct	Common Stock2K shares	10/30/2025	M · Option Exercise	−2K	—	4K
Restricted Stock Units Direct	Common Stock3.75K shares	10/30/2025	M · Option Exercise	−3.75K	—	22.50K
Restricted Stock Units Direct	Common Stock2.86K shares	10/30/2025	M · Option Exercise	−2.86K	—	28.58K