Filed: 5/14/2026ACC: 0002050194-26-000004
📋 What this filing means
SPRUCE STREET CAPITAL LP filed this quarterly 13F‑HR report disclosing 28 equity positions with a total reported market value of $415.94M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
28
Positions
$415.94M
Total AUM (reported)
41.06M
Total Shares
Allocation by class
COM$232.80M56.0%
COM SHS$62.76M15.1%
COM NEW$47.95M11.5%
ORD SHS CL A$36.65M8.8%
SPONSORED ADS$19.46M4.7%
SHS$11.24M2.7%
USD CL A ORD SHS$5.08M1.2%
Portfolio Concentration
Top 3$113.29M27.2%
4–10$160.41M38.6%
11–25$130.49M31.4%
Rest$11.75M2.8%
Top 3 weight
27.2%
Top 10 weight
65.8%
Voting Authority Distribution
Total shares with voting rights: 41.06M
Sole
Full voting authority
41.06M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole28
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings28
Rows:
RELMADA THERAPEUTICS INC
SOLEShares6.26M
TypeSH
Market value$43.00M
10.34%
Sole
6.26M
Shared
0.00
None
0.00
KINIKSA PHARMACEUTICALS I
SOLEShares761.06K
TypeSH
Market value$36.65M
8.81%
Sole
761.06K
Shared
0.00
None
0.00
LB PHARMACEUTICALS INC
SOLEShares1.38M
TypeSH
Market value$33.64M
8.09%
Sole
1.38M
Shared
0.00
None
0.00
DIANTHUS THERAPEUTICS IN
SOLEShares373.27K
TypeSH
Market value$31.33M
7.53%
Sole
373.27K
Shared
0.00
None
0.00
RELAY THERAPEUTICS INC
SOLEShares2.98M
TypeSH
Market value$29.69M
7.14%
Sole
2.98M
Shared
0.00
None
0.00
ALTO NEUROSCIENCE INC
SOLEShares1.33M
TypeSH
Market value$29.12M
7.00%
Sole
1.33M
Shared
0.00
None
0.00
CENTESSA PHARMACEUTICALS
SOLEShares489.85K
TypeSH
Market value$19.46M
4.68%
Sole
489.85K
Shared
0.00
None
0.00
SAVARA INC
SOLEShares3.38M
TypeSH
Market value$18.47M
4.44%
Sole
3.38M
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS
SOLEShares897.68K
TypeSH
Market value$18.07M
4.34%
Sole
897.68K
Shared
0.00
None
0.00
VAXCYTE INC
SOLEShares245.71K
TypeSH
Market value$14.28M
3.43%
Sole
245.71K
Shared
0.00
None
0.00
ENLIVEN THERAPEUTICS INC
SOLEShares329.01K
TypeSH
Market value$12.90M
3.10%
Sole
329.01K
Shared
0.00
None
0.00
SURROZEN INC COM NEW
SOLEShares432.04K
TypeSH
Market value$12.59M
3.03%
Sole
432.04K
Shared
0.00
None
0.00
ENANTA PHARMACEUTICALS I
SOLEShares932.60K
TypeSH
Market value$11.78M
2.83%
Sole
932.60K
Shared
0.00
None
0.00
ALKERMES PLC
SOLEShares317.99K
TypeSH
Market value$11.24M
2.70%
Sole
317.99K
Shared
0.00
None
0.00
PERSPECTIVE THERAPEUTICS
SOLEShares2.63M
TypeSH
Market value$10.96M
2.63%
Sole
2.63M
Shared
0.00
None
0.00
MINERVA NEUROSCIENC
SOLEShares1.66M
TypeSH
Market value$9.97M
2.40%
Sole
1.66M
Shared
0.00
None
0.00
CENTURY THERAPEUTICS
SOLEShares4.06M
TypeSH
Market value$9.17M
2.21%
Sole
4.06M
Shared
0.00
None
0.00
ALUMIS INC
SOLEShares392.57K
TypeSH
Market value$8.65M
2.08%
Sole
392.57K
Shared
0.00
None
0.00
SAB BIOTHERAPEUTICS IN
SOLEShares2.20M
TypeSH
Market value$8.42M
2.02%
Sole
2.20M
Shared
0.00
None
0.00
ERASCA INC
SOLEShares422.54K
TypeSH
Market value$6.84M
1.64%
Sole
422.54K
Shared
0.00
None
0.00
INHIBIKASE THERAPEUTI
SOLEShares3.58M
TypeSH
Market value$6.02M
1.45%
Sole
3.58M
Shared
0.00
None
0.00
MAZE THERAPEUTICS INC
SOLEShares200K
TypeSH
Market value$5.97M
1.44%
Sole
200K
Shared
0.00
None
0.00
AN2 THERAPEUTICS INC
SOLEShares1.66M
TypeSH
Market value$5.58M
1.34%
Sole
1.66M
Shared
0.00
None
0.00
LEXEO THERAPEUTICS INC
SOLEShares928.59K
TypeSH
Market value$5.33M
1.28%
Sole
928.59K
Shared
0.00
None
0.00
HELIX ACQUISITION CORP III
SOLEShares500K
TypeSH
Market value$5.08M
1.22%
Sole
500K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
RELMADA THERAPEUTICS INCSOLE | COM | 6.26M | SH | $43.00M 10.34% | 6.26M | 0.00 | 0.00 |
KINIKSA PHARMACEUTICALS ISOLE | ORD SHS CL A | 761.06K | SH | $36.65M 8.81% | 761.06K | 0.00 | 0.00 |
LB PHARMACEUTICALS INCSOLE | COM SHS | 1.38M | SH | $33.64M 8.09% | 1.38M | 0.00 | 0.00 |
DIANTHUS THERAPEUTICS INSOLE | COM | 373.27K | SH | $31.33M 7.53% | 373.27K | 0.00 | 0.00 |
RELAY THERAPEUTICS INCSOLE | COM | 2.98M | SH | $29.69M 7.14% | 2.98M | 0.00 | 0.00 |
ALTO NEUROSCIENCE INCSOLE | COM SHS | 1.33M | SH | $29.12M 7.00% | 1.33M | 0.00 | 0.00 |
CENTESSA PHARMACEUTICALSSOLE | SPONSORED ADS | 489.85K | SH | $19.46M 4.68% | 489.85K | 0.00 | 0.00 |
SAVARA INCSOLE | COM | 3.38M | SH | $18.47M 4.44% | 3.38M | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALSSOLE | COM | 897.68K | SH | $18.07M 4.34% | 897.68K | 0.00 | 0.00 |
VAXCYTE INCSOLE | COM | 245.71K | SH | $14.28M 3.43% | 245.71K | 0.00 | 0.00 |
ENLIVEN THERAPEUTICS INCSOLE | COM | 329.01K | SH | $12.90M 3.10% | 329.01K | 0.00 | 0.00 |
SURROZEN INC COM NEWSOLE | COM NEW | 432.04K | SH | $12.59M 3.03% | 432.04K | 0.00 | 0.00 |
ENANTA PHARMACEUTICALS ISOLE | COM | 932.60K | SH | $11.78M 2.83% | 932.60K | 0.00 | 0.00 |
ALKERMES PLCSOLE | SHS | 317.99K | SH | $11.24M 2.70% | 317.99K | 0.00 | 0.00 |
PERSPECTIVE THERAPEUTICSSOLE | COM NEW | 2.63M | SH | $10.96M 2.63% | 2.63M | 0.00 | 0.00 |
MINERVA NEUROSCIENCSOLE | COM NEW | 1.66M | SH | $9.97M 2.40% | 1.66M | 0.00 | 0.00 |
CENTURY THERAPEUTICSSOLE | COM | 4.06M | SH | $9.17M 2.21% | 4.06M | 0.00 | 0.00 |
ALUMIS INCSOLE | COM | 392.57K | SH | $8.65M 2.08% | 392.57K | 0.00 | 0.00 |
SAB BIOTHERAPEUTICS INSOLE | COM NEW | 2.20M | SH | $8.42M 2.02% | 2.20M | 0.00 | 0.00 |
ERASCA INCSOLE | COM | 422.54K | SH | $6.84M 1.64% | 422.54K | 0.00 | 0.00 |
INHIBIKASE THERAPEUTISOLE | COM NEW | 3.58M | SH | $6.02M 1.45% | 3.58M | 0.00 | 0.00 |
MAZE THERAPEUTICS INCSOLE | COM | 200K | SH | $5.97M 1.44% | 200K | 0.00 | 0.00 |
AN2 THERAPEUTICS INCSOLE | COM | 1.66M | SH | $5.58M 1.34% | 1.66M | 0.00 | 0.00 |
LEXEO THERAPEUTICS INCSOLE | COM | 928.59K | SH | $5.33M 1.28% | 928.59K | 0.00 | 0.00 |
HELIX ACQUISITION CORP IIISOLE | USD CL A ORD SHS | 500K | SH | $5.08M 1.22% | 500K | 0.00 | 0.00 |
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