SILVER ANDREW JACOB

Filed: 10/21/2026ACC: 0001193125-26-428002

InsiderSILVER ANDREW JACOBCIK 2158786

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IssuerCRISPR THERAPEUTICS AGCIK 1674416

Officer· Chief Financial Officer

Since Oct 2026

0.00

Baseline shares

0.00

Direct ownership

0 positions

154.27K

Derivative underlying

22 instruments

Security positions

All direct

Non-Derivative Holdings0

No non-derivative holdings reported

Derivative Holdings22

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

1.80K

Shares owned

N/A

Exercise price

86.75

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

18.73K

Shares owned

N/A

Exercise price

42.12

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

2.37K

Shares owned

N/A

Exercise price

61.65

Expiration

—

Exercise window

—

Restricted Stock Units

Direct

Underlying security

Common Shares

Underlying shares

15K

Shares owned

N/A

Exercise price

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

3.77K

Shares owned

N/A

Exercise price

44.31

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

1.40K

Shares owned

N/A

Exercise price

39.00

Expiration

—

Exercise window

—

Restricted Stock Units

Direct

Underlying security

Common Shares

Underlying shares

10K

Shares owned

N/A

Exercise price

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

1.97K

Shares owned

N/A

Exercise price

97.00

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

3.84K

Shares owned

N/A

Exercise price

58.29

Expiration

—

Exercise window

—

Restricted Stock Units

Direct

Underlying security

Common Shares

Underlying shares

15K

Shares owned

N/A

Exercise price

Expiration

—

Exercise window

—

Restricted Stock Units

Direct

Underlying security

Common Shares

Underlying shares

12K

Shares owned

N/A

Exercise price

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

2.81K

Shares owned

N/A

Exercise price

44.67

Expiration

—

Exercise window

—

Stock Option ( Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

3.77K

Shares owned

N/A

Exercise price

49.00

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

6.94K

Shares owned

N/A

Exercise price

67.74

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

9.04K

Shares owned

N/A

Exercise price

72.94

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

4.52K

Shares owned

N/A

Exercise price

133.88

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

4.89K

Shares owned

N/A

Exercise price

35.59

Expiration

—

Exercise window

—

Restricted Stock Units

Direct

Underlying security

Common Shares

Underlying shares

3.39K

Shares owned

N/A

Exercise price

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

8.43K

Shares owned

N/A

Exercise price

43.22

Expiration

—

Exercise window

—

Restricted Stock Units

Direct

Underlying security

Common Shares

Underlying shares

1.30K

Shares owned

N/A

Exercise price

Expiration

—

Exercise window

—

Restricted Stock Units

Direct

Underlying security

Common Shares

Underlying shares

8.44K

Shares owned

N/A

Exercise price

Expiration

—

Exercise window

—

Stock Option (Right to Buy)

Direct

Underlying security

Common Shares

Underlying shares

14.87K

Shares owned

N/A

Exercise price

46.24

Expiration

—

Exercise window

—

Total

Underlying

154.27K

Owned

0.00

Security	Underlying	Exercise Price	Exercise Window	Expiration	Underlying Shares	Shares Owned
Stock Option (Right to Buy) Direct	Common Shares	86.75	—	—	1.80K	N/A
Stock Option (Right to Buy) Direct	Common Shares	42.12	—	—	18.73K	N/A
Stock Option (Right to Buy) Direct	Common Shares	61.65	—	—	2.37K	N/A
Restricted Stock Units Direct	Common Shares		—	—	15K	N/A
Stock Option (Right to Buy) Direct	Common Shares	44.31	—	—	3.77K	N/A
Stock Option (Right to Buy) Direct	Common Shares	39.00	—	—	1.40K	N/A
Restricted Stock Units Direct	Common Shares		—	—	10K	N/A
Stock Option (Right to Buy) Direct	Common Shares	97.00	—	—	1.97K	N/A
Stock Option (Right to Buy) Direct	Common Shares	58.29	—	—	3.84K	N/A
Restricted Stock Units Direct	Common Shares		—	—	15K	N/A
Restricted Stock Units Direct	Common Shares		—	—	12K	N/A
Stock Option (Right to Buy) Direct	Common Shares	44.67	—	—	2.81K	N/A
Stock Option ( Right to Buy) Direct	Common Shares	49.00	—	—	3.77K	N/A
Stock Option (Right to Buy) Direct	Common Shares	67.74	—	—	6.94K	N/A
Stock Option (Right to Buy) Direct	Common Shares	72.94	—	—	9.04K	N/A
Stock Option (Right to Buy) Direct	Common Shares	133.88	—	—	4.52K	N/A
Stock Option (Right to Buy) Direct	Common Shares	35.59	—	—	4.89K	N/A
Restricted Stock Units Direct	Common Shares		—	—	3.39K	N/A
Stock Option (Right to Buy) Direct	Common Shares	43.22	—	—	8.43K	N/A
Restricted Stock Units Direct	Common Shares		—	—	1.30K	N/A
Restricted Stock Units Direct	Common Shares		—	—	8.44K	N/A
Stock Option (Right to Buy) Direct	Common Shares	46.24	—	—	14.87K	N/A
Total					154.27K	0.00