SHULMAN JOSEPH (Chief Technical Officer) sold 62.9% of their position (14.44K shares) of RHYTHM PHARMACEUTICALS, INC. on the open market

Open‑market sale worth $1.62M — a major position exit. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 3 sales

SHULMAN JOSEPH

Filed: 10/20/2025ACC: 0001104659-25-100851

InsiderSHULMAN JOSEPHCIK 1909855

→

IssuerRHYTHM PHARMACEUTICALS, INC.CIK 1649904

Officer· Chief Technical Officer

Since Feb 2022

-14.44K

Net shares

Net seller

$1.62M

Total sold

Open market trades

0B · 3S

Total transactions

14.44K acquired · 28.87K disposed

Non-Derivative Transactions5

Common Stock

Direct

M · Option Exercise

+2.09K

Price / share

$27.35

Trade value

$57.24K

% of position

24.6%

10/16/2025

8.51K→10.60K

Common Stock

Direct

M · Option Exercise

+12.34K

Price / share

$30.66

Trade value

$378.47K

% of position

116.4%

10/16/2025

10.60K→22.95K

Common Stock

Direct

S · Sale

−2.69K

Price / share

$110.95

Trade value

$298.78K

% of position

11.7%

10/16/2025

22.95K→20.25K

Common Stock

Direct

S · Sale

−8.33K

Price / share

$112.06

Trade value

$933.65K

% of position

41.1%

10/16/2025

20.25K→11.92K

Common Stock

Direct

S · Sale

−3.41K

Price / share

$112.81

Trade value

$384.91K

% of position

28.6%

10/16/2025

11.92K→8.51K

Total

Net shares

+0.00

Net value

-$1.18M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	10/16/2025	M · Option Exercise	+2.09K	$27.35	$57.24K	24.6%	8.51K	10.60K
Common Stock Direct	10/16/2025	M · Option Exercise	+12.34K	$30.66	$378.47K	116.4%	10.60K	22.95K
Common Stock Direct	10/16/2025	S · Sale	−2.69K	$110.95	$298.78K	11.7%	22.95K	20.25K
Common Stock Direct	10/16/2025	S · Sale	−8.33K	$112.06	$933.65K	41.1%	20.25K	11.92K
Common Stock Direct	10/16/2025	S · Sale	−3.41K	$112.81	$384.91K	28.6%	11.92K	8.51K
Total			+0.00		-$1.18M

Derivative Transactions2

Stock Options (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.09K shares

−2.09K

Strike price

27.35

Held after

14.66K

Exercisable

—

10/16/2025

Stock Options (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

12.34K shares

−12.34K

Strike price

30.66

Held after

10.47K

Exercisable

—

10/16/2025

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Stock Options (Right to Buy) Direct	Common Stock2.09K shares	10/16/2025	M · Option Exercise	−2.09K	27.35	—	14.66K
Stock Options (Right to Buy) Direct	Common Stock12.34K shares	10/16/2025	M · Option Exercise	−12.34K	30.66	—	10.47K