SHETTY RESHMA P. (President, COO & Founder) sold 10.4% of their position (41.17K shares) of GINKGO BIOWORKS HOLDINGS, INC. on the open market

Open‑market sale worth $417.6K — a moderate reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 2 sales

SHETTY RESHMA P.

Filed: 10/21/2026ACC: 0001628280-26-066704

InsiderSHETTY RESHMA P.CIK 1873523

→

IssuerGINKGO BIOWORKS HOLDINGS, INC.CIK 1830214

DirectorOfficer10% Owner· President, COO & Founder

Since Sep 2021

-41.17K

Net shares

Net seller

$417.6K

Total sold

Open market trades

0B · 2S

Total transactions

76.46K acquired · 117.63K disposed

Non-Derivative Transactions6

Class A Common Stock

Direct

M · Option Exercise

+29.28K

Price / share

—

Trade value

—

% of position

6.7%

10/16/2026

436.42K→465.70K

Class A Common Stock

Direct

M · Option Exercise

+10.62K

Price / share

—

Trade value

—

% of position

2.3%

10/16/2026

465.70K→476.32K

Class A Common Stock

Indirect

M · Option Exercise

+26.80K

Price / share

—

Trade value

—

% of position

7.9%

10/16/2026

338.57K→365.37K

Class A Common Stock

Indirect

M · Option Exercise

+9.76K

Price / share

—

Trade value

—

% of position

2.7%

10/16/2026

365.37K→375.13K

Class A Common Stock

Direct

S · Sale

−22.37K

Price / share

$10.14

Trade value

$226.89K

% of position

4.7%

10/19/2026

476.32K→453.95K

Class A Common Stock

Indirect

S · Sale

−18.80K

Price / share

$10.14

Trade value

$190.72K

% of position

5.0%

10/19/2026

375.13K→356.33K

Total

Net shares

+35.29K

Net value

-$417.61K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Class A Common Stock Direct	10/16/2026	M · Option Exercise	+29.28K	—	—	6.7%	436.42K	465.70K
Class A Common Stock Direct	10/16/2026	M · Option Exercise	+10.62K	—	—	2.3%	465.70K	476.32K
Class A Common Stock Indirect	10/16/2026	M · Option Exercise	+26.80K	—	—	7.9%	338.57K	365.37K
Class A Common Stock Indirect	10/16/2026	M · Option Exercise	+9.76K	—	—	2.7%	365.37K	375.13K
Class A Common Stock Direct	10/19/2026	S · Sale	−22.37K	$10.14	$226.89K	4.7%	476.32K	453.95K
Class A Common Stock Indirect	10/19/2026	S · Sale	−18.80K	$10.14	$190.72K	5.0%	375.13K	356.33K
Total			+35.29K		-$417.61K

Derivative Transactions4

Restricted Stock Units

Direct

M · Option Exercise

Converts to

Class A Common Stock

29.28K shares

−29.28K

Strike price

Held after

9.76K

Exercisable

—

10/16/2026

Restricted Stock Units

Direct

M · Option Exercise

Converts to

Class A Common Stock

10.62K shares

−10.62K

Strike price

Held after

116.80K

Exercisable

—

10/16/2026

Restricted Stock Units

Indirect

M · Option Exercise

Converts to

Class A Common Stock

26.80K shares

−26.80K

Strike price

Held after

8.93K

Exercisable

—

10/16/2026

Restricted Stock Units

Indirect

M · Option Exercise

Converts to

Class A Common Stock

9.76K shares

−9.76K

Strike price

Held after

107.37K

Exercisable

—

10/16/2026

Security	Converts To	Date	Type	Shares	Exercisable	Held After
Restricted Stock Units Direct	Class A Common Stock29.28K shares	10/16/2026	M · Option Exercise	−29.28K	—	9.76K
Restricted Stock Units Direct	Class A Common Stock10.62K shares	10/16/2026	M · Option Exercise	−10.62K	—	116.80K
Restricted Stock Units Indirect	Class A Common Stock26.80K shares	10/16/2026	M · Option Exercise	−26.80K	—	8.93K
Restricted Stock Units Indirect	Class A Common Stock9.76K shares	10/16/2026	M · Option Exercise	−9.76K	—	107.37K