Filed: 5/15/2025ACC: 0001493215-25-000003
📋 What this filing means
RTW INVESTMENTS, LP filed this quarterly 13F‑HR report disclosing 68 equity positions with a total reported market value of $6.54B. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
68
Positions
$6.54B
Total AUM (reported)
224.93M
Total Shares
Allocation by class
COM$4.60B70.4%
SPONSORED ADR$398.62M6.1%
SHS$315.96M4.8%
COM NEW$296.15M4.5%
COM PAR $.01$229.98M3.5%
SPONSORED ADS$197.43M3.0%
ADS$144.49M2.2%
Portfolio Concentration
Top 3$1.44B22.0%
4–10$2.00B30.6%
11–25$2.14B32.7%
Rest$957.70M14.6%
Top 3 weight
22.0%
Top 10 weight
52.7%
Voting Authority Distribution
Total shares with voting rights: 224.93M
Sole
Full voting authority
224.93M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole68
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings68
Rows:
MADRIGAL PHARMACEUTICALS INC
SOLEShares1.99M
TypeSH
Market value$660.37M
10.10%
Sole
1.99M
Shared
0.00
None
0.00
ARGENX SE
SOLEShares673.50K
TypeSH
Market value$398.62M
6.10%
Sole
673.50K
Shared
0.00
None
0.00
PTC THERAPEUTICS INC
SOLEShares7.48M
TypeSH
Market value$381.34M
5.83%
Sole
7.48M
Shared
0.00
None
0.00
NATERA INC
SOLEShares2.59M
TypeSH
Market value$366.75M
5.61%
Sole
2.59M
Shared
0.00
None
0.00
AXSOME THERAPEUTICS INC
SOLEShares2.92M
TypeSH
Market value$340.88M
5.21%
Sole
2.92M
Shared
0.00
None
0.00
AKERO THERAPEUTICS INC
SOLEShares7.42M
TypeSH
Market value$300.33M
4.59%
Sole
7.42M
Shared
0.00
None
0.00
PROTAGONIST THERAPEUTICS INC
SOLEShares5.72M
TypeSH
Market value$276.59M
4.23%
Sole
5.72M
Shared
0.00
None
0.00
AVIDITY BIOSCIENCES INC
SOLEShares8.75M
TypeSH
Market value$258.21M
3.95%
Sole
8.75M
Shared
0.00
None
0.00
PENUMBRA INC
SOLEShares862.77K
TypeSH
Market value$230.71M
3.53%
Sole
862.77K
Shared
0.00
None
0.00
INSMED INC
SOLEShares3.01M
TypeSH
Market value$229.98M
3.52%
Sole
3.01M
Shared
0.00
None
0.00
ALKERMES PLC
SOLEShares6.88M
TypeSH
Market value$227.33M
3.48%
Sole
6.88M
Shared
0.00
None
0.00
STRYKER CORPORATION
SOLEShares590.22K
TypeSH
Market value$219.71M
3.36%
Sole
590.22K
Shared
0.00
None
0.00
VERONA PHARMA PLC
SOLEShares2.85M
TypeSH
Market value$180.87M
2.77%
Sole
2.85M
Shared
0.00
None
0.00
MERUS N V
SOLEShares4.17M
TypeSH
Market value$175.49M
2.68%
Sole
4.17M
Shared
0.00
None
0.00
TARSUS PHARMACEUTICALS INC
SOLEShares3.32M
TypeSH
Market value$170.34M
2.61%
Sole
3.32M
Shared
0.00
None
0.00
IMMUNOCORE HLDGS PLC
SOLEShares4.87M
TypeSH
Market value$144.49M
2.21%
Sole
4.87M
Shared
0.00
None
0.00
ACADIA PHARMACEUTICALS INC
SOLEShares8.54M
TypeSH
Market value$141.85M
2.17%
Sole
8.54M
Shared
0.00
None
0.00
ROCKET PHARMACEUTICALS INC
SOLEShares17.69M
TypeSH
Market value$117.98M
1.80%
Sole
17.69M
Shared
0.00
None
0.00
RADNET INC
SOLEShares2.32M
TypeSH
Market value$115.23M
1.76%
Sole
2.32M
Shared
0.00
None
0.00
MASIMO CORP
SOLEShares683.29K
TypeSH
Market value$113.84M
1.74%
Sole
683.29K
Shared
0.00
None
0.00
ZAI LAB LTD
SOLEShares3.14M
TypeSH
Market value$113.36M
1.73%
Sole
3.14M
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares2.72M
TypeSH
Market value$109.36M
1.67%
Sole
2.72M
Shared
0.00
None
0.00
ESTABLISHMENT LABS HLDGS INC
SOLEShares2.58M
TypeSH
Market value$105.44M
1.61%
Sole
2.58M
Shared
0.00
None
0.00
APOGEE THERAPEUTICS INC
SOLEShares2.71M
TypeSH
Market value$101.32M
1.55%
Sole
2.71M
Shared
0.00
None
0.00
INTUITIVE SURGICAL INC
SOLEShares202.46K
TypeSH
Market value$100.27M
1.53%
Sole
202.46K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
MADRIGAL PHARMACEUTICALS INCSOLE | COM | 1.99M | SH | $660.37M 10.10% | 1.99M | 0.00 | 0.00 |
ARGENX SESOLE | SPONSORED ADR | 673.50K | SH | $398.62M 6.10% | 673.50K | 0.00 | 0.00 |
PTC THERAPEUTICS INCSOLE | COM | 7.48M | SH | $381.34M 5.83% | 7.48M | 0.00 | 0.00 |
NATERA INCSOLE | COM | 2.59M | SH | $366.75M 5.61% | 2.59M | 0.00 | 0.00 |
AXSOME THERAPEUTICS INCSOLE | COM | 2.92M | SH | $340.88M 5.21% | 2.92M | 0.00 | 0.00 |
AKERO THERAPEUTICS INCSOLE | COM | 7.42M | SH | $300.33M 4.59% | 7.42M | 0.00 | 0.00 |
PROTAGONIST THERAPEUTICS INCSOLE | COM | 5.72M | SH | $276.59M 4.23% | 5.72M | 0.00 | 0.00 |
AVIDITY BIOSCIENCES INCSOLE | COM | 8.75M | SH | $258.21M 3.95% | 8.75M | 0.00 | 0.00 |
PENUMBRA INCSOLE | COM | 862.77K | SH | $230.71M 3.53% | 862.77K | 0.00 | 0.00 |
INSMED INCSOLE | COM PAR $.01 | 3.01M | SH | $229.98M 3.52% | 3.01M | 0.00 | 0.00 |
ALKERMES PLCSOLE | SHS | 6.88M | SH | $227.33M 3.48% | 6.88M | 0.00 | 0.00 |
STRYKER CORPORATIONSOLE | COM | 590.22K | SH | $219.71M 3.36% | 590.22K | 0.00 | 0.00 |
VERONA PHARMA PLCSOLE | SPONSORED ADS | 2.85M | SH | $180.87M 2.77% | 2.85M | 0.00 | 0.00 |
MERUS N VSOLE | COM | 4.17M | SH | $175.49M 2.68% | 4.17M | 0.00 | 0.00 |
TARSUS PHARMACEUTICALS INCSOLE | COM | 3.32M | SH | $170.34M 2.61% | 3.32M | 0.00 | 0.00 |
IMMUNOCORE HLDGS PLCSOLE | ADS | 4.87M | SH | $144.49M 2.21% | 4.87M | 0.00 | 0.00 |
ACADIA PHARMACEUTICALS INCSOLE | COM | 8.54M | SH | $141.85M 2.17% | 8.54M | 0.00 | 0.00 |
ROCKET PHARMACEUTICALS INCSOLE | COM | 17.69M | SH | $117.98M 1.80% | 17.69M | 0.00 | 0.00 |
RADNET INCSOLE | COM | 2.32M | SH | $115.23M 1.76% | 2.32M | 0.00 | 0.00 |
MASIMO CORPSOLE | COM | 683.29K | SH | $113.84M 1.74% | 683.29K | 0.00 | 0.00 |
ZAI LAB LTDSOLE | ADR | 3.14M | SH | $113.36M 1.73% | 3.14M | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 2.72M | SH | $109.36M 1.67% | 2.72M | 0.00 | 0.00 |
ESTABLISHMENT LABS HLDGS INCSOLE | COM | 2.58M | SH | $105.44M 1.61% | 2.58M | 0.00 | 0.00 |
APOGEE THERAPEUTICS INCSOLE | COM | 2.71M | SH | $101.32M 1.55% | 2.71M | 0.00 | 0.00 |
INTUITIVE SURGICAL INCSOLE | COM NEW | 202.46K | SH | $100.27M 1.53% | 202.46K | 0.00 | 0.00 |
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