ROMANO KATHRYN (Chief Accounting Officer) sold 3.2% of their position (750.00 shares) of KRYSTAL BIOTECH, INC. on the open market

Open‑market sale worth $200.7K — a minor trim. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 1 sale

ROMANO KATHRYN

Filed: 3/3/2026ACC: 0001801385-26-000002

InsiderROMANO KATHRYNCIK 1801385

→

IssuerKRYSTAL BIOTECH, INC.CIK 1711279

Officer· Chief Accounting Officer

Since Jan 2020

+14.77K

Net shares

Net buyer

$1.17M

Total sold

Open market trades

0B · 1S

Total transactions

27.07K acquired · 12.30K disposed

Non-Derivative Transactions5

Common Stock

Direct

M · Option Exercise

+7.50K

Price / share

—

Trade value

—

% of position

40.4%

2/27/2026

18.57K→26.07K

Common Stock

Direct

F · Tax Withholding

−3.26K

Price / share

$275.64

Trade value

$899.14K

% of position

12.5%

2/27/2026

26.07K→22.81K

Common Stock

Direct

M · Option Exercise

+550.00

Price / share

—

Trade value

—

% of position

2.4%

2/27/2026

22.81K→23.36K

Common Stock

Direct

F · Tax Withholding

−240.00

Price / share

$275.64

Trade value

$66.15K

% of position

1.0%

2/27/2026

23.36K→23.12K

Common Stock

Direct

S · Sale

−750.00

Price / share

$267.60

Trade value

$200.70K

% of position

3.2%

3/2/2026

23.12K→22.37K

Total

Net shares

+3.80K

Net value

-$1.17M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	2/27/2026	M · Option Exercise	+7.50K	—	—	40.4%	18.57K	26.07K
Common Stock Direct	2/27/2026	F · Tax Withholding	−3.26K	$275.64	$899.14K	12.5%	26.07K	22.81K
Common Stock Direct	2/27/2026	M · Option Exercise	+550.00	—	—	2.4%	22.81K	23.36K
Common Stock Direct	2/27/2026	F · Tax Withholding	−240.00	$275.64	$66.15K	1.0%	23.36K	23.12K
Common Stock Direct	3/2/2026	S · Sale	−750.00	$267.60	$200.70K	3.2%	23.12K	22.37K
Total			+3.80K		-$1.17M

Derivative Transactions4

Performance Stock Units

Direct

M · Option Exercise

Converts to

Common Stock

7.50K shares

−7.50K

Strike price

Held after

0.00

Exercisable

—

2/27/2026

Restricted Stock Units

Direct

M · Option Exercise

Converts to

Common Stock

550.00 shares

−550.00

Strike price

Held after

1.65K

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

A · Award

Converts to

Common Stock

13.57K shares

+13.57K

Strike price

275.64

Held after

13.57K

Exercisable

—

2/27/2026

Restricted Stock Units

Direct

A · Award

Converts to

Common Stock

5.44K shares

+5.44K

Strike price

Held after

5.44K

Exercisable

—

2/27/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Performance Stock Units Direct	Common Stock7.50K shares	2/27/2026	M · Option Exercise	−7.50K		—	0.00
Restricted Stock Units Direct	Common Stock550.00 shares	2/27/2026	M · Option Exercise	−550.00		—	1.65K
Stock Option (Right to Buy) Direct	Common Stock13.57K shares	2/27/2026	A · Award	+13.57K	275.64	—	13.57K
Restricted Stock Units Direct	Common Stock5.44K shares	2/27/2026	A · Award	+5.44K		—	5.44K