PROPEL BIO MANAGEMENT, LLC

Filed: 2/14/2025ACC: 0001829126-25-000973

📋 What this filing means

PROPEL BIO MANAGEMENT, LLC filed this quarterly 13F‑HR report disclosing 21 equity positions with a total reported market value of $100.69M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.

Positions

$100.69M

Total AUM (reported)

20.89M

Total Shares

Allocation by class

COMM$100.69M100.0%

Portfolio Concentration

Top 3$46.23M45.9%

4–10$44.74M44.4%

11–25$9.73M9.7%

Top 3 weight

45.9%

Top 10 weight

90.3%

Voting Authority Distribution

Total shares with voting rights: 20.89M

Sole

Full voting authority

11.47M

% of voting shares54.9%

Shared

Joint voting authority

9.42M

% of voting shares45.1%

None

No voting authority

0.00

% of voting shares0.0%

Investment Discretion (by position count)

Sole0

Shared0

Other21

Dominant voting typeSole · 54.9% of voting shares

Institutional Holdings21

Rows:

PLAINS GP HOLDINGS LP-CL

DFND

COMM

Shares1.27M

TypeSH

Market value$23.39M

23.23%

Sole

0.00

Shared

1.27M

None

0.00

MADRIGAL PHARMACEUTICALS

DFND

COMM

Shares43.03K

TypeSH

Market value$13.28M

13.19%

Sole

19.74K

Shared

23.29K

None

0.00

AKERO THERAPEUTICS INC

DFND

COMM

Shares343.73K

TypeSH

Market value$9.56M

9.50%

Sole

115.28K

Shared

228.45K

None

0.00

ACHIEVE LIFE SCIENCES INC

DFND

COMM

Shares2.45M

TypeSH

Market value$8.63M

8.58%

Sole

2.24M

Shared

217.84K

None

0.00

APPLIED THERAPEUTICS INC

DFND

COMM

Shares9.62M

TypeSH

Market value$8.23M

8.18%

Sole

6.80M

Shared

2.82M

None

0.00

PHATHOM PHARMACEUTICALS I

DFND

COMM

Shares989.93K

TypeSH

Market value$8.04M

7.98%

Sole

407.99K

Shared

581.93K

None

0.00

TSCAN THERAPEUTICS INC

DFND

COMM

Shares2.09M

TypeSH

Market value$6.34M

6.30%

Sole

1.04M

Shared

1.05M

None

0.00

AVIDITY BIOSCIENCES INC

DFND

COMM

Shares178.50K

TypeSH

Market value$5.19M

5.16%

Sole

53.50K

Shared

125K

None

0.00

ARDELYX INC

DFND

COMM

Shares950.95K

TypeSH

Market value$4.82M

4.79%

Sole

261.58K

Shared

689.36K

None

0.00

ABEONA THERAPEUTICS INC

DFND

COMM

Shares624.02K

TypeSH

Market value$3.48M

3.45%

Sole

215.44K

Shared

408.58K

None

0.00

SYNDAX PHARMACEUTICALS IN

DFND

COMM

Shares183.26K

TypeSH

Market value$2.42M

2.41%

Sole

63.26K

Shared

120K

None

0.00

KYMERA THERAPEUTICS INC

DFND

COMM

Shares56.36K

TypeSH

Market value$2.27M

2.25%

Sole

25.84K

Shared

30.52K

None

0.00

ZEVRA THERAPEUTICS INC

DFND

COMM

Shares179.87K

TypeSH

Market value$1.50M

1.49%

Sole

59.87K

Shared

120K

None

0.00

KURA ONCOLOGY INC

DFND

COMM

Shares130K

TypeSH

Market value$1.13M

1.12%

Sole

50K

Shared

80K

None

0.00

ATHIRA PHARMA INC

DFND

COMM

Shares1.49M

TypeSH

Market value$875.8K

0.87%

Sole

0.00

Shared

1.49M

None

0.00

EIGER BIOPHARMACEUTICALS

DFND

COMM

Shares146.38K

TypeSH

Market value$765.0K

0.76%

Sole

56.38K

Shared

90K

None

0.00

JASPER THERAPEUTICS INC

DFND

COMM

Shares20K

TypeSH

Market value$427.6K

0.42%

Sole

0.00

Shared

20K

None

0.00

DELCATH SYSTEMS INC

DFND

COMM

Shares17K

TypeSH

Market value$204.7K

0.20%

Sole

0.00

Shared

17K

None

0.00

COMPASS PATHWAYS PLC

DFND

COMM

Shares25.21K

TypeSH

Market value$95.3K

0.09%

Sole

10.96K

Shared

14.25K

None

0.00

MAAT PHARMA SACA

DFND

COMM

Shares3.15K

TypeSH

Market value$25.1K

0.02%

Sole

0.00

Shared

3.15K

None

0.00

CHINOOK THERAPEUTICS

DFND

COMM

Shares79.36K

TypeSH

Market value$9.8K

<0.01%

Sole

54.36K

Shared

25K

None

0.00

Issuer	Class	Shares	Type	Value / Portfolio %	Voting — Sole	Shared
PLAINS GP HOLDINGS LP-CLDFND	COMM	1.27M	SH	$23.39M 23.23%	0.00	1.27M
MADRIGAL PHARMACEUTICALSDFND	COMM	43.03K	SH	$13.28M 13.19%	19.74K	23.29K
AKERO THERAPEUTICS INCDFND	COMM	343.73K	SH	$9.56M 9.50%	115.28K	228.45K
ACHIEVE LIFE SCIENCES INCDFND	COMM	2.45M	SH	$8.63M 8.58%	2.24M	217.84K
APPLIED THERAPEUTICS INCDFND	COMM	9.62M	SH	$8.23M 8.18%	6.80M	2.82M
PHATHOM PHARMACEUTICALS IDFND	COMM	989.93K	SH	$8.04M 7.98%	407.99K	581.93K
TSCAN THERAPEUTICS INCDFND	COMM	2.09M	SH	$6.34M 6.30%	1.04M	1.05M
AVIDITY BIOSCIENCES INCDFND	COMM	178.50K	SH	$5.19M 5.16%	53.50K	125K
ARDELYX INCDFND	COMM	950.95K	SH	$4.82M 4.79%	261.58K	689.36K
ABEONA THERAPEUTICS INCDFND	COMM	624.02K	SH	$3.48M 3.45%	215.44K	408.58K
SYNDAX PHARMACEUTICALS INDFND	COMM	183.26K	SH	$2.42M 2.41%	63.26K	120K
KYMERA THERAPEUTICS INCDFND	COMM	56.36K	SH	$2.27M 2.25%	25.84K	30.52K
ZEVRA THERAPEUTICS INCDFND	COMM	179.87K	SH	$1.50M 1.49%	59.87K	120K
KURA ONCOLOGY INCDFND	COMM	130K	SH	$1.13M 1.12%	50K	80K
ATHIRA PHARMA INCDFND	COMM	1.49M	SH	$875.8K 0.87%	0.00	1.49M
EIGER BIOPHARMACEUTICALSDFND	COMM	146.38K	SH	$765.0K 0.76%	56.38K	90K
JASPER THERAPEUTICS INCDFND	COMM	20K	SH	$427.6K 0.42%	0.00	20K
DELCATH SYSTEMS INCDFND	COMM	17K	SH	$204.7K 0.20%	0.00	17K
COMPASS PATHWAYS PLCDFND	COMM	25.21K	SH	$95.3K 0.09%	10.96K	14.25K
MAAT PHARMA SACADFND	COMM	3.15K	SH	$25.1K 0.02%	0.00	3.15K
CHINOOK THERAPEUTICSDFND	COMM	79.36K	SH	$9.8K <0.01%	54.36K	25K