PROPEL BIO MANAGEMENT, LLC

Filed: 5/15/2025ACC: 0000898432-25-000357

📋 What this filing means

PROPEL BIO MANAGEMENT, LLC filed this quarterly 13F‑HR report disclosing 18 equity positions with a total reported market value of $86.07M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.

Positions

$86.07M

Total AUM (reported)

23.40M

Total Shares

Allocation by class

COMM$86.07M100.0%

Portfolio Concentration

Top 3$46.39M53.9%

4–10$32.56M37.8%

11–25$7.12M8.3%

Top 3 weight

53.9%

Top 10 weight

91.7%

Voting Authority Distribution

Total shares with voting rights: 23.40M

Sole

Full voting authority

11.90M

% of voting shares50.8%

Shared

Joint voting authority

11.50M

% of voting shares49.2%

None

No voting authority

0.00

% of voting shares0.0%

Investment Discretion (by position count)

Sole0

Shared0

Other18

Dominant voting typeSole · 50.8% of voting shares

Institutional Holdings18

Rows:

PLAINS GP HOLDINGS LP-CL

DFND

COMM

Shares1.27M

TypeSH

Market value$27.18M

31.57%

Sole

0.00

Shared

1.27M

None

0.00

MADRIGAL PHARMACEUTICALS

DFND

COMM

Shares30.03K

TypeSH

Market value$9.95M

11.56%

Sole

13.74K

Shared

16.29K

None

0.00

AKERO THERAPEUTICS INC

DFND

COMM

Shares228.88K

TypeSH

Market value$9.27M

10.76%

Sole

83.28K

Shared

145.61K

None

0.00

PHATHOM PHARMACEUTICALS I

DFND

COMM

Shares1.13M

TypeSH

Market value$7.12M

8.27%

Sole

452.99K

Shared

681.93K

None

0.00

ACHIEVE LIFE SCIENCES INC

DFND

COMM

Shares2.45M

TypeSH

Market value$6.55M

7.61%

Sole

2.24M

Shared

217.84K

None

0.00

APPLIED THERAPEUTICS INC

DFND

COMM

Shares11.29M

TypeSH

Market value$5.52M

6.41%

Sole

6.80M

Shared

4.49M

None

0.00

AVIDITY BIOSCIENCES INC

DFND

COMM

Shares178.50K

TypeSH

Market value$5.27M

6.12%

Sole

53.50K

Shared

125K

None

0.00

ABEONA THERAPEUTICS INC

DFND

COMM

Shares624.02K

TypeSH

Market value$2.97M

3.45%

Sole

215.44K

Shared

408.58K

None

0.00

TSCAN THERAPEUTICS INC

DFND

COMM

Shares2.09M

TypeSH

Market value$2.88M

3.35%

Sole

1.04M

Shared

1.05M

None

0.00

DELCATH SYSTEMS INC

DFND

COMM

Shares177.60K

TypeSH

Market value$2.26M

2.63%

Sole

60.60K

Shared

117K

None

0.00

SYNDAX PHARMACEUTICALS IN

DFND

COMM

Shares183.26K

TypeSH

Market value$2.25M

2.62%

Sole

63.26K

Shared

120K

None

0.00

ZEVRA THERAPEUTICS INC

DFND

COMM

Shares179.87K

TypeSH

Market value$1.35M

1.57%

Sole

59.87K

Shared

120K

None

0.00

MILESTONE PHARMACEUTICALS

DFND

COMM

Shares1.45M

TypeSH

Market value$1.16M

1.35%

Sole

601.56K

Shared

850K

None

0.00

MAAT PHARMA SACA

DFND

COMM

Shares166.42K

TypeSH

Market value$1.04M

1.21%

Sole

0.00

Shared

166.42K

None

0.00

COMPASS THERAPEUTICS INC

DFND

COMM

Shares228.32K

TypeSH

Market value$433.8K

0.50%

Sole

108.32K

Shared

120K

None

0.00

ATHIRA PHARMA INC

DFND

COMM

Shares1.49M

TypeSH

Market value$425.3K

0.49%

Sole

0.00

Shared

1.49M

None

0.00

EIGER BIOPHARMACEUTICALS

DFND

COMM

Shares146.38K

TypeSH

Market value$423.0K

0.49%

Sole

56.38K

Shared

90K

None

0.00

CHINOOK THERAPEUTICS

DFND

COMM

Shares79.36K

TypeSH

Market value$38.5K

0.04%

Sole

54.36K

Shared

25K

None

0.00

Issuer	Class	Shares	Type	Value / Portfolio %	Voting — Sole	Shared
PLAINS GP HOLDINGS LP-CLDFND	COMM	1.27M	SH	$27.18M 31.57%	0.00	1.27M
MADRIGAL PHARMACEUTICALSDFND	COMM	30.03K	SH	$9.95M 11.56%	13.74K	16.29K
AKERO THERAPEUTICS INCDFND	COMM	228.88K	SH	$9.27M 10.76%	83.28K	145.61K
PHATHOM PHARMACEUTICALS IDFND	COMM	1.13M	SH	$7.12M 8.27%	452.99K	681.93K
ACHIEVE LIFE SCIENCES INCDFND	COMM	2.45M	SH	$6.55M 7.61%	2.24M	217.84K
APPLIED THERAPEUTICS INCDFND	COMM	11.29M	SH	$5.52M 6.41%	6.80M	4.49M
AVIDITY BIOSCIENCES INCDFND	COMM	178.50K	SH	$5.27M 6.12%	53.50K	125K
ABEONA THERAPEUTICS INCDFND	COMM	624.02K	SH	$2.97M 3.45%	215.44K	408.58K
TSCAN THERAPEUTICS INCDFND	COMM	2.09M	SH	$2.88M 3.35%	1.04M	1.05M
DELCATH SYSTEMS INCDFND	COMM	177.60K	SH	$2.26M 2.63%	60.60K	117K
SYNDAX PHARMACEUTICALS INDFND	COMM	183.26K	SH	$2.25M 2.62%	63.26K	120K
ZEVRA THERAPEUTICS INCDFND	COMM	179.87K	SH	$1.35M 1.57%	59.87K	120K
MILESTONE PHARMACEUTICALSDFND	COMM	1.45M	SH	$1.16M 1.35%	601.56K	850K
MAAT PHARMA SACADFND	COMM	166.42K	SH	$1.04M 1.21%	0.00	166.42K
COMPASS THERAPEUTICS INCDFND	COMM	228.32K	SH	$433.8K 0.50%	108.32K	120K
ATHIRA PHARMA INCDFND	COMM	1.49M	SH	$425.3K 0.49%	0.00	1.49M
EIGER BIOPHARMACEUTICALSDFND	COMM	146.38K	SH	$423.0K 0.49%	56.38K	90K
CHINOOK THERAPEUTICSDFND	COMM	79.36K	SH	$38.5K 0.04%	54.36K	25K