PERCEPTIVE ADVISORS LLC exercised options at LEONABIO, INC.

Option exercise — a mechanical event triggered by vesting or expiry. Not a discretionary conviction trade.

M · 1 exercise

PERCEPTIVE ADVISORS LLC

Filed: 10/26/2026ACC: 0001193125-26-431896

InsiderPERCEPTIVE ADVISORS LLCCIK 1224962

→

IssuerLEONABIO, INC.CIK 1620463

10% Owner

Since Sep 2020

0.00

Net shares

Net seller

$776.65

Total acquired

Open market trades

0B · 0S

Total transactions

776.65K acquired · 776.65K disposed

Non-Derivative Transactions1

Common Stock

Indirect

M · Option Exercise

+776.65K

Price / share

$0.00

Trade value

$776.65

% of position

New position

10/26/2026

0.00→776.65K

Total

Net shares

+776.65K

Net value

$776.65

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Indirect	10/26/2026	M · Option Exercise	+776.65K	$0.00	$776.65	New position	0.00	776.65K
Total			+776.65K		$776.65

Derivative Transactions1

Pre-Funded Warrant (right to buy)

Indirect

M · Option Exercise

Converts to

Common Stock

776.65K shares

−776.65K

Strike price

0.001

Held after

0.00

Exercisable

—

10/26/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Pre-Funded Warrant (right to buy) Indirect	Common Stock776.65K shares	10/26/2026	M · Option Exercise	−776.65K	0.001	—	0.00

Non-Derivative Holdings (Post-Transaction)2

Common Stock

Indirect

Shares owned329.76K

Common Stock

Indirect

Shares owned1.53M

Total

1.86M indirect1.86M

Security Title	Shares Owned	Ownership Type
Common Stock	329.76K	Indirect
Common Stock	1.53M	Indirect
Total	1.86M	1.86M indirect

Derivative Holdings (Post-Transaction)3

Pre-Funded Warrant (right to buy)

Indirect

Underlying security

Common Stock

Underlying shares

2.35M

Shares owned

2.35M

Exercise price

0.001

Expiration

—

Exercise window

—

Pre-Funded Warrant (right to buy)

Indirect

Underlying security

Common Stock

Underlying shares

457.64K

Shares owned

457.64K

Exercise price

0.001

Expiration

—

Exercise window

—

Pre-Funded Warrant (right to warrant)

Indirect

Underlying security

Common Stock

Underlying shares

1.37M

Shares owned

1.37M

Exercise price

0.001

Expiration

—

Exercise window

—

Total

Underlying

4.18M

Owned

4.18M

Security	Underlying	Exercise Price	Exercise Window	Expiration	Underlying Shares	Shares Owned
Pre-Funded Warrant (right to buy) Indirect	Common Stock	0.001	—	—	2.35M	2.35M
Pre-Funded Warrant (right to buy) Indirect	Common Stock	0.001	—	—	457.64K	457.64K
Pre-Funded Warrant (right to warrant) Indirect	Common Stock	0.001	—	—	1.37M	1.37M
Total					4.18M	4.18M