Filed: 2/17/2026ACC: 0001855655-26-000003
📋 What this filing means
PARADIGM BIOCAPITAL ADVISORS LP filed this quarterly 13F‑HR report disclosing 30 equity positions with a total reported market value of $3.92B. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
30
Positions
$3.92B
Total AUM (reported)
103.38M
Total Shares
Allocation by class
COM$2.58B65.8%
SPONSORED ADS$407.98M10.4%
COMMON STOCK$373.21M9.5%
COM NEW$357.12M9.1%
STATE STREET SPD$182.90M4.7%
ADS$18.60M0.5%
Portfolio Concentration
Top 3$1.43B36.6%
4–10$1.34B34.3%
11–25$1.05B26.8%
Rest$89.67M2.3%
Top 3 weight
36.6%
Top 10 weight
70.9%
Voting Authority Distribution
Total shares with voting rights: 103.38M
Sole
Full voting authority
103.38M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole30
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings30
Rows:
NUVALENT INC
SOLEShares5.27M
TypeSH
Market value$530.05M
13.53%
Sole
5.27M
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares6.64M
TypeSH
Market value$529.23M
13.51%
Sole
6.64M
Shared
0.00
None
0.00
ARCELLX INC
SOLEShares5.72M
TypeSH
Market value$373.21M
9.53%
Sole
5.72M
Shared
0.00
None
0.00
GENMAB A/S
SOLEShares7.04M
TypeSH
Market value$216.83M
5.53%
Sole
7.04M
Shared
0.00
None
0.00
TARSUS PHARMACEUTICALS INC
SOLEShares2.56M
TypeSH
Market value$209.79M
5.35%
Sole
2.56M
Shared
0.00
None
0.00
ABIVAX SA
SOLEShares1.42M
TypeSH
Market value$191.15M
4.88%
Sole
1.42M
Shared
0.00
None
0.00
OLEMA PHARMACEUTICALS INC
SOLEShares7.54M
TypeSH
Market value$188.60M
4.81%
Sole
7.54M
Shared
0.00
None
0.00
VAXCYTE INC
SOLEShares4.07M
TypeSH
Market value$187.70M
4.79%
Sole
4.07M
Shared
0.00
None
0.00
SPDR SERIES TRUST
SOLEShares1.50M
TypeSH
Market value$182.90M
4.67%
Sole
1.50M
Shared
0.00
None
0.00
CIDARA THERAPEUTICS INC
SOLEShares759.57K
TypeSH
Market value$167.78M
4.28%
Sole
759.57K
Shared
0.00
None
0.00
EDGEWISE THERAPEUTICS INC
SOLEShares6.54M
TypeSH
Market value$162.32M
4.14%
Sole
6.54M
Shared
0.00
None
0.00
SCHOLAR ROCK HLDG CORP
SOLEShares3.06M
TypeSH
Market value$134.89M
3.44%
Sole
3.06M
Shared
0.00
None
0.00
UROGEN PHARMA LTD
SOLEShares4.47M
TypeSH
Market value$104.77M
2.67%
Sole
4.47M
Shared
0.00
None
0.00
CRINETICS PHARMACEUTICALS IN
SOLEShares2.21M
TypeSH
Market value$102.91M
2.63%
Sole
2.21M
Shared
0.00
None
0.00
APOGEE THERAPEUTICS INC
SOLEShares1.12M
TypeSH
Market value$84.78M
2.16%
Sole
1.12M
Shared
0.00
None
0.00
EYEPOINT INC
SOLEShares3.69M
TypeSH
Market value$67.44M
1.72%
Sole
3.69M
Shared
0.00
None
0.00
ERASCA INC
SOLEShares14.16M
TypeSH
Market value$52.67M
1.34%
Sole
14.16M
Shared
0.00
None
0.00
BRIDGEBIO PHARMA INC
SOLEShares684.28K
TypeSH
Market value$52.34M
1.34%
Sole
684.28K
Shared
0.00
None
0.00
ORUKA THERAPEUTICS INC
SOLEShares1.71M
TypeSH
Market value$51.84M
1.32%
Sole
1.71M
Shared
0.00
None
0.00
SPYRE THERAPEUTICS INC
SOLEShares1.47M
TypeSH
Market value$48.07M
1.23%
Sole
1.47M
Shared
0.00
None
0.00
LEXEO THERAPEUTICS INC
SOLEShares4.76M
TypeSH
Market value$47.30M
1.21%
Sole
4.76M
Shared
0.00
None
0.00
VIRIDIAN THERAPEUTICS INC
SOLEShares1.44M
TypeSH
Market value$44.91M
1.15%
Sole
1.44M
Shared
0.00
None
0.00
OCULAR THERAPEUTIX INC
SOLEShares2.94M
TypeSH
Market value$35.63M
0.91%
Sole
2.94M
Shared
0.00
None
0.00
TERNS PHARMACEUTICALS INC
SOLEShares810.29K
TypeSH
Market value$32.74M
0.84%
Sole
810.29K
Shared
0.00
None
0.00
BRIDGEBIO ONCOLOGY THERAPEUT
SOLEShares2.26M
TypeSH
Market value$28.32M
0.72%
Sole
2.26M
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
NUVALENT INCSOLE | COM | 5.27M | SH | $530.05M 13.53% | 5.27M | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 6.64M | SH | $529.23M 13.51% | 6.64M | 0.00 | 0.00 |
ARCELLX INCSOLE | COMMON STOCK | 5.72M | SH | $373.21M 9.53% | 5.72M | 0.00 | 0.00 |
GENMAB A/SSOLE | SPONSORED ADS | 7.04M | SH | $216.83M 5.53% | 7.04M | 0.00 | 0.00 |
TARSUS PHARMACEUTICALS INCSOLE | COM | 2.56M | SH | $209.79M 5.35% | 2.56M | 0.00 | 0.00 |
ABIVAX SASOLE | SPONSORED ADS | 1.42M | SH | $191.15M 4.88% | 1.42M | 0.00 | 0.00 |
OLEMA PHARMACEUTICALS INCSOLE | COM | 7.54M | SH | $188.60M 4.81% | 7.54M | 0.00 | 0.00 |
VAXCYTE INCSOLE | COM | 4.07M | SH | $187.70M 4.79% | 4.07M | 0.00 | 0.00 |
SPDR SERIES TRUSTSOLE | STATE STREET SPD | 1.50M | SH | $182.90M 4.67% | 1.50M | 0.00 | 0.00 |
CIDARA THERAPEUTICS INCSOLE | COM NEW | 759.57K | SH | $167.78M 4.28% | 759.57K | 0.00 | 0.00 |
EDGEWISE THERAPEUTICS INCSOLE | COM | 6.54M | SH | $162.32M 4.14% | 6.54M | 0.00 | 0.00 |
SCHOLAR ROCK HLDG CORPSOLE | COM | 3.06M | SH | $134.89M 3.44% | 3.06M | 0.00 | 0.00 |
UROGEN PHARMA LTDSOLE | COM | 4.47M | SH | $104.77M 2.67% | 4.47M | 0.00 | 0.00 |
CRINETICS PHARMACEUTICALS INSOLE | COM | 2.21M | SH | $102.91M 2.63% | 2.21M | 0.00 | 0.00 |
APOGEE THERAPEUTICS INCSOLE | COM | 1.12M | SH | $84.78M 2.16% | 1.12M | 0.00 | 0.00 |
EYEPOINT INCSOLE | COM NEW | 3.69M | SH | $67.44M 1.72% | 3.69M | 0.00 | 0.00 |
ERASCA INCSOLE | COM | 14.16M | SH | $52.67M 1.34% | 14.16M | 0.00 | 0.00 |
BRIDGEBIO PHARMA INCSOLE | COM | 684.28K | SH | $52.34M 1.34% | 684.28K | 0.00 | 0.00 |
ORUKA THERAPEUTICS INCSOLE | COM | 1.71M | SH | $51.84M 1.32% | 1.71M | 0.00 | 0.00 |
SPYRE THERAPEUTICS INCSOLE | COM NEW | 1.47M | SH | $48.07M 1.23% | 1.47M | 0.00 | 0.00 |
LEXEO THERAPEUTICS INCSOLE | COM | 4.76M | SH | $47.30M 1.21% | 4.76M | 0.00 | 0.00 |
VIRIDIAN THERAPEUTICS INCSOLE | COM | 1.44M | SH | $44.91M 1.15% | 1.44M | 0.00 | 0.00 |
OCULAR THERAPEUTIX INCSOLE | COM | 2.94M | SH | $35.63M 0.91% | 2.94M | 0.00 | 0.00 |
TERNS PHARMACEUTICALS INCSOLE | COM | 810.29K | SH | $32.74M 0.84% | 810.29K | 0.00 | 0.00 |
BRIDGEBIO ONCOLOGY THERAPEUTSOLE | COM NEW | 2.26M | SH | $28.32M 0.72% | 2.26M | 0.00 | 0.00 |
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