Filed: 2/14/2025ACC: 0001855655-25-000004
📋 What this filing means
PARADIGM BIOCAPITAL ADVISORS LP filed this quarterly 13F‑HR report disclosing 28 equity positions with a total reported market value of $2.87B. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
28
Positions
$2.87B
Total AUM (reported)
80.86M
Total Shares
Allocation by class
COM$1.90B66.0%
SPONSORED ADR$409.79M14.3%
COMMON STOCK$335.26M11.7%
CLASS A ORD$95.97M3.3%
CL A$60.79M2.1%
SHS$38.50M1.3%
COM NEW$35.55M1.2%
Portfolio Concentration
Top 3$1.05B36.6%
4–10$1.06B37.0%
11–25$717.71M25.0%
Rest$42.26M1.5%
Top 3 weight
36.6%
Top 10 weight
73.6%
Voting Authority Distribution
Total shares with voting rights: 80.86M
Sole
Full voting authority
80.86M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole28
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings28
Rows:
NUVALENT INC
SOLEShares5.36M
TypeSH
Market value$419.85M
14.61%
Sole
5.36M
Shared
0.00
None
0.00
ARCELLX INC
SOLEShares4.37M
TypeSH
Market value$335.26M
11.66%
Sole
4.37M
Shared
0.00
None
0.00
ARGENX SE
SOLEShares481.31K
TypeSH
Market value$296.00M
10.30%
Sole
481.31K
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares6.55M
TypeSH
Market value$286.63M
9.97%
Sole
6.55M
Shared
0.00
None
0.00
JANUX THERAPEUTICS INC
SOLEShares3.52M
TypeSH
Market value$188.25M
6.55%
Sole
3.52M
Shared
0.00
None
0.00
TARSUS PHARMACEUTICALS INC
SOLEShares2.53M
TypeSH
Market value$140.19M
4.88%
Sole
2.53M
Shared
0.00
None
0.00
EDGEWISE THERAPEUTICS INC
SOLEShares4.49M
TypeSH
Market value$119.99M
4.17%
Sole
4.49M
Shared
0.00
None
0.00
VAXCYTE INC
SOLEShares1.42M
TypeSH
Market value$116.47M
4.05%
Sole
1.42M
Shared
0.00
None
0.00
BEIGENE LTD
SOLEShares616.02K
TypeSH
Market value$113.79M
3.96%
Sole
616.02K
Shared
0.00
None
0.00
CRINETICS PHARMACEUTICALS IN
SOLEShares1.91M
TypeSH
Market value$97.70M
3.40%
Sole
1.91M
Shared
0.00
None
0.00
MOONLAKE IMMUNOTHERAPEUTICS
SOLEShares1.77M
TypeSH
Market value$95.97M
3.34%
Sole
1.77M
Shared
0.00
None
0.00
DISC MEDICINE INC
SOLEShares1.50M
TypeSH
Market value$94.96M
3.30%
Sole
1.50M
Shared
0.00
None
0.00
MERUS N V
SOLEShares1.69M
TypeSH
Market value$71.06M
2.47%
Sole
1.69M
Shared
0.00
None
0.00
VERA THERAPEUTICS INC
SOLEShares1.44M
TypeSH
Market value$60.79M
2.11%
Sole
1.44M
Shared
0.00
None
0.00
APOGEE THERAPEUTICS INC
SOLEShares1.28M
TypeSH
Market value$58.15M
2.02%
Sole
1.28M
Shared
0.00
None
0.00
OLEMA PHARMACEUTICALS INC
SOLEShares7.30M
TypeSH
Market value$42.59M
1.48%
Sole
7.30M
Shared
0.00
None
0.00
PLIANT THERAPEUTICS INC
SOLEShares3.20M
TypeSH
Market value$42.11M
1.46%
Sole
3.20M
Shared
0.00
None
0.00
IMMATICS N.V
SOLEShares5.41M
TypeSH
Market value$38.50M
1.34%
Sole
5.41M
Shared
0.00
None
0.00
COGENT BIOSCIENCES INC
SOLEShares4.92M
TypeSH
Market value$38.36M
1.33%
Sole
4.92M
Shared
0.00
None
0.00
SPYRE THERAPEUTICS INC
SOLEShares1.53M
TypeSH
Market value$35.55M
1.24%
Sole
1.53M
Shared
0.00
None
0.00
VIRIDIAN THERAPEUTICS INC
SOLEShares1.82M
TypeSH
Market value$34.89M
1.21%
Sole
1.82M
Shared
0.00
None
0.00
Y-MABS THERAPEUTICS INC
SOLEShares4.24M
TypeSH
Market value$33.17M
1.15%
Sole
4.24M
Shared
0.00
None
0.00
ERASCA INC
SOLEShares10.75M
TypeSH
Market value$26.99M
0.94%
Sole
10.75M
Shared
0.00
None
0.00
TECTONIC THERAPEUTIC INC
SOLEShares485.11K
TypeSH
Market value$22.40M
0.78%
Sole
485.11K
Shared
0.00
None
0.00
LENZ THERAPEUTICS INC
SOLEShares770.46K
TypeSH
Market value$22.24M
0.77%
Sole
770.46K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
NUVALENT INCSOLE | COM | 5.36M | SH | $419.85M 14.61% | 5.36M | 0.00 | 0.00 |
ARCELLX INCSOLE | COMMON STOCK | 4.37M | SH | $335.26M 11.66% | 4.37M | 0.00 | 0.00 |
ARGENX SESOLE | SPONSORED ADR | 481.31K | SH | $296.00M 10.30% | 481.31K | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 6.55M | SH | $286.63M 9.97% | 6.55M | 0.00 | 0.00 |
JANUX THERAPEUTICS INCSOLE | COM | 3.52M | SH | $188.25M 6.55% | 3.52M | 0.00 | 0.00 |
TARSUS PHARMACEUTICALS INCSOLE | COM | 2.53M | SH | $140.19M 4.88% | 2.53M | 0.00 | 0.00 |
EDGEWISE THERAPEUTICS INCSOLE | COM | 4.49M | SH | $119.99M 4.17% | 4.49M | 0.00 | 0.00 |
VAXCYTE INCSOLE | COM | 1.42M | SH | $116.47M 4.05% | 1.42M | 0.00 | 0.00 |
BEIGENE LTDSOLE | SPONSORED ADR | 616.02K | SH | $113.79M 3.96% | 616.02K | 0.00 | 0.00 |
CRINETICS PHARMACEUTICALS INSOLE | COM | 1.91M | SH | $97.70M 3.40% | 1.91M | 0.00 | 0.00 |
MOONLAKE IMMUNOTHERAPEUTICSSOLE | CLASS A ORD | 1.77M | SH | $95.97M 3.34% | 1.77M | 0.00 | 0.00 |
DISC MEDICINE INCSOLE | COM | 1.50M | SH | $94.96M 3.30% | 1.50M | 0.00 | 0.00 |
MERUS N VSOLE | COM | 1.69M | SH | $71.06M 2.47% | 1.69M | 0.00 | 0.00 |
VERA THERAPEUTICS INCSOLE | CL A | 1.44M | SH | $60.79M 2.11% | 1.44M | 0.00 | 0.00 |
APOGEE THERAPEUTICS INCSOLE | COM | 1.28M | SH | $58.15M 2.02% | 1.28M | 0.00 | 0.00 |
OLEMA PHARMACEUTICALS INCSOLE | COM | 7.30M | SH | $42.59M 1.48% | 7.30M | 0.00 | 0.00 |
PLIANT THERAPEUTICS INCSOLE | COM | 3.20M | SH | $42.11M 1.46% | 3.20M | 0.00 | 0.00 |
IMMATICS N.VSOLE | SHS | 5.41M | SH | $38.50M 1.34% | 5.41M | 0.00 | 0.00 |
COGENT BIOSCIENCES INCSOLE | COM | 4.92M | SH | $38.36M 1.33% | 4.92M | 0.00 | 0.00 |
SPYRE THERAPEUTICS INCSOLE | COM NEW | 1.53M | SH | $35.55M 1.24% | 1.53M | 0.00 | 0.00 |
VIRIDIAN THERAPEUTICS INCSOLE | COM | 1.82M | SH | $34.89M 1.21% | 1.82M | 0.00 | 0.00 |
Y-MABS THERAPEUTICS INCSOLE | COM | 4.24M | SH | $33.17M 1.15% | 4.24M | 0.00 | 0.00 |
ERASCA INCSOLE | COM | 10.75M | SH | $26.99M 0.94% | 10.75M | 0.00 | 0.00 |
TECTONIC THERAPEUTIC INCSOLE | COM | 485.11K | SH | $22.40M 0.78% | 485.11K | 0.00 | 0.00 |
LENZ THERAPEUTICS INCSOLE | COM | 770.46K | SH | $22.24M 0.77% | 770.46K | 0.00 | 0.00 |
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