OYLER JOHN (Chief Executive Officer) sold 109.71K shares of BEONE MEDICINES LTD. on the open market

Open‑market sale worth $34.59M. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 14 sales

OYLER JOHN

Filed: 7/22/2026ACC: 0001042047-26-000017

InsiderOYLER JOHNCIK 1042047

→

IssuerBEONE MEDICINES LTD.CIK 1651308

DirectorOfficer10% Owner· Chief Executive Officer

Since Jul 2018

-517.59K

Net shares

Net seller

$34.59M

Total sold

Open market trades

0B · 14S

Total transactions

33.99K acquired · 551.58K disposed

Non-Derivative Transactions15

American Depositary Shares

Direct

S · Sale

−5.15K

Price / share

$310.08

Trade value

$1.60M

% of position

35.9%

7/20/2026

14.33K→9.18K

American Depositary Shares

Direct

S · Sale

−6.27K

Price / share

$310.75

Trade value

$1.95M

% of position

68.3%

7/20/2026

9.18K→2.91K

American Depositary Shares

Direct

S · Sale

−2.91K

Price / share

$311.80

Trade value

$906.39K

% of position

New position

7/20/2026

2.91K→0.00

American Depositary Shares

Direct

M · Option Exercise

+33.99K

Price / share

$119.96

Trade value

$4.08M

% of position

New position

7/20/2026

0.00→33.99K

American Depositary Shares

Direct

S · Sale

−15.50K

Price / share

$312.29

Trade value

$4.84M

% of position

45.6%

7/20/2026

33.99K→18.49K

American Depositary Shares

Direct

S · Sale

−14.33K

Price / share

$312.96

Trade value

$4.48M

% of position

77.5%

7/20/2026

18.49K→4.17K

American Depositary Shares

Direct

S · Sale

−1.85K

Price / share

$313.91

Trade value

$580.73K

% of position

44.4%

7/20/2026

4.17K→2.31K

American Depositary Shares

Direct

S · Sale

−1.51K

Price / share

$315.26

Trade value

$476.68K

% of position

65.3%

7/20/2026

2.31K→803.00

American Depositary Shares

Direct

S · Sale

−523.00

Price / share

$316.14

Trade value

$165.34K

% of position

65.1%

7/20/2026

803.00→280.00

American Depositary Shares

Direct

S · Sale

−280.00

Price / share

$318.30

Trade value

$89.12K

% of position

New position

7/20/2026

280.00→0.00

American Depositary Shares

Direct

S · Sale

−15.38K

Price / share

$316.26

Trade value

$4.86M

% of position

25.0%

7/21/2026

61.40K→46.02K

American Depositary Shares

Direct

S · Sale

−20.03K

Price / share

$316.91

Trade value

$6.35M

% of position

43.5%

7/21/2026

46.02K→25.99K

American Depositary Shares

Direct

S · Sale

−7.84K

Price / share

$318.41

Trade value

$2.50M

% of position

30.2%

7/21/2026

25.99K→18.15K

American Depositary Shares

Direct

S · Sale

−15.81K

Price / share

$319.29

Trade value

$5.05M

% of position

87.1%

7/21/2026

18.15K→2.34K

American Depositary Shares

Direct

S · Sale

−2.34K

Price / share

$320.06

Trade value

$748.94K

% of position

New position

7/21/2026

2.34K→0.00

Total

Net shares

−75.72K

Net value

-$30.51M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
American Depositary Shares Direct	7/20/2026	S · Sale	−5.15K	$310.08	$1.60M	35.9%	14.33K	9.18K
American Depositary Shares Direct	7/20/2026	S · Sale	−6.27K	$310.75	$1.95M	68.3%	9.18K	2.91K
American Depositary Shares Direct	7/20/2026	S · Sale	−2.91K	$311.80	$906.39K	New position	2.91K	0.00
American Depositary Shares Direct	7/20/2026	M · Option Exercise	+33.99K	$119.96	$4.08M	New position	0.00	33.99K
American Depositary Shares Direct	7/20/2026	S · Sale	−15.50K	$312.29	$4.84M	45.6%	33.99K	18.49K
American Depositary Shares Direct	7/20/2026	S · Sale	−14.33K	$312.96	$4.48M	77.5%	18.49K	4.17K
American Depositary Shares Direct	7/20/2026	S · Sale	−1.85K	$313.91	$580.73K	44.4%	4.17K	2.31K
American Depositary Shares Direct	7/20/2026	S · Sale	−1.51K	$315.26	$476.68K	65.3%	2.31K	803.00
American Depositary Shares Direct	7/20/2026	S · Sale	−523.00	$316.14	$165.34K	65.1%	803.00	280.00
American Depositary Shares Direct	7/20/2026	S · Sale	−280.00	$318.30	$89.12K	New position	280.00	0.00
American Depositary Shares Direct	7/21/2026	S · Sale	−15.38K	$316.26	$4.86M	25.0%	61.40K	46.02K
American Depositary Shares Direct	7/21/2026	S · Sale	−20.03K	$316.91	$6.35M	43.5%	46.02K	25.99K
American Depositary Shares Direct	7/21/2026	S · Sale	−7.84K	$318.41	$2.50M	30.2%	25.99K	18.15K
American Depositary Shares Direct	7/21/2026	S · Sale	−15.81K	$319.29	$5.05M	87.1%	18.15K	2.34K
American Depositary Shares Direct	7/21/2026	S · Sale	−2.34K	$320.06	$748.94K	New position	2.34K	0.00
Total			−75.72K		-$30.51M

Derivative Transactions1

Share Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

441.87K shares

−441.87K

Strike price

9.23

Held after

0.00

Exercisable

—

7/20/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Share Option (Right to Buy) Direct	Ordinary Shares441.87K shares	7/20/2026	M · Option Exercise	−441.87K	9.23	—	0.00

Non-Derivative Holdings (Post-Transaction)6

Ordinary Shares

Indirect

Shares owned102.19K

Ordinary Shares

Direct

Shares owned4.46M

Ordinary Shares

Indirect

Shares owned28.20M

Ordinary Shares

Indirect

Shares owned481.53K

Ordinary Shares

Indirect

Shares owned7.70M

Ordinary Shares

Indirect

Shares owned9.54M

Total

4.46M direct·46.03M indirect50.49M

Security Title	Shares Owned	Ownership Type
Ordinary Shares	102.19K	Indirect
Ordinary Shares	4.46M	Direct
Ordinary Shares	28.20M	Indirect
Ordinary Shares	481.53K	Indirect
Ordinary Shares	7.70M	Indirect
Ordinary Shares	9.54M	Indirect
Total	50.49M	4.46M direct·46.03M indirect

Derivative Holdings (Post-Transaction)0

No derivative holdings reported