OYLER JOHN (Chief Executive Officer) sold 283.15K shares of BEONE MEDICINES LTD. on the open market

Open‑market sale worth $89.35M. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 17 sales

OYLER JOHN

Filed: 7/17/2026ACC: 0001042047-26-000014

InsiderOYLER JOHNCIK 1042047

→

IssuerBEONE MEDICINES LTD.CIK 1651308

DirectorOfficer10% Owner· Chief Executive Officer

Since Jul 2018

-3.68M

Net shares

Net seller

$89.35M

Total sold

Open market trades

0B · 17S

Total transactions

283.15K acquired · 3.96M disposed

Non-Derivative Transactions22

American Depositary Shares

Direct

M · Option Exercise

+35.60K

Price / share

$100.04

Trade value

$3.56M

% of position

New position

7/15/2026

0.00→35.60K

American Depositary Shares

Direct

M · Option Exercise

+76.68K

Price / share

$169.58

Trade value

$13M

% of position

215.4%

7/15/2026

35.60K→112.28K

American Depositary Shares

Direct

M · Option Exercise

+4.28K

Price / share

$160.40

Trade value

$685.71K

% of position

3.8%

7/15/2026

112.28K→116.56K

American Depositary Shares

Direct

S · Sale

−6.07K

Price / share

$310.02

Trade value

$1.88M

% of position

5.2%

7/15/2026

116.56K→110.49K

American Depositary Shares

Direct

S · Sale

−41.34K

Price / share

$310.92

Trade value

$12.85M

% of position

37.4%

7/15/2026

110.49K→69.15K

American Depositary Shares

Direct

S · Sale

−12.86K

Price / share

$311.71

Trade value

$4.01M

% of position

18.6%

7/15/2026

69.15K→56.30K

American Depositary Shares

Direct

S · Sale

−48.66K

Price / share

$312.86

Trade value

$15.22M

% of position

86.4%

7/15/2026

56.30K→7.64K

American Depositary Shares

Direct

S · Sale

−7.64K

Price / share

$313.58

Trade value

$2.40M

% of position

New position

7/15/2026

7.64K→0.00

American Depositary Shares

Direct

M · Option Exercise

+96.50K

Price / share

$160.40

Trade value

$15.48M

% of position

New position

7/16/2026

0.00→96.50K

American Depositary Shares

Direct

M · Option Exercise

+70.10K

Price / share

$119.96

Trade value

$8.41M

% of position

72.6%

7/16/2026

96.50K→166.60K

American Depositary Shares

Direct

S · Sale

−233.00

Price / share

$311.98

Trade value

$72.69K

% of position

0.1%

7/16/2026

166.60K→166.36K

American Depositary Shares

Direct

S · Sale

−4.88K

Price / share

$314.08

Trade value

$1.53M

% of position

2.9%

7/16/2026

166.36K→161.48K

American Depositary Shares

Direct

S · Sale

−9.52K

Price / share

$314.73

Trade value

$2.99M

% of position

5.9%

7/16/2026

161.48K→151.97K

American Depositary Shares

Direct

S · Sale

−19.75K

Price / share

$316.00

Trade value

$6.24M

% of position

13.0%

7/16/2026

151.97K→132.22K

American Depositary Shares

Direct

S · Sale

−32.22K

Price / share

$316.82

Trade value

$10.21M

% of position

24.4%

7/16/2026

132.22K→99.99K

American Depositary Shares

Direct

S · Sale

−42.80K

Price / share

$317.79

Trade value

$13.60M

% of position

42.8%

7/16/2026

99.99K→57.19K

American Depositary Shares

Direct

S · Sale

−6.40K

Price / share

$318.55

Trade value

$2.04M

% of position

11.2%

7/16/2026

57.19K→50.79K

American Depositary Shares

Direct

S · Sale

−15.10K

Price / share

$319.99

Trade value

$4.83M

% of position

29.7%

7/16/2026

50.79K→35.69K

American Depositary Shares

Direct

S · Sale

−20.50K

Price / share

$321.00

Trade value

$6.58M

% of position

57.4%

7/16/2026

35.69K→15.19K

American Depositary Shares

Direct

S · Sale

−13.11K

Price / share

$321.61

Trade value

$4.22M

% of position

86.3%

7/16/2026

15.19K→2.08K

American Depositary Shares

Direct

S · Sale

−1.56K

Price / share

$322.71

Trade value

$503.42K

% of position

75.0%

7/16/2026

2.08K→520.00

American Depositary Shares

Direct

S · Sale

−520.00

Price / share

$323.59

Trade value

$168.26K

% of position

New position

7/16/2026

520.00→0.00

Total

Net shares

+0.00

Net value

-$48.21M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
American Depositary Shares Direct	7/15/2026	M · Option Exercise	+35.60K	$100.04	$3.56M	New position	0.00	35.60K
American Depositary Shares Direct	7/15/2026	M · Option Exercise	+76.68K	$169.58	$13M	215.4%	35.60K	112.28K
American Depositary Shares Direct	7/15/2026	M · Option Exercise	+4.28K	$160.40	$685.71K	3.8%	112.28K	116.56K
American Depositary Shares Direct	7/15/2026	S · Sale	−6.07K	$310.02	$1.88M	5.2%	116.56K	110.49K
American Depositary Shares Direct	7/15/2026	S · Sale	−41.34K	$310.92	$12.85M	37.4%	110.49K	69.15K
American Depositary Shares Direct	7/15/2026	S · Sale	−12.86K	$311.71	$4.01M	18.6%	69.15K	56.30K
American Depositary Shares Direct	7/15/2026	S · Sale	−48.66K	$312.86	$15.22M	86.4%	56.30K	7.64K
American Depositary Shares Direct	7/15/2026	S · Sale	−7.64K	$313.58	$2.40M	New position	7.64K	0.00
American Depositary Shares Direct	7/16/2026	M · Option Exercise	+96.50K	$160.40	$15.48M	New position	0.00	96.50K
American Depositary Shares Direct	7/16/2026	M · Option Exercise	+70.10K	$119.96	$8.41M	72.6%	96.50K	166.60K
American Depositary Shares Direct	7/16/2026	S · Sale	−233.00	$311.98	$72.69K	0.1%	166.60K	166.36K
American Depositary Shares Direct	7/16/2026	S · Sale	−4.88K	$314.08	$1.53M	2.9%	166.36K	161.48K
American Depositary Shares Direct	7/16/2026	S · Sale	−9.52K	$314.73	$2.99M	5.9%	161.48K	151.97K
American Depositary Shares Direct	7/16/2026	S · Sale	−19.75K	$316.00	$6.24M	13.0%	151.97K	132.22K
American Depositary Shares Direct	7/16/2026	S · Sale	−32.22K	$316.82	$10.21M	24.4%	132.22K	99.99K
American Depositary Shares Direct	7/16/2026	S · Sale	−42.80K	$317.79	$13.60M	42.8%	99.99K	57.19K
American Depositary Shares Direct	7/16/2026	S · Sale	−6.40K	$318.55	$2.04M	11.2%	57.19K	50.79K
American Depositary Shares Direct	7/16/2026	S · Sale	−15.10K	$319.99	$4.83M	29.7%	50.79K	35.69K
American Depositary Shares Direct	7/16/2026	S · Sale	−20.50K	$321.00	$6.58M	57.4%	35.69K	15.19K
American Depositary Shares Direct	7/16/2026	S · Sale	−13.11K	$321.61	$4.22M	86.3%	15.19K	2.08K
American Depositary Shares Direct	7/16/2026	S · Sale	−1.56K	$322.71	$503.42K	75.0%	2.08K	520.00
American Depositary Shares Direct	7/16/2026	S · Sale	−520.00	$323.59	$168.26K	New position	520.00	0.00
Total			+0.00		-$48.21M

Derivative Transactions5

Share Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

462.87K shares

−462.87K

Strike price

7.70

Held after

1.00

Exercisable

—

7/15/2026

Share Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

996.80K shares

−996.80K

Strike price

13.05

Held after

9.00

Exercisable

—

7/15/2026

Share Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

55.58K shares

−55.58K

Strike price

12.34

Held after

1.25M

Exercisable

—

7/15/2026

Share Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

1.25M shares

−1.25M

Strike price

12.34

Held after

0.00

Exercisable

—

7/16/2026

Share Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Ordinary Shares

911.25K shares

−911.25K

Strike price

9.23

Held after

1.28M

Exercisable

—

7/16/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Share Option (Right to Buy) Direct	Ordinary Shares462.87K shares	7/15/2026	M · Option Exercise	−462.87K	7.70	—	1.00
Share Option (Right to Buy) Direct	Ordinary Shares996.80K shares	7/15/2026	M · Option Exercise	−996.80K	13.05	—	9.00
Share Option (Right to Buy) Direct	Ordinary Shares55.58K shares	7/15/2026	M · Option Exercise	−55.58K	12.34	—	1.25M
Share Option (Right to Buy) Direct	Ordinary Shares1.25M shares	7/16/2026	M · Option Exercise	−1.25M	12.34	—	0.00
Share Option (Right to Buy) Direct	Ordinary Shares911.25K shares	7/16/2026	M · Option Exercise	−911.25K	9.23	—	1.28M

Non-Derivative Holdings (Post-Transaction)6

Ordinary Shares

Indirect

Shares owned9.54M

Ordinary Shares

Direct

Shares owned5.45M

Ordinary Shares

Indirect

Shares owned28.20M

Ordinary Shares

Indirect

Shares owned7.70M

Ordinary Shares

Indirect

Shares owned481.53K

Ordinary Shares

Indirect

Shares owned102.19K

Total

5.45M direct·46.03M indirect51.48M

Security Title	Shares Owned	Ownership Type
Ordinary Shares	9.54M	Indirect
Ordinary Shares	5.45M	Direct
Ordinary Shares	28.20M	Indirect
Ordinary Shares	7.70M	Indirect
Ordinary Shares	481.53K	Indirect
Ordinary Shares	102.19K	Indirect
Total	51.48M	5.45M direct·46.03M indirect

Derivative Holdings (Post-Transaction)0

No derivative holdings reported