Filed: 2/17/2026ACC: 0001493152-26-007085
📋 What this filing means
OPALEYE MANAGEMENT INC. filed this quarterly 13F‑HR report disclosing 54 equity positions with a total reported market value of $757.99M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
54
Positions
$757.99M
Total AUM (reported)
55.57M
Total Shares
Allocation by class
COM$579.42M76.4%
COM NEW$143.05M18.9%
SHS NEW$19.12M2.5%
SHS$13.71M1.8%
COM SHS$2.21M0.3%
ADS$479.9K0.1%
Portfolio Concentration
Top 3$324.69M42.8%
4–10$171.48M22.6%
11–25$173.41M22.9%
Rest$88.42M11.7%
Top 3 weight
42.8%
Top 10 weight
65.5%
Voting Authority Distribution
Total shares with voting rights: 55.57M
Sole
Full voting authority
55.57M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole54
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings54
Rows:
HARROW HEALTH INC
SOLEShares3.90M
TypeSH
Market value$191.34M
25.24%
Sole
3.90M
Shared
0.00
None
0.00
LIQUIDIA CORPORATION
SOLEShares2.44M
TypeSH
Market value$84.98M
11.21%
Sole
2.44M
Shared
0.00
None
0.00
ETON PHARMACEUTICALS INC
SOLEShares2.86M
TypeSH
Market value$48.36M
6.38%
Sole
2.86M
Shared
0.00
None
0.00
RHYTHM PHARMACEUTICALS INC
SOLEShares330K
TypeSH
Market value$35.32M
4.66%
Sole
330K
Shared
0.00
None
0.00
APOGEE THERAPEUTICS INC
SOLEShares388.26K
TypeSH
Market value$29.31M
3.87%
Sole
388.26K
Shared
0.00
None
0.00
SANUWAVE HEALTH INC
SOLEShares981.27K
TypeSH
Market value$29.28M
3.86%
Sole
981.27K
Shared
0.00
None
0.00
STOKE THERAPEUTICS INC
SOLEShares695K
TypeSH
Market value$22.06M
2.91%
Sole
695K
Shared
0.00
None
0.00
OCULAR THERAPEUTIX INC
SOLEShares1.59M
TypeSH
Market value$19.36M
2.55%
Sole
1.59M
Shared
0.00
None
0.00
SOL GEL TECHNOLOGIES
SOLEShares453.74K
TypeSH
Market value$19.12M
2.52%
Sole
453.74K
Shared
0.00
None
0.00
CG ONCOLOGY INC
SOLEShares410K
TypeSH
Market value$17.02M
2.25%
Sole
410K
Shared
0.00
None
0.00
TG THERAPEUTICS INC
SOLEShares535K
TypeSH
Market value$15.95M
2.10%
Sole
535K
Shared
0.00
None
0.00
DISC MEDICINE INC
SOLEShares200K
TypeSH
Market value$15.88M
2.10%
Sole
200K
Shared
0.00
None
0.00
REZOLUTE INC
SOLEShares6.29M
TypeSH
Market value$14.84M
1.96%
Sole
6.29M
Shared
0.00
None
0.00
CRESCENT BIOPHARMA INC
SOLEShares1.18M
TypeSH
Market value$13.97M
1.84%
Sole
1.18M
Shared
0.00
None
0.00
ALKERMES PLC
SOLEShares490K
TypeSH
Market value$13.71M
1.81%
Sole
490K
Shared
0.00
None
0.00
ALPHA COGNITION INC
SOLEShares2.07M
TypeSH
Market value$13.46M
1.78%
Sole
2.07M
Shared
0.00
None
0.00
ANNEXON INC
SOLEShares2.60M
TypeSH
Market value$13.05M
1.72%
Sole
2.60M
Shared
0.00
None
0.00
EDGEWISE THERAPEUTICS INC
SOLEShares500K
TypeSH
Market value$12.41M
1.64%
Sole
500K
Shared
0.00
None
0.00
CODEXIS INC
SOLEShares6.79M
TypeSH
Market value$11.07M
1.46%
Sole
6.79M
Shared
0.00
None
0.00
PROTAGONIST THERAPEUTICS INC
SOLEShares105K
TypeSH
Market value$9.17M
1.21%
Sole
105K
Shared
0.00
None
0.00
GOSSAMER BIO INC
SOLEShares2.72M
TypeSH
Market value$8.43M
1.11%
Sole
2.72M
Shared
0.00
None
0.00
MBX BIOSCIENCES INC
SOLEShares260K
TypeSH
Market value$8.20M
1.08%
Sole
260K
Shared
0.00
None
0.00
REVOLUTION MEDICINES INC
SOLEShares100K
TypeSH
Market value$7.96M
1.05%
Sole
100K
Shared
0.00
None
0.00
XOMA CORP DEL
SOLEShares292.59K
TypeSH
Market value$7.78M
1.03%
Sole
292.59K
Shared
0.00
None
0.00
JOURNEY MEDICAL CORP
SOLEShares975K
TypeSH
Market value$7.52M
0.99%
Sole
975K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
HARROW HEALTH INCSOLE | COM | 3.90M | SH | $191.34M 25.24% | 3.90M | 0.00 | 0.00 |
LIQUIDIA CORPORATIONSOLE | COM NEW | 2.44M | SH | $84.98M 11.21% | 2.44M | 0.00 | 0.00 |
ETON PHARMACEUTICALS INCSOLE | COM | 2.86M | SH | $48.36M 6.38% | 2.86M | 0.00 | 0.00 |
RHYTHM PHARMACEUTICALS INCSOLE | COM | 330K | SH | $35.32M 4.66% | 330K | 0.00 | 0.00 |
APOGEE THERAPEUTICS INCSOLE | COM | 388.26K | SH | $29.31M 3.87% | 388.26K | 0.00 | 0.00 |
SANUWAVE HEALTH INCSOLE | COM | 981.27K | SH | $29.28M 3.86% | 981.27K | 0.00 | 0.00 |
STOKE THERAPEUTICS INCSOLE | COM | 695K | SH | $22.06M 2.91% | 695K | 0.00 | 0.00 |
OCULAR THERAPEUTIX INCSOLE | COM | 1.59M | SH | $19.36M 2.55% | 1.59M | 0.00 | 0.00 |
SOL GEL TECHNOLOGIESSOLE | SHS NEW | 453.74K | SH | $19.12M 2.52% | 453.74K | 0.00 | 0.00 |
CG ONCOLOGY INCSOLE | COM | 410K | SH | $17.02M 2.25% | 410K | 0.00 | 0.00 |
TG THERAPEUTICS INCSOLE | COM | 535K | SH | $15.95M 2.10% | 535K | 0.00 | 0.00 |
DISC MEDICINE INCSOLE | COM | 200K | SH | $15.88M 2.10% | 200K | 0.00 | 0.00 |
REZOLUTE INCSOLE | COM NEW | 6.29M | SH | $14.84M 1.96% | 6.29M | 0.00 | 0.00 |
CRESCENT BIOPHARMA INCSOLE | COM | 1.18M | SH | $13.97M 1.84% | 1.18M | 0.00 | 0.00 |
ALKERMES PLCSOLE | SHS | 490K | SH | $13.71M 1.81% | 490K | 0.00 | 0.00 |
ALPHA COGNITION INCSOLE | COM NEW | 2.07M | SH | $13.46M 1.78% | 2.07M | 0.00 | 0.00 |
ANNEXON INCSOLE | COM | 2.60M | SH | $13.05M 1.72% | 2.60M | 0.00 | 0.00 |
EDGEWISE THERAPEUTICS INCSOLE | COM | 500K | SH | $12.41M 1.64% | 500K | 0.00 | 0.00 |
CODEXIS INCSOLE | COM | 6.79M | SH | $11.07M 1.46% | 6.79M | 0.00 | 0.00 |
PROTAGONIST THERAPEUTICS INCSOLE | COM | 105K | SH | $9.17M 1.21% | 105K | 0.00 | 0.00 |
GOSSAMER BIO INCSOLE | COM | 2.72M | SH | $8.43M 1.11% | 2.72M | 0.00 | 0.00 |
MBX BIOSCIENCES INCSOLE | COM | 260K | SH | $8.20M 1.08% | 260K | 0.00 | 0.00 |
REVOLUTION MEDICINES INCSOLE | COM | 100K | SH | $7.96M 1.05% | 100K | 0.00 | 0.00 |
XOMA CORP DELSOLE | COM NEW | 292.59K | SH | $7.78M 1.03% | 292.59K | 0.00 | 0.00 |
JOURNEY MEDICAL CORPSOLE | COM | 975K | SH | $7.52M 0.99% | 975K | 0.00 | 0.00 |
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