MONIA BRETT P

PrivateCIK: 1537529
Location

CARLSBAD, CA

MONIA BRETT P (Chief Operating Officer) sold 25.9% of their position (85.64K shares) of IONIS PHARMACEUTICALS INC on the open market

Open‑market sale worth $6.83M — a significant reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 3 sales
InsiderMONIA BRETT PCIK 1537529
Officer· Chief Operating Officer
Since Jul 2018
-85.64K
Net shares
Net seller
$6.83M
Total sold
3
Open market trades
0B · 3S
9
Total transactions
85.64K acquired · 171.27K disposed
Non-Derivative Transactions6

Common Stock

Direct
M · Option Exercise

Shares

+14.56K

Price / share

$32.60

Trade value

$474.82K

% of position

5.9%
6/24/2026
245.57K260.14K

Common Stock

Direct
S · Sale

Shares

14.56K

Price / share

$78.41

Trade value

$1.14M

% of position

5.6%
6/24/2026
260.14K245.57K

Common Stock

Direct
M · Option Exercise

Shares

+21.07K

Price / share

$32.60

Trade value

$686.95K

% of position

8.6%
6/25/2026
245.57K266.64K

Common Stock

Direct
S · Sale

Shares

21.07K

Price / share

$78.49

Trade value

$1.65M

% of position

7.9%
6/25/2026
266.64K245.57K

Common Stock

Direct
M · Option Exercise

Shares

+50K

Price / share

$56.78

Trade value

$2.84M

% of position

20.4%
6/26/2026
245.57K295.57K

Common Stock

Direct
S · Sale

Shares

50K

Price / share

$80.59

Trade value

$4.03M

% of position

16.9%
6/26/2026
295.57K245.57K
Total

Net shares

+0.00

Net value

-$2.82M

Derivative Transactions3

Non-Qualified Stock Option (right to buy)

Direct
M · Option Exercise
Converts to

Common Stock

14.56K shares

Shares

14.56K

Strike price

32.6

Held after

21.07K

Exercisable

6/24/2026

Non-Qualified Stock Option (right to buy)

Direct
M · Option Exercise
Converts to

Common Stock

21.07K shares

Shares

21.07K

Strike price

32.6

Held after

0.00

Exercisable

6/25/2026

Non-Qualified Stock Option (right to buy)

Direct
M · Option Exercise
Converts to

Common Stock

50K shares

Shares

50K

Strike price

56.78

Held after

99.87K

Exercisable

6/26/2026