MILANOVA TSVETA (Chief Commercial Officer) sold 6.5% of their position (2.87K shares) of AGIOS PHARMACEUTICALS, INC. on the open market

Open‑market sale worth $83.1K — a moderate reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 2 sales

MILANOVA TSVETA

Filed: 3/3/2026ACC: 0001439222-26-000036

InsiderMILANOVA TSVETACIK 1957180

→

IssuerAGIOS PHARMACEUTICALS, INC.CIK 1439222

Officer· Chief Commercial Officer

Since Mar 2026

+63.13K

Net shares

Net buyer

$83.1K

Total sold

Open market trades

0B · 2S

Total transactions

75.67K acquired · 12.53K disposed

Non-Derivative Transactions4

Common stock

Direct

M · Option Exercise

+5.67K

Price / share

—

Trade value

—

% of position

16.3%

3/2/2026

34.79K→40.46K

Common stock

Direct

S · Sale

−1.68K

Price / share

$28.96

Trade value

$48.68K

% of position

4.2%

3/2/2026

40.46K→38.78K

Common stock

Direct

M · Option Exercise

+4K

Price / share

—

Trade value

—

% of position

10.3%

3/2/2026

38.78K→42.78K

Common stock

Direct

S · Sale

−1.19K

Price / share

$28.96

Trade value

$34.38K

% of position

2.8%

3/2/2026

42.78K→41.59K

Total

Net shares

+6.80K

Net value

-$83.06K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common stock Direct	3/2/2026	M · Option Exercise	+5.67K	—	—	16.3%	34.79K	40.46K
Common stock Direct	3/2/2026	S · Sale	−1.68K	$28.96	$48.68K	4.2%	40.46K	38.78K
Common stock Direct	3/2/2026	M · Option Exercise	+4K	—	—	10.3%	38.78K	42.78K
Common stock Direct	3/2/2026	S · Sale	−1.19K	$28.96	$34.38K	2.8%	42.78K	41.59K
Total			+6.80K		-$83.06K

Derivative Transactions4

Restricted stock units

Direct

A · Award

Converts to

Common stock

14K shares

+14K

Strike price

Held after

14K

Exercisable

—

3/1/2026

Stock options (right to buy)

Direct

A · Award

Converts to

Common stock

52K shares

+52K

Strike price

30.23

Held after

52K

Exercisable

—

3/1/2026

Restricted stock units

Direct

M · Option Exercise

Converts to

Common stock

5.67K shares

−5.67K

Strike price

Held after

5.67K

Exercisable

—

3/2/2026

Restricted stock units

Direct

M · Option Exercise

Converts to

Common stock

4K shares

−4K

Strike price

Held after

Exercisable

—

3/2/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Restricted stock units Direct	Common stock14K shares	3/1/2026	A · Award	+14K		—	14K
Stock options (right to buy) Direct	Common stock52K shares	3/1/2026	A · Award	+52K	30.23	—	52K
Restricted stock units Direct	Common stock5.67K shares	3/2/2026	M · Option Exercise	−5.67K		—	5.67K
Restricted stock units Direct	Common stock4K shares	3/2/2026	M · Option Exercise	−4K		—	8K