MAYES PATRICK A (EVP & Chief Scientific Officer) sold 43.8% of their position (47.95K shares) of INCYTE CORP on the open market

Open‑market sale worth $5.73M — a major position exit. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 12 sales

MAYES PATRICK A

Filed: 8/4/2026ACC: 0002079962-26-000013

InsiderMAYES PATRICK ACIK 2079962

→

IssuerINCYTE CORPCIK 879169

Officer· EVP & Chief Scientific Officer

Since Jul 2025

-47.95K

Net shares

Net seller

$5.73M

Total sold

Open market trades

0B · 12S

Total transactions

45.77K acquired · 93.72K disposed

Non-Derivative Transactions28

Common Stock

Direct

M · Option Exercise

+2.92K

Price / share

$61.18

Trade value

$178.52K

% of position

4.6%

7/31/2026

63.63K→66.55K

Common Stock

Direct

M · Option Exercise

+2.28K

Price / share

$64.25

Trade value

$146.75K

% of position

3.4%

7/31/2026

66.55K→68.83K

Common Stock

Direct

M · Option Exercise

+2.71K

Price / share

$61.76

Trade value

$167.31K

% of position

3.9%

7/31/2026

68.83K→71.54K

Common Stock

Direct

M · Option Exercise

+3.15K

Price / share

$68.62

Trade value

$216.02K

% of position

4.4%

7/31/2026

71.54K→74.69K

Common Stock

Direct

M · Option Exercise

+2.07K

Price / share

$71.93

Trade value

$149.04K

% of position

2.8%

7/31/2026

74.69K→76.76K

Common Stock

Direct

M · Option Exercise

+9.46K

Price / share

$72.27

Trade value

$683.60K

% of position

12.3%

7/31/2026

76.76K→86.22K

Common Stock

Direct

M · Option Exercise

+2.62K

Price / share

$74.78

Trade value

$196.15K

% of position

3.0%

7/31/2026

86.22K→88.84K

Common Stock

Direct

M · Option Exercise

+2.86K

Price / share

$77.67

Trade value

$222.45K

% of position

3.2%

7/31/2026

88.84K→91.70K

Common Stock

Direct

M · Option Exercise

+1.64K

Price / share

$80.50

Trade value

$132.26K

% of position

1.8%

7/31/2026

91.70K→93.35K

Common Stock

Direct

M · Option Exercise

+3.02K

Price / share

$83.20

Trade value

$251.51K

% of position

3.2%

7/31/2026

93.35K→96.37K

Common Stock

Direct

M · Option Exercise

+2.62K

Price / share

$83.58

Trade value

$219.23K

% of position

2.7%

7/31/2026

96.37K→98.99K

Common Stock

Direct

M · Option Exercise

+1.64K

Price / share

$85.01

Trade value

$139.59K

% of position

1.7%

7/31/2026

98.99K→100.64K

Common Stock

Direct

M · Option Exercise

+2.29K

Price / share

$90.56

Trade value

$207.65K

% of position

2.3%

7/31/2026

100.64K→102.93K

Common Stock

Direct

M · Option Exercise

+85.00

Price / share

$106.47

Trade value

$9.05K

% of position

0.1%

7/31/2026

102.93K→103.01K

Common Stock

Direct

M · Option Exercise

+326.00

Price / share

$105.43

Trade value

$34.37K

% of position

0.3%

7/31/2026

103.01K→103.34K

Common Stock

Direct

S · Sale

−14.66K

Price / share

$119.46

Trade value

$1.75M

% of position

14.2%

7/31/2026

103.34K→88.68K

Common Stock

Direct

S · Sale

−5.33K

Price / share

$119.42

Trade value

$636.75K

% of position

6.0%

7/31/2026

88.68K→83.35K

Common Stock

Direct

S · Sale

−2.19K

Price / share

$119.47

Trade value

$261.28K

% of position

2.6%

7/31/2026

83.35K→81.16K

Common Stock

Direct

S · Sale

−6.17K

Price / share

$119.43

Trade value

$737K

% of position

7.6%

7/31/2026

81.16K→74.99K

Common Stock

Direct

S · Sale

−4.70K

Price / share

$119.39

Trade value

$560.54K

% of position

6.3%

7/31/2026

74.99K→70.29K

Common Stock

Direct

S · Sale

−2.86K

Price / share

$119.40

Trade value

$341.96K

% of position

4.1%

7/31/2026

70.29K→67.43K

Common Stock

Direct

S · Sale

−1.64K

Price / share

$119.51

Trade value

$196.35K

% of position

2.4%

7/31/2026

67.43K→65.79K

Common Stock

Direct

S · Sale

−1.64K

Price / share

$119.38

Trade value

$196.02K

% of position

2.5%

7/31/2026

65.79K→64.14K

Common Stock

Direct

S · Sale

−85.00

Price / share

$122.19

Trade value

$10.39K

% of position

0.1%

7/31/2026

64.14K→64.06K

Common Stock

Direct

S · Sale

−326.00

Price / share

$121.69

Trade value

$39.67K

% of position

0.5%

7/31/2026

64.06K→63.73K

Common Stock

Direct

S · Sale

−2.29K

Price / share

$119.41

Trade value

$273.81K

% of position

3.6%

7/31/2026

63.73K→61.44K

Common Stock

Direct

M · Option Exercise

+6.05K

Price / share

$105.43

Trade value

$638.38K

% of position

9.9%

8/3/2026

61.44K→67.50K

Common Stock

Direct

S · Sale

−6.05K

Price / share

$120.43

Trade value

$729.20K

% of position

9.0%

8/3/2026

67.50K→61.44K

Total

Net shares

−2.19K

Net value

-$2.14M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	7/31/2026	M · Option Exercise	+2.92K	$61.18	$178.52K	4.6%	63.63K	66.55K
Common Stock Direct	7/31/2026	M · Option Exercise	+2.28K	$64.25	$146.75K	3.4%	66.55K	68.83K
Common Stock Direct	7/31/2026	M · Option Exercise	+2.71K	$61.76	$167.31K	3.9%	68.83K	71.54K
Common Stock Direct	7/31/2026	M · Option Exercise	+3.15K	$68.62	$216.02K	4.4%	71.54K	74.69K
Common Stock Direct	7/31/2026	M · Option Exercise	+2.07K	$71.93	$149.04K	2.8%	74.69K	76.76K
Common Stock Direct	7/31/2026	M · Option Exercise	+9.46K	$72.27	$683.60K	12.3%	76.76K	86.22K
Common Stock Direct	7/31/2026	M · Option Exercise	+2.62K	$74.78	$196.15K	3.0%	86.22K	88.84K
Common Stock Direct	7/31/2026	M · Option Exercise	+2.86K	$77.67	$222.45K	3.2%	88.84K	91.70K
Common Stock Direct	7/31/2026	M · Option Exercise	+1.64K	$80.50	$132.26K	1.8%	91.70K	93.35K
Common Stock Direct	7/31/2026	M · Option Exercise	+3.02K	$83.20	$251.51K	3.2%	93.35K	96.37K
Common Stock Direct	7/31/2026	M · Option Exercise	+2.62K	$83.58	$219.23K	2.7%	96.37K	98.99K
Common Stock Direct	7/31/2026	M · Option Exercise	+1.64K	$85.01	$139.59K	1.7%	98.99K	100.64K
Common Stock Direct	7/31/2026	M · Option Exercise	+2.29K	$90.56	$207.65K	2.3%	100.64K	102.93K
Common Stock Direct	7/31/2026	M · Option Exercise	+85.00	$106.47	$9.05K	0.1%	102.93K	103.01K
Common Stock Direct	7/31/2026	M · Option Exercise	+326.00	$105.43	$34.37K	0.3%	103.01K	103.34K
Common Stock Direct	7/31/2026	S · Sale	−14.66K	$119.46	$1.75M	14.2%	103.34K	88.68K
Common Stock Direct	7/31/2026	S · Sale	−5.33K	$119.42	$636.75K	6.0%	88.68K	83.35K
Common Stock Direct	7/31/2026	S · Sale	−2.19K	$119.47	$261.28K	2.6%	83.35K	81.16K
Common Stock Direct	7/31/2026	S · Sale	−6.17K	$119.43	$737K	7.6%	81.16K	74.99K
Common Stock Direct	7/31/2026	S · Sale	−4.70K	$119.39	$560.54K	6.3%	74.99K	70.29K
Common Stock Direct	7/31/2026	S · Sale	−2.86K	$119.40	$341.96K	4.1%	70.29K	67.43K
Common Stock Direct	7/31/2026	S · Sale	−1.64K	$119.51	$196.35K	2.4%	67.43K	65.79K
Common Stock Direct	7/31/2026	S · Sale	−1.64K	$119.38	$196.02K	2.5%	65.79K	64.14K
Common Stock Direct	7/31/2026	S · Sale	−85.00	$122.19	$10.39K	0.1%	64.14K	64.06K
Common Stock Direct	7/31/2026	S · Sale	−326.00	$121.69	$39.67K	0.5%	64.06K	63.73K
Common Stock Direct	7/31/2026	S · Sale	−2.29K	$119.41	$273.81K	3.6%	63.73K	61.44K
Common Stock Direct	8/3/2026	M · Option Exercise	+6.05K	$105.43	$638.38K	9.9%	61.44K	67.50K
Common Stock Direct	8/3/2026	S · Sale	−6.05K	$120.43	$729.20K	9.0%	67.50K	61.44K
Total			−2.19K		-$2.14M

Derivative Transactions16

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.92K shares

−2.92K

Strike price

61.18

Held after

1.33K

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.28K shares

−2.28K

Strike price

64.25

Held after

2.94K

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.71K shares

−2.71K

Strike price

61.76

Held after

1.23K

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.15K shares

−3.15K

Strike price

68.62

Held after

0.00

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.07K shares

−2.07K

Strike price

71.93

Held after

2.67K

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

9.46K shares

−9.46K

Strike price

72.27

Held after

0.00

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.62K shares

−2.62K

Strike price

74.78

Held after

0.00

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.86K shares

−2.86K

Strike price

77.67

Held after

191.00

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

1.64K shares

−1.64K

Strike price

80.50

Held after

0.00

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.02K shares

−3.02K

Strike price

83.20

Held after

202.00

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.62K shares

−2.62K

Strike price

83.58

Held after

0.00

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

1.64K shares

−1.64K

Strike price

85.01

Held after

0.00

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.29K shares

−2.29K

Strike price

90.56

Held after

0.00

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

85.00 shares

−85.00

Strike price

106.47

Held after

2.21K

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

326.00 shares

−326.00

Strike price

105.43

Held after

6.05K

Exercisable

—

7/31/2026

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

6.05K shares

−6.05K

Strike price

105.43

Held after

0.00

Exercisable

—

8/3/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Employee Stock Option (right to buy) Direct	Common Stock2.92K shares	7/31/2026	M · Option Exercise	−2.92K	61.18	—	1.33K
Employee Stock Option (right to buy) Direct	Common Stock2.28K shares	7/31/2026	M · Option Exercise	−2.28K	64.25	—	2.94K
Employee Stock Option (right to buy) Direct	Common Stock2.71K shares	7/31/2026	M · Option Exercise	−2.71K	61.76	—	1.23K
Employee Stock Option (right to buy) Direct	Common Stock3.15K shares	7/31/2026	M · Option Exercise	−3.15K	68.62	—	0.00
Employee Stock Option (right to buy) Direct	Common Stock2.07K shares	7/31/2026	M · Option Exercise	−2.07K	71.93	—	2.67K
Employee Stock Option (right to buy) Direct	Common Stock9.46K shares	7/31/2026	M · Option Exercise	−9.46K	72.27	—	0.00
Employee Stock Option (right to buy) Direct	Common Stock2.62K shares	7/31/2026	M · Option Exercise	−2.62K	74.78	—	0.00
Employee Stock Option (right to buy) Direct	Common Stock2.86K shares	7/31/2026	M · Option Exercise	−2.86K	77.67	—	191.00
Employee Stock Option (right to buy) Direct	Common Stock1.64K shares	7/31/2026	M · Option Exercise	−1.64K	80.50	—	0.00
Employee Stock Option (right to buy) Direct	Common Stock3.02K shares	7/31/2026	M · Option Exercise	−3.02K	83.20	—	202.00
Employee Stock Option (right to buy) Direct	Common Stock2.62K shares	7/31/2026	M · Option Exercise	−2.62K	83.58	—	0.00
Employee Stock Option (right to buy) Direct	Common Stock1.64K shares	7/31/2026	M · Option Exercise	−1.64K	85.01	—	0.00
Employee Stock Option (right to buy) Direct	Common Stock2.29K shares	7/31/2026	M · Option Exercise	−2.29K	90.56	—	0.00
Employee Stock Option (right to buy) Direct	Common Stock85.00 shares	7/31/2026	M · Option Exercise	−85.00	106.47	—	2.21K
Employee Stock Option (right to buy) Direct	Common Stock326.00 shares	7/31/2026	M · Option Exercise	−326.00	105.43	—	6.05K
Employee Stock Option (right to buy) Direct	Common Stock6.05K shares	8/3/2026	M · Option Exercise	−6.05K	105.43	—	0.00