MACLEAN MICHAEL F (Chief Financial Officer) reported 1 transaction at AVIDITY BIOSCIENCES, INC.

Review the transaction codes below to understand the nature of each event.

MACLEAN MICHAEL F

Filed: 2/27/2026ACC: 0001193125-26-082300

InsiderMACLEAN MICHAEL FCIK 1383731

→

IssuerAVIDITY BIOSCIENCES, INC.CIK 1599901

Officer· Chief Financial Officer

Since Jun 2020

-721.35K

Net shares

Net seller

$0.00

Total acquired

Open market trades

0B · 0S

Total transactions

721.35K disposed

Non-Derivative Transactions1

Common Stock

Direct

D · Disposition

−133.98K

Price / share

—

Trade value

—

% of position

New position

2/27/2026

133.98K→0.00

Total

Net shares

−133.98K

Net value

$0.00

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	2/27/2026	D · Disposition	−133.98K	—	—	New position	133.98K	0.00
Total			−133.98K		$0.00

Derivative Transactions6

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

92K shares

−92K

Strike price

22.34

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

131.25K shares

−131.25K

Strike price

14.22

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

148K shares

−148K

Strike price

22.47

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

60.13K shares

−60.13K

Strike price

6.57

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

106K shares

−106K

Strike price

10.16

Held after

0.00

Exercisable

—

2/27/2026

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

50K shares

−50K

Strike price

31.42

Held after

0.00

Exercisable

—

2/27/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable
Stock Option (Right to Buy) Direct	Common Stock92K shares	2/27/2026	D · Disposition	−92K	22.34	—
Stock Option (Right to Buy) Direct	Common Stock131.25K shares	2/27/2026	D · Disposition	−131.25K	14.22	—
Stock Option (Right to Buy) Direct	Common Stock148K shares	2/27/2026	D · Disposition	−148K	22.47	—
Stock Option (Right to Buy) Direct	Common Stock60.13K shares	2/27/2026	D · Disposition	−60.13K	6.57	—
Stock Option (Right to Buy) Direct	Common Stock106K shares	2/27/2026	D · Disposition	−106K	10.16	—
Stock Option (Right to Buy) Direct	Common Stock50K shares	2/27/2026	D · Disposition	−50K	31.42	—