LOSCALZO JOSEPH

PrivateCIK: 1276128
Location

CARLSBAD, CA

LOSCALZO JOSEPH sold 68.0% of their position (77.29K shares) of IONIS PHARMACEUTICALS INC on the open market

Open‑market sale worth $5.80M — a major position exit. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 2 sales
InsiderLOSCALZO JOSEPHCIK 1276128
Director
Since Mar 2026
-77.29K
Net shares
Net seller
$5.80M
Total sold
2
Open market trades
0B · 2S
14
Total transactions
77.29K acquired · 154.58K disposed
Non-Derivative Transactions8

Common Stock

Direct
M · Option Exercise

Shares

+10.97K

Price / share

$38.06

Trade value

$417.44K

% of position

30.2%
5/4/2026
36.33K47.30K

Common Stock

Direct
M · Option Exercise

Shares

+12K

Price / share

$40.05

Trade value

$480.60K

% of position

25.4%
5/4/2026
47.30K59.30K

Common Stock

Direct
M · Option Exercise

Shares

+10.32K

Price / share

$41.08

Trade value

$423.99K

% of position

17.4%
5/4/2026
59.30K69.62K

Common Stock

Direct
M · Option Exercise

Shares

+16K

Price / share

$42.88

Trade value

$686.08K

% of position

23.0%
5/4/2026
69.62K85.62K

Common Stock

Direct
M · Option Exercise

Shares

+12K

Price / share

$60.20

Trade value

$722.40K

% of position

14.0%
5/4/2026
85.62K97.62K

Common Stock

Direct
M · Option Exercise

Shares

+16K

Price / share

$64.80

Trade value

$1.04M

% of position

16.4%
5/4/2026
97.62K113.62K

Common Stock

Direct
S · Sale

Shares

59.51K

Price / share

$74.90

Trade value

$4.46M

% of position

52.4%
5/4/2026
113.62K54.11K

Common Stock

Direct
S · Sale

Shares

17.78K

Price / share

$75.58

Trade value

$1.34M

% of position

32.9%
5/4/2026
54.11K36.33K
Total

Net shares

+0.00

Net value

-$2.03M

Derivative Transactions6

Non-Qualified Stock Option (right to buy)

Direct
M · Option Exercise
Converts to

Common Stock

10.97K shares

Shares

10.97K

Strike price

38.06

Held after

0.00

Exercisable

5/4/2026

Non-Qualified Stock Option (right to buy)

Direct
M · Option Exercise
Converts to

Common Stock

12K shares

Shares

12K

Strike price

40.05

Held after

0.00

Exercisable

5/4/2026

Non-Qualified Stock Option (right to buy)

Direct
M · Option Exercise
Converts to

Common Stock

10.32K shares

Shares

10.32K

Strike price

41.08

Held after

0.00

Exercisable

5/4/2026

Non-Qualified Stock Option (right to buy)

Direct
M · Option Exercise
Converts to

Common Stock

16K shares

Shares

16K

Strike price

42.88

Held after

0.00

Exercisable

5/4/2026

Non-Qualified Stock Option (right to buy)

Direct
M · Option Exercise
Converts to

Common Stock

12K shares

Shares

12K

Strike price

60.2

Held after

0.00

Exercisable

5/4/2026

Non-Qualified Stock Option (right to buy)

Direct
M · Option Exercise
Converts to

Common Stock

16K shares

Shares

16K

Strike price

64.8

Held after

0.00

Exercisable

5/4/2026
LOSCALZO JOSEPH — Insider Transaction (Form 4) Filed May 6, 2026 | Finecho