LESAGE ANNE (Chief Early Development) sold 26.5% of their position (48.30K shares) of PHARVARIS N.V. on the open market

Open‑market sale worth $1.46M — a significant reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 5 sales

LESAGE ANNE

Filed: 5/1/2026ACC: 0001193125-26-201925

InsiderLESAGE ANNECIK 1973705

→

IssuerPHARVARIS N.V.CIK 1830487

Officer· Chief Early Development

Since Mar 2026

-48.30K

Net shares

Net seller

$1.46M

Total sold

Open market trades

0B · 5S

Total transactions

25.40K acquired · 73.70K disposed

Non-Derivative Transactions8

Common Stock

Direct

M · Option Exercise

+3.70K

Price / share

$2.59

Trade value

$9.58K

% of position

6.6%

4/29/2026

56.45K→60.15K

Common Stock

Direct

S · Sale

−3.70K

Price / share

$30.08

Trade value

$111.28K

% of position

6.2%

4/29/2026

60.15K→56.45K

Common Stock

Indirect

S · Sale

−3.70K

Price / share

$30.06

Trade value

$111.23K

% of position

2.4%

4/29/2026

156.87K→153.17K

Common Stock

Direct

M · Option Exercise

+3.70K

Price / share

$2.59

Trade value

$9.58K

% of position

6.6%

4/30/2026

56.45K→60.15K

Common Stock

Direct

S · Sale

−3.70K

Price / share

$30.26

Trade value

$111.95K

% of position

6.2%

4/30/2026

60.15K→56.45K

Common Stock

Direct

M · Option Exercise

+18K

Price / share

$8.05

Trade value

$144.90K

% of position

31.9%

4/30/2026

56.45K→74.45K

Common Stock

Direct

S · Sale

−18K

Price / share

$30.26

Trade value

$544.60K

% of position

24.2%

4/30/2026

74.45K→56.45K

Common Stock

Indirect

S · Sale

−19.20K

Price / share

$30.26

Trade value

$580.91K

% of position

12.5%

4/30/2026

153.17K→133.97K

Total

Net shares

−22.90K

Net value

-$1.30M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	4/29/2026	M · Option Exercise	+3.70K	$2.59	$9.58K	6.6%	56.45K	60.15K
Common Stock Direct	4/29/2026	S · Sale	−3.70K	$30.08	$111.28K	6.2%	60.15K	56.45K
Common Stock Indirect	4/29/2026	S · Sale	−3.70K	$30.06	$111.23K	2.4%	156.87K	153.17K
Common Stock Direct	4/30/2026	M · Option Exercise	+3.70K	$2.59	$9.58K	6.6%	56.45K	60.15K
Common Stock Direct	4/30/2026	S · Sale	−3.70K	$30.26	$111.95K	6.2%	60.15K	56.45K
Common Stock Direct	4/30/2026	M · Option Exercise	+18K	$8.05	$144.90K	31.9%	56.45K	74.45K
Common Stock Direct	4/30/2026	S · Sale	−18K	$30.26	$544.60K	24.2%	74.45K	56.45K
Common Stock Indirect	4/30/2026	S · Sale	−19.20K	$30.26	$580.91K	12.5%	153.17K	133.97K
Total			−22.90K		-$1.30M

Derivative Transactions3

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.70K shares

−3.70K

Strike price

2.59

Held after

12.77K

Exercisable

—

4/29/2026

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.70K shares

−3.70K

Strike price

2.59

Held after

9.07K

Exercisable

—

4/30/2026

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

18K shares

−18K

Strike price

8.05

Held after

82K

Exercisable

—

4/30/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Stock Option (Right to Buy) Direct	Common Stock3.70K shares	4/29/2026	M · Option Exercise	−3.70K	2.59	—	12.77K
Stock Option (Right to Buy) Direct	Common Stock3.70K shares	4/30/2026	M · Option Exercise	−3.70K	2.59	—	9.07K
Stock Option (Right to Buy) Direct	Common Stock18K shares	4/30/2026	M · Option Exercise	−18K	8.05	—	82K