LEPROUST EMILY M. (President & CEO) sold 0.8% of their position (4.55K shares) of TWIST BIOSCIENCE CORP on the open market

Open‑market sale worth $919.4K — a minor trim. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 8 sales

LEPROUST EMILY M.

Filed: 10/7/2026ACC: 0001214659-26-012647

InsiderLEPROUST EMILY M.CIK 1753655

→

IssuerTWIST BIOSCIENCE CORPCIK 1581280

DirectorOfficer· President & CEO

Since Oct 2018

-4.55K

Net shares

Net seller

$919.4K

Total sold

Open market trades

0B · 8S

Total transactions

4.55K disposed

Non-Derivative Transactions8

Common Stock

Direct

S · Sale

−1.84K

Price / share

$200.44

Trade value

$368.81K

% of position

0.3%

10/5/2026

567.31K→565.47K

Common Stock

Direct

S · Sale

−481.00

Price / share

$201.26

Trade value

$96.80K

% of position

0.1%

10/5/2026

565.47K→564.99K

Common Stock

Direct

S · Sale

−1.02K

Price / share

$202.32

Trade value

$205.76K

% of position

0.2%

10/5/2026

564.99K→563.97K

Common Stock

Direct

S · Sale

−432.00

Price / share

$203.61

Trade value

$87.96K

% of position

0.1%

10/5/2026

563.97K→563.54K

Common Stock

Direct

S · Sale

−290.00

Price / share

$204.80

Trade value

$59.39K

% of position

0.1%

10/5/2026

563.54K→563.25K

Common Stock

Direct

S · Sale

−297.00

Price / share

$205.78

Trade value

$61.12K

% of position

0.1%

10/5/2026

563.25K→562.95K

Common Stock

Direct

S · Sale

−146.00

Price / share

$206.84

Trade value

$30.20K

% of position

0.0%

10/5/2026

562.95K→562.80K

Common Stock

Direct

S · Sale

−45.00

Price / share

$207.46

Trade value

$9.34K

% of position

0.0%

10/5/2026

562.80K→562.76K

Total

Net shares

−4.55K

Net value

-$919.37K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	10/5/2026	S · Sale	−1.84K	$200.44	$368.81K	0.3%	567.31K	565.47K
Common Stock Direct	10/5/2026	S · Sale	−481.00	$201.26	$96.80K	0.1%	565.47K	564.99K
Common Stock Direct	10/5/2026	S · Sale	−1.02K	$202.32	$205.76K	0.2%	564.99K	563.97K
Common Stock Direct	10/5/2026	S · Sale	−432.00	$203.61	$87.96K	0.1%	563.97K	563.54K
Common Stock Direct	10/5/2026	S · Sale	−290.00	$204.80	$59.39K	0.1%	563.54K	563.25K
Common Stock Direct	10/5/2026	S · Sale	−297.00	$205.78	$61.12K	0.1%	563.25K	562.95K
Common Stock Direct	10/5/2026	S · Sale	−146.00	$206.84	$30.20K	0.0%	562.95K	562.80K
Common Stock Direct	10/5/2026	S · Sale	−45.00	$207.46	$9.34K	0.0%	562.80K	562.76K
Total			−4.55K		-$919.37K

Derivative Transactions0

No derivative transactions reported

Non-Derivative Holdings (Post-Transaction)0

No non-derivative holdings reported

Derivative Holdings (Post-Transaction)2

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

64.95K

Shares owned

64.95K

Exercise price

67.85

Expiration

—

Exercise window

—

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

131.29K

Shares owned

131.29K

Exercise price

23.33

Expiration

—

Exercise window

—

Total

Underlying

196.24K

Owned

196.24K

Security	Underlying	Exercise Price	Exercise Window	Expiration	Underlying Shares	Shares Owned
Employee Stock Option (right to buy) Direct	Common Stock	67.85	—	—	64.95K	64.95K
Employee Stock Option (right to buy) Direct	Common Stock	23.33	—	—	131.29K	131.29K
Total					196.24K	196.24K