LEPROUST EMILY M. (President & CEO) sold 0.8% of their position (5.20K shares) of TWIST BIOSCIENCE CORP on the open market

Open‑market sale worth $922.9K — a minor trim. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 10 sales

LEPROUST EMILY M.

Filed: 9/25/2026ACC: 0001214659-26-011980

InsiderLEPROUST EMILY M.CIK 1753655

→

IssuerTWIST BIOSCIENCE CORPCIK 1581280

DirectorOfficer· President & CEO

Since Oct 2018

-5.20K

Net shares

Net seller

$922.9K

Total sold

Open market trades

0B · 10S

Total transactions

5.20K disposed

Non-Derivative Transactions10

Common Stock

Direct

S · Sale

−2.48K

Price / share

$175.23

Trade value

$435.45K

% of position

0.4%

9/24/2026

618.90K→616.42K

Common Stock

Direct

S · Sale

−945.00

Price / share

$176.39

Trade value

$166.69K

% of position

0.2%

9/24/2026

616.42K→615.47K

Common Stock

Direct

S · Sale

−164.00

Price / share

$177.17

Trade value

$29.06K

% of position

0.0%

9/24/2026

615.47K→615.31K

Common Stock

Direct

S · Sale

−330.00

Price / share

$178.67

Trade value

$58.96K

% of position

0.1%

9/24/2026

615.31K→614.98K

Common Stock

Direct

S · Sale

−143.00

Price / share

$179.93

Trade value

$25.73K

% of position

0.0%

9/24/2026

614.98K→614.84K

Common Stock

Direct

S · Sale

−515.00

Price / share

$180.39

Trade value

$92.90K

% of position

0.1%

9/24/2026

614.84K→614.32K

Common Stock

Direct

S · Sale

−21.00

Price / share

$181.45

Trade value

$3.81K

% of position

0.0%

9/24/2026

614.32K→614.30K

Common Stock

Direct

S · Sale

−16.00

Price / share

$182.50

Trade value

$2.92K

% of position

0.0%

9/24/2026

614.30K→614.28K

Common Stock

Direct

S · Sale

−501.00

Price / share

$183.76

Trade value

$92.07K

% of position

0.1%

9/24/2026

614.28K→613.78K

Common Stock

Direct

S · Sale

−83.00

Price / share

$184.60

Trade value

$15.32K

% of position

0.0%

9/24/2026

613.78K→613.70K

Total

Net shares

−5.20K

Net value

-$922.91K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	9/24/2026	S · Sale	−2.48K	$175.23	$435.45K	0.4%	618.90K	616.42K
Common Stock Direct	9/24/2026	S · Sale	−945.00	$176.39	$166.69K	0.2%	616.42K	615.47K
Common Stock Direct	9/24/2026	S · Sale	−164.00	$177.17	$29.06K	0.0%	615.47K	615.31K
Common Stock Direct	9/24/2026	S · Sale	−330.00	$178.67	$58.96K	0.1%	615.31K	614.98K
Common Stock Direct	9/24/2026	S · Sale	−143.00	$179.93	$25.73K	0.0%	614.98K	614.84K
Common Stock Direct	9/24/2026	S · Sale	−515.00	$180.39	$92.90K	0.1%	614.84K	614.32K
Common Stock Direct	9/24/2026	S · Sale	−21.00	$181.45	$3.81K	0.0%	614.32K	614.30K
Common Stock Direct	9/24/2026	S · Sale	−16.00	$182.50	$2.92K	0.0%	614.30K	614.28K
Common Stock Direct	9/24/2026	S · Sale	−501.00	$183.76	$92.07K	0.1%	614.28K	613.78K
Common Stock Direct	9/24/2026	S · Sale	−83.00	$184.60	$15.32K	0.0%	613.78K	613.70K
Total			−5.20K		-$922.91K

Derivative Transactions0

No derivative transactions reported

Non-Derivative Holdings (Post-Transaction)0

No non-derivative holdings reported

Derivative Holdings (Post-Transaction)2

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

131.29K

Shares owned

131.29K

Exercise price

23.33

Expiration

—

Exercise window

—

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

64.95K

Shares owned

64.95K

Exercise price

67.85

Expiration

—

Exercise window

—

Total

Underlying

196.24K

Owned

196.24K

Security	Underlying	Exercise Price	Exercise Window	Expiration	Underlying Shares	Shares Owned
Employee Stock Option (right to buy) Direct	Common Stock	23.33	—	—	131.29K	131.29K
Employee Stock Option (right to buy) Direct	Common Stock	67.85	—	—	64.95K	64.95K
Total					196.24K	196.24K