LEPROUST EMILY M. (President & CEO) sold 5.1% of their position (41.57K shares) of TWIST BIOSCIENCE CORP on the open market

Open‑market sale worth $6.32M — a moderate reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 5 sales

LEPROUST EMILY M.

Filed: 8/27/2026ACC: 0001214659-26-010968

InsiderLEPROUST EMILY M.CIK 1753655

→

IssuerTWIST BIOSCIENCE CORPCIK 1581280

DirectorOfficer· President & CEO

Since Oct 2018

-41.57K

Net shares

Net seller

$6.32M

Total sold

Open market trades

0B · 5S

Total transactions

41.57K disposed

Non-Derivative Transactions5

Common Stock

Direct

S · Sale

−12.65K

Price / share

$150.56

Trade value

$1.90M

% of position

1.6%

8/25/2026

812.30K→799.65K

Common Stock

Direct

S · Sale

−12.24K

Price / share

$151.35

Trade value

$1.85M

% of position

1.5%

8/25/2026

799.65K→787.41K

Common Stock

Direct

S · Sale

−6.41K

Price / share

$152.75

Trade value

$979.43K

% of position

0.8%

8/25/2026

787.41K→781K

Common Stock

Direct

S · Sale

−9.18K

Price / share

$153.93

Trade value

$1.41M

% of position

1.2%

8/25/2026

781K→771.82K

Common Stock

Direct

S · Sale

−1.09K

Price / share

$154.45

Trade value

$168.81K

% of position

0.1%

8/25/2026

771.82K→770.73K

Total

Net shares

−41.57K

Net value

-$6.32M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	8/25/2026	S · Sale	−12.65K	$150.56	$1.90M	1.6%	812.30K	799.65K
Common Stock Direct	8/25/2026	S · Sale	−12.24K	$151.35	$1.85M	1.5%	799.65K	787.41K
Common Stock Direct	8/25/2026	S · Sale	−6.41K	$152.75	$979.43K	0.8%	787.41K	781K
Common Stock Direct	8/25/2026	S · Sale	−9.18K	$153.93	$1.41M	1.2%	781K	771.82K
Common Stock Direct	8/25/2026	S · Sale	−1.09K	$154.45	$168.81K	0.1%	771.82K	770.73K
Total			−41.57K		-$6.32M

Derivative Transactions0

No derivative transactions reported

Non-Derivative Holdings (Post-Transaction)0

No non-derivative holdings reported

Derivative Holdings (Post-Transaction)5

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

0.00

Shares owned

0.00

Exercise price

5.95

Expiration

—

Exercise window

—

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

0.00

Shares owned

133.27K

Exercise price

26.66

Expiration

—

Exercise window

—

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

0.00

Shares owned

75.44K

Exercise price

8.82

Expiration

—

Exercise window

—

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

64.95K

Shares owned

64.95K

Exercise price

67.85

Expiration

—

Exercise window

—

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

0.00

Shares owned

131.29K

Exercise price

23.33

Expiration

—

Exercise window

—

Total

Underlying

64.95K

Owned

404.95K

Security	Underlying	Exercise Price	Exercise Window	Expiration	Underlying Shares	Shares Owned
Employee Stock Option (right to buy) Direct	Common Stock	5.95	—	—	0.00	0.00
Employee Stock Option (right to buy) Direct	Common Stock	26.66	—	—	0.00	133.27K
Employee Stock Option (right to buy) Direct	Common Stock	8.82	—	—	0.00	75.44K
Employee Stock Option (right to buy) Direct	Common Stock	67.85	—	—	64.95K	64.95K
Employee Stock Option (right to buy) Direct	Common Stock	23.33	—	—	0.00	131.29K
Total					64.95K	404.95K