LEPROUST EMILY M. (President & CEO) sold 1.9% of their position (16.47K shares) of TWIST BIOSCIENCE CORP on the open market

Open‑market sale worth $1.12M — a minor trim. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 4 sales

LEPROUST EMILY M.

Filed: 6/1/2026ACC: 0001214659-26-006967

InsiderLEPROUST EMILY M.CIK 1753655

→

IssuerTWIST BIOSCIENCE CORPCIK 1581280

DirectorOfficer· President & CEO

Since Oct 2018

-16.47K

Net shares

Net seller

$1.12M

Total sold

Open market trades

0B · 4S

Total transactions

16.47K acquired · 32.94K disposed

Non-Derivative Transactions5

Common Stock

Direct

M · Option Exercise

+16.47K

Price / share

$8.82

Trade value

$145.27K

% of position

1.9%

5/28/2026

846.87K→863.34K

Common Stock

Direct

S · Sale

−1.48K

Price / share

$65.33

Trade value

$96.81K

% of position

0.2%

5/28/2026

863.34K→861.86K

Common Stock

Direct

S · Sale

−900.00

Price / share

$66.85

Trade value

$60.16K

% of position

0.1%

5/28/2026

861.86K→860.96K

Common Stock

Direct

S · Sale

−7.62K

Price / share

$67.95

Trade value

$517.99K

% of position

0.9%

5/28/2026

860.96K→853.34K

Common Stock

Direct

S · Sale

−6.46K

Price / share

$68.61

Trade value

$443.59K

% of position

0.8%

5/28/2026

853.34K→846.87K

Total

Net shares

+0.00

Net value

-$973.29K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	5/28/2026	M · Option Exercise	+16.47K	$8.82	$145.27K	1.9%	846.87K	863.34K
Common Stock Direct	5/28/2026	S · Sale	−1.48K	$65.33	$96.81K	0.2%	863.34K	861.86K
Common Stock Direct	5/28/2026	S · Sale	−900.00	$66.85	$60.16K	0.1%	861.86K	860.96K
Common Stock Direct	5/28/2026	S · Sale	−7.62K	$67.95	$517.99K	0.9%	860.96K	853.34K
Common Stock Direct	5/28/2026	S · Sale	−6.46K	$68.61	$443.59K	0.8%	853.34K	846.87K
Total			+0.00		-$973.29K

Derivative Transactions1

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

16.47K shares

−16.47K

Strike price

8.82

Held after

75.44K

Exercisable

—

5/28/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Employee Stock Option (right to buy) Direct	Common Stock16.47K shares	5/28/2026	M · Option Exercise	−16.47K	8.82	—	75.44K

Non-Derivative Holdings (Post-Transaction)0

No non-derivative holdings reported

Derivative Holdings (Post-Transaction)4

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

0.00

Shares owned

131.29K

Exercise price

23.33

Expiration

—

Exercise window

—

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

0.00

Shares owned

0.00

Exercise price

5.95

Expiration

—

Exercise window

—

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

0.00

Shares owned

266.54K

Exercise price

26.66

Expiration

—

Exercise window

—

Employee Stock Option (right to buy)

Direct

Underlying security

Common Stock

Underlying shares

64.95K

Shares owned

64.95K

Exercise price

67.85

Expiration

—

Exercise window

—

Total

Underlying

64.95K

Owned

462.78K

Security	Underlying	Exercise Price	Exercise Window	Expiration	Underlying Shares	Shares Owned
Employee Stock Option (right to buy) Direct	Common Stock	23.33	—	—	0.00	131.29K
Employee Stock Option (right to buy) Direct	Common Stock	5.95	—	—	0.00	0.00
Employee Stock Option (right to buy) Direct	Common Stock	26.66	—	—	0.00	266.54K
Employee Stock Option (right to buy) Direct	Common Stock	67.85	—	—	64.95K	64.95K
Total					64.95K	462.78K