JONES CECILIA (Chief Financial Officer) sold 9.3% of their position (5.04K shares) of AGIOS PHARMACEUTICALS, INC. on the open market

Open‑market sale worth $145.8K — a moderate reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 4 sales

JONES CECILIA

Filed: 3/3/2026ACC: 0001439222-26-000038

InsiderJONES CECILIACIK 1840056

→

IssuerAGIOS PHARMACEUTICALS, INC.CIK 1439222

Officer· Chief Financial Officer

Since Mar 2026

+60.97K

Net shares

Net buyer

$145.8K

Total sold

Open market trades

0B · 4S

Total transactions

82.97K acquired · 22K disposed

Non-Derivative Transactions8

Common stock

Direct

M · Option Exercise

+2K

Price / share

—

Trade value

—

% of position

5.3%

3/2/2026

37.39K→39.39K

Common stock

Direct

S · Sale

−594.00

Price / share

$28.96

Trade value

$17.20K

% of position

1.5%

3/2/2026

39.39K→38.80K

Common stock

Direct

M · Option Exercise

+5.67K

Price / share

—

Trade value

—

% of position

14.6%

3/2/2026

38.80K→44.47K

Common stock

Direct

S · Sale

−1.68K

Price / share

$28.96

Trade value

$48.68K

% of position

3.8%

3/2/2026

44.47K→42.78K

Common stock

Direct

M · Option Exercise

+4K

Price / share

—

Trade value

—

% of position

9.3%

3/2/2026

42.78K→46.78K

Common stock

Direct

S · Sale

−1.19K

Price / share

$28.96

Trade value

$34.38K

% of position

2.5%

3/2/2026

46.78K→45.60K

Common stock

Direct

M · Option Exercise

+5.30K

Price / share

—

Trade value

—

% of position

11.6%

3/2/2026

45.60K→50.90K

Common stock

Direct

S · Sale

−1.57K

Price / share

$28.96

Trade value

$45.55K

% of position

3.1%

3/2/2026

50.90K→49.33K

Total

Net shares

+11.93K

Net value

-$145.81K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common stock Direct	3/2/2026	M · Option Exercise	+2K	—	—	5.3%	37.39K	39.39K
Common stock Direct	3/2/2026	S · Sale	−594.00	$28.96	$17.20K	1.5%	39.39K	38.80K
Common stock Direct	3/2/2026	M · Option Exercise	+5.67K	—	—	14.6%	38.80K	44.47K
Common stock Direct	3/2/2026	S · Sale	−1.68K	$28.96	$48.68K	3.8%	44.47K	42.78K
Common stock Direct	3/2/2026	M · Option Exercise	+4K	—	—	9.3%	42.78K	46.78K
Common stock Direct	3/2/2026	S · Sale	−1.19K	$28.96	$34.38K	2.5%	46.78K	45.60K
Common stock Direct	3/2/2026	M · Option Exercise	+5.30K	—	—	11.6%	45.60K	50.90K
Common stock Direct	3/2/2026	S · Sale	−1.57K	$28.96	$45.55K	3.1%	50.90K	49.33K
Total			+11.93K		-$145.81K

Derivative Transactions6

Restricted stock units

Direct

A · Award

Converts to

Common stock

14K shares

+14K

Strike price

Held after

14K

Exercisable

—

3/1/2026

Stock options (right to buy)

Direct

A · Award

Converts to

Common stock

52K shares

+52K

Strike price

30.23

Held after

52K

Exercisable

—

3/1/2026

Restricted stock units

Direct

M · Option Exercise

Converts to

Common stock

2K shares

−2K

Strike price

Held after

0.00

Exercisable

—

3/2/2026

Restricted stock units

Direct

M · Option Exercise

Converts to

Common stock

5.67K shares

−5.67K

Strike price

Held after

5.67K

Exercisable

—

3/2/2026

Restricted stock units

Direct

M · Option Exercise

Converts to

Common stock

4K shares

−4K

Strike price

Held after

Exercisable

—

3/2/2026

Restricted stock units

Direct

M · Option Exercise

Converts to

Common stock

5.30K shares

−5.30K

Strike price

Held after

10.61K

Exercisable

—

3/2/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Restricted stock units Direct	Common stock14K shares	3/1/2026	A · Award	+14K		—	14K
Stock options (right to buy) Direct	Common stock52K shares	3/1/2026	A · Award	+52K	30.23	—	52K
Restricted stock units Direct	Common stock2K shares	3/2/2026	M · Option Exercise	−2K		—	0.00
Restricted stock units Direct	Common stock5.67K shares	3/2/2026	M · Option Exercise	−5.67K		—	5.67K
Restricted stock units Direct	Common stock4K shares	3/2/2026	M · Option Exercise	−4K		—	8K
Restricted stock units Direct	Common stock5.30K shares	3/2/2026	M · Option Exercise	−5.30K		—	10.61K