Filed: 2/17/2026ACC: 0002111609-26-000001
📋 What this filing means
ISHARA INVESTMENTS LP filed this quarterly 13F‑HR report disclosing 38 equity positions with a total reported market value of $87.46M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
38
Positions
$87.46M
Total AUM (reported)
6.81M
Total Shares
Allocation by class
COM$59.83M68.4%
COM NEW$15.73M18.0%
COM CL A$3.58M4.1%
SPONSORED ADS$2.16M2.5%
COM PAR $.01$1.74M2.0%
ADS$1.46M1.7%
SPONSORED ADR$1.07M1.2%
Portfolio Concentration
Top 3$24.01M27.5%
4–10$24.92M28.5%
11–25$26.74M30.6%
Rest$11.78M13.5%
Top 3 weight
27.5%
Top 10 weight
55.9%
Voting Authority Distribution
Total shares with voting rights: 6.76M
Sole
Full voting authority
6.76M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole38
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings38
Rows:
PRAXIS PRECISION MEDICINES I
SOLEShares40K
TypeSH
Market value$11.79M
13.48%
Sole
40K
Shared
0.00
None
0.00
XERIS BIOPHARMA HOLDINGS INC
SOLEShares800K
TypeSH
Market value$6.28M
7.18%
Sole
800K
Shared
0.00
None
0.00
BIOMARIN PHARMACEUTICAL INC
SOLEShares100K
TypeSH
Market value$5.94M
6.80%
Sole
100K
Shared
0.00
None
0.00
AMICUS THERAPEUTICS INC
SOLEShares360K
TypeSH
Market value$5.13M
5.86%
Sole
360K
Shared
0.00
None
0.00
ACADIA PHARMACEUTICALS INC
SOLEShares160K
TypeSH
Market value$4.27M
4.89%
Sole
160K
Shared
0.00
None
0.00
ANNEXON INC
SOLEShares750K
TypeSH
Market value$3.77M
4.31%
Sole
750K
Shared
0.00
None
0.00
NUVATION BIO INC
SOLEShares400K
TypeSH
Market value$3.58M
4.10%
Sole
400K
Shared
0.00
None
0.00
BRIDGEBIO PHARMA INC
SOLEShares36K
TypeSH
Market value$2.75M
3.15%
Sole
36K
Shared
0.00
None
0.00
PTC THERAPEUTICS INC
SOLEShares36K
TypeSH
Market value$2.73M
3.13%
Sole
36K
Shared
0.00
None
0.00
UNITED THERAPEUTICS CORP DEL
SOLEShares5.50K
TypeSH
Market value$2.68M
3.06%
Sole
5.50K
Shared
0.00
None
0.00
BIOCRYST PHARMACEUTICALS INC
SOLEShares300K
TypeSH
Market value$2.34M
2.68%
Sole
300K
Shared
0.00
None
0.00
VAXCYTE INC
SOLEShares50K
TypeSH
Market value$2.31M
2.64%
Sole
50K
Shared
0.00
None
0.00
GENMAB A/S
SOLEShares70K
TypeSH
Market value$2.16M
2.47%
Sole
70K
Shared
0.00
None
0.00
SYNDAX PHARMACEUTICALS INC
SOLEShares100K
TypeSH
Market value$2.10M
2.40%
Sole
100K
Shared
0.00
None
0.00
VERASTEM INC
SOLEShares270K
TypeSH
Market value$2.08M
2.38%
Sole
270K
Shared
0.00
None
0.00
TARSUS PHARMACEUTICALS INC
SOLEShares24K
TypeSH
Market value$1.97M
2.25%
Sole
24K
Shared
0.00
None
0.00
APOGEE ENTERPRISES INC
SOLEShares25K
TypeSH
Market value$1.89M
2.16%
Sole
25K
Shared
0.00
None
0.00
ZENTALIS PHARMACEUTICALS INC
SOLEShares1.32M
TypeSH
Market value$1.78M
2.04%
Sole
1.32M
Shared
0.00
None
0.00
INSMED INC
SOLEShares10K
TypeSH
Market value$1.74M
1.99%
Sole
10K
Shared
0.00
None
0.00
CORCEPT THERAPEUTICS INC
SOLEShares44K
TypeSH
Market value$1.53M
1.75%
Sole
0.00
Shared
0.00
None
0.00
SILENCE THERAPEUTICS PLC
SOLEShares240K
TypeSH
Market value$1.46M
1.67%
Sole
240K
Shared
0.00
None
0.00
EDGEWISE THERAPEUTICS INC
SOLEShares58K
TypeSH
Market value$1.44M
1.65%
Sole
58K
Shared
0.00
None
0.00
BEAM THERAPEUTICS INC
SOLEShares50K
TypeSH
Market value$1.39M
1.58%
Sole
50K
Shared
0.00
None
0.00
ORIC PHARMACEUTICALS INC
SOLEShares160K
TypeSH
Market value$1.31M
1.50%
Sole
160K
Shared
0.00
None
0.00
APELLIS PHARMACEUTICALS INC
SOLEShares50K
TypeSH
Market value$1.26M
1.44%
Sole
50K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
PRAXIS PRECISION MEDICINES ISOLE | COM NEW | 40K | SH | $11.79M 13.48% | 40K | 0.00 | 0.00 |
XERIS BIOPHARMA HOLDINGS INCSOLE | COM | 800K | SH | $6.28M 7.18% | 800K | 0.00 | 0.00 |
BIOMARIN PHARMACEUTICAL INCSOLE | COM | 100K | SH | $5.94M 6.80% | 100K | 0.00 | 0.00 |
AMICUS THERAPEUTICS INCSOLE | COM | 360K | SH | $5.13M 5.86% | 360K | 0.00 | 0.00 |
ACADIA PHARMACEUTICALS INCSOLE | COM | 160K | SH | $4.27M 4.89% | 160K | 0.00 | 0.00 |
ANNEXON INCSOLE | COM | 750K | SH | $3.77M 4.31% | 750K | 0.00 | 0.00 |
NUVATION BIO INCSOLE | COM CL A | 400K | SH | $3.58M 4.10% | 400K | 0.00 | 0.00 |
BRIDGEBIO PHARMA INCSOLE | COM | 36K | SH | $2.75M 3.15% | 36K | 0.00 | 0.00 |
PTC THERAPEUTICS INCSOLE | COM | 36K | SH | $2.73M 3.13% | 36K | 0.00 | 0.00 |
UNITED THERAPEUTICS CORP DELSOLE | COM | 5.50K | SH | $2.68M 3.06% | 5.50K | 0.00 | 0.00 |
BIOCRYST PHARMACEUTICALS INCSOLE | COM | 300K | SH | $2.34M 2.68% | 300K | 0.00 | 0.00 |
VAXCYTE INCSOLE | COM | 50K | SH | $2.31M 2.64% | 50K | 0.00 | 0.00 |
GENMAB A/SSOLE | SPONSORED ADS | 70K | SH | $2.16M 2.47% | 70K | 0.00 | 0.00 |
SYNDAX PHARMACEUTICALS INCSOLE | COM | 100K | SH | $2.10M 2.40% | 100K | 0.00 | 0.00 |
VERASTEM INCSOLE | COM NEW | 270K | SH | $2.08M 2.38% | 270K | 0.00 | 0.00 |
TARSUS PHARMACEUTICALS INCSOLE | COM | 24K | SH | $1.97M 2.25% | 24K | 0.00 | 0.00 |
APOGEE ENTERPRISES INCSOLE | COM | 25K | SH | $1.89M 2.16% | 25K | 0.00 | 0.00 |
ZENTALIS PHARMACEUTICALS INCSOLE | COM | 1.32M | SH | $1.78M 2.04% | 1.32M | 0.00 | 0.00 |
INSMED INCSOLE | COM PAR $.01 | 10K | SH | $1.74M 1.99% | 10K | 0.00 | 0.00 |
CORCEPT THERAPEUTICS INCSOLE | COM | 44K | SH | $1.53M 1.75% | 0.00 | 0.00 | 0.00 |
SILENCE THERAPEUTICS PLCSOLE | ADS | 240K | SH | $1.46M 1.67% | 240K | 0.00 | 0.00 |
EDGEWISE THERAPEUTICS INCSOLE | COM | 58K | SH | $1.44M 1.65% | 58K | 0.00 | 0.00 |
BEAM THERAPEUTICS INCSOLE | COM | 50K | SH | $1.39M 1.58% | 50K | 0.00 | 0.00 |
ORIC PHARMACEUTICALS INCSOLE | COM | 160K | SH | $1.31M 1.50% | 160K | 0.00 | 0.00 |
APELLIS PHARMACEUTICALS INCSOLE | COM | 50K | SH | $1.26M 1.44% | 50K | 0.00 | 0.00 |
Page 1 of 2