Filed: 8/14/2025ACC: 0001420506-25-002181
📋 What this filing means
IKARIAN CAPITAL, LLC filed this quarterly 13F‑HR report disclosing 114 equity positions with a total reported market value of $520.63M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
114
Positions
$520.63M
Total AUM (reported)
42.24M
Total Shares
Allocation by class
COM$283.06M54.4%
COM NEW$146.62M28.2%
SPONSORED ADS$24.11M4.6%
COM PAR $.01$16.48M3.2%
CALL$15.38M3.0%
CLASS A ORD$13.64M2.6%
SHS USD$4.24M0.8%
Portfolio Concentration
Top 3$127.59M24.5%
4–10$119.10M22.9%
11–25$144.97M27.8%
Rest$128.97M24.8%
Top 3 weight
24.5%
Top 10 weight
47.4%
Voting Authority Distribution
Total shares with voting rights: 42.24M
Sole
Full voting authority
42.24M
shares
% of voting shares100.0%
Shared
Joint voting authority
0.00
shares
% of voting shares0.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole114
Shared0
Other0
Dominant voting typeSole · 100.0% of voting shares
Institutional Holdings114
Rows:
CIDARA THERAPEUTICS INC
SOLEShares1.29M
TypeSH
Market value$62.69M
12.04%
Sole
1.29M
Shared
0.00
None
0.00
SOLENO THERAPEUTICS INC
SOLEShares400K
TypeSH
Market value$33.51M
6.44%
Sole
400K
Shared
0.00
None
0.00
ULTRAGENYX PHARMACEUTICAL IN
SOLEShares863.10K
TypeSH
Market value$31.38M
6.03%
Sole
863.10K
Shared
0.00
None
0.00
PRAXIS PRECISION MEDICINES I
SOLEShares519.35K
TypeSH
Market value$21.84M
4.19%
Sole
519.35K
Shared
0.00
None
0.00
CAPRICOR THERAPEUTICS INC
SOLEShares2.06M
TypeSH
Market value$20.46M
3.93%
Sole
2.06M
Shared
0.00
None
0.00
ALNYLAM PHARMACEUTICALS INC
SOLEShares56.59K
TypeSH
Market value$18.45M
3.54%
Sole
56.59K
Shared
0.00
None
0.00
INSMED INC
SOLEShares163.75K
TypeSH
Market value$16.48M
3.17%
Sole
163.75K
Shared
0.00
None
0.00
AKERO THERAPEUTICS INC
SOLEShares264.40K
TypeSH
Market value$14.11M
2.71%
Sole
264.40K
Shared
0.00
None
0.00
VERONA PHARMA PLC
SOLEShares146.83K
TypeSH
Market value$13.89M
2.67%
Sole
146.83K
Shared
0.00
None
0.00
APOGEE THERAPEUTICS INC
SOLEShares319.55K
TypeSH
Market value$13.88M
2.67%
Sole
319.55K
Shared
0.00
None
0.00
MOONLAKE IMMUNOTHERAPEUTICS
SOLEShares289K
TypeSH
Market value$13.64M
2.62%
Sole
289K
Shared
0.00
None
0.00
SAREPTA THERAPEUTICS INC
SOLEShares781.19K
TypeSH
Market value$13.36M
2.57%
Sole
781.19K
Shared
0.00
None
0.00
CYTOKINETICS INC
SOLEShares383.46K
TypeSH
Market value$12.67M
2.43%
Sole
383.46K
Shared
0.00
None
0.00
CRINETICS PHARMACEUTICALS IN
SOLEShares433.43K
TypeSH
Market value$12.47M
2.39%
Sole
433.43K
Shared
0.00
None
0.00
VIKING THERAPEUTICS INC
SOLEShares450K
TypeSH
Market value$11.93M
2.29%
Sole
450K
Shared
0.00
None
0.00
UNIQURE NV
SOLEShares800K
TypeSH
Market value$11.15M
2.14%
Sole
800K
Shared
0.00
None
0.00
VAXCYTE INC
SOLEShares311.90K
TypeSH
Market value$10.14M
1.95%
Sole
311.90K
Shared
0.00
None
0.00
COGENT BIOSCIENCES INC
SOLEShares1.30M
TypeSH
Market value$9.32M
1.79%
Sole
1.30M
Shared
0.00
None
0.00
ALPHA COGNITION INC
SOLEShares917.87K
TypeSH
Market value$8.56M
1.64%
Sole
917.87K
Shared
0.00
None
0.00
TARSUS PHARMACEUTICALS INC
SOLEShares196.54K
TypeSH
Market value$7.96M
1.53%
Sole
196.54K
Shared
0.00
None
0.00
TG THERAPEUTICS INC
SOLEShares209.94K
TypeSH
Market value$7.56M
1.45%
Sole
209.94K
Shared
0.00
None
0.00
KALVISTA PHARMACEUTICALS INC
SOLEShares598.53K
TypeSH
Market value$6.77M
1.30%
Sole
598.53K
Shared
0.00
None
0.00
FULCRUM THERAPEUTICS INC
SOLEShares962.52K
TypeSH
Market value$6.62M
1.27%
Sole
962.52K
Shared
0.00
None
0.00
VIRIDIAN THERAPEUTICS INC
SOLEShares469.95K
TypeSH
Market value$6.57M
1.26%
Sole
469.95K
Shared
0.00
None
0.00
ARVINAS INC
SOLEShares850K
TypeSH
Market value$6.26M
1.20%
Sole
850K
Shared
0.00
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
CIDARA THERAPEUTICS INCSOLE | COM NEW | 1.29M | SH | $62.69M 12.04% | 1.29M | 0.00 | 0.00 |
SOLENO THERAPEUTICS INCSOLE | COM | 400K | SH | $33.51M 6.44% | 400K | 0.00 | 0.00 |
ULTRAGENYX PHARMACEUTICAL INSOLE | COM | 863.10K | SH | $31.38M 6.03% | 863.10K | 0.00 | 0.00 |
PRAXIS PRECISION MEDICINES ISOLE | COM NEW | 519.35K | SH | $21.84M 4.19% | 519.35K | 0.00 | 0.00 |
CAPRICOR THERAPEUTICS INCSOLE | COM NEW | 2.06M | SH | $20.46M 3.93% | 2.06M | 0.00 | 0.00 |
ALNYLAM PHARMACEUTICALS INCSOLE | COM | 56.59K | SH | $18.45M 3.54% | 56.59K | 0.00 | 0.00 |
INSMED INCSOLE | COM PAR $.01 | 163.75K | SH | $16.48M 3.17% | 163.75K | 0.00 | 0.00 |
AKERO THERAPEUTICS INCSOLE | COM | 264.40K | SH | $14.11M 2.71% | 264.40K | 0.00 | 0.00 |
VERONA PHARMA PLCSOLE | SPONSORED ADS | 146.83K | SH | $13.89M 2.67% | 146.83K | 0.00 | 0.00 |
APOGEE THERAPEUTICS INCSOLE | COM | 319.55K | SH | $13.88M 2.67% | 319.55K | 0.00 | 0.00 |
MOONLAKE IMMUNOTHERAPEUTICSSOLE | CLASS A ORD | 289K | SH | $13.64M 2.62% | 289K | 0.00 | 0.00 |
SAREPTA THERAPEUTICS INCSOLE | COM | 781.19K | SH | $13.36M 2.57% | 781.19K | 0.00 | 0.00 |
CYTOKINETICS INCSOLE | COM NEW | 383.46K | SH | $12.67M 2.43% | 383.46K | 0.00 | 0.00 |
CRINETICS PHARMACEUTICALS INSOLE | COM | 433.43K | SH | $12.47M 2.39% | 433.43K | 0.00 | 0.00 |
VIKING THERAPEUTICS INCSOLE | COM | 450K | SH | $11.93M 2.29% | 450K | 0.00 | 0.00 |
UNIQURE NVSOLE | CALL | 800K | SH | $11.15M 2.14% | 800K | 0.00 | 0.00 |
VAXCYTE INCSOLE | COM | 311.90K | SH | $10.14M 1.95% | 311.90K | 0.00 | 0.00 |
COGENT BIOSCIENCES INCSOLE | COM | 1.30M | SH | $9.32M 1.79% | 1.30M | 0.00 | 0.00 |
ALPHA COGNITION INCSOLE | COM NEW | 917.87K | SH | $8.56M 1.64% | 917.87K | 0.00 | 0.00 |
TARSUS PHARMACEUTICALS INCSOLE | COM | 196.54K | SH | $7.96M 1.53% | 196.54K | 0.00 | 0.00 |
TG THERAPEUTICS INCSOLE | COM | 209.94K | SH | $7.56M 1.45% | 209.94K | 0.00 | 0.00 |
KALVISTA PHARMACEUTICALS INCSOLE | COM | 598.53K | SH | $6.77M 1.30% | 598.53K | 0.00 | 0.00 |
FULCRUM THERAPEUTICS INCSOLE | COM | 962.52K | SH | $6.62M 1.27% | 962.52K | 0.00 | 0.00 |
VIRIDIAN THERAPEUTICS INCSOLE | COM | 469.95K | SH | $6.57M 1.26% | 469.95K | 0.00 | 0.00 |
ARVINAS INCSOLE | COM | 850K | SH | $6.26M 1.20% | 850K | 0.00 | 0.00 |
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