HORN MARGARET A (See Remarks) sold 37.7% of their position (93.58K shares) of REVOLUTION MEDICINES, INC. on the open market

Open‑market sale worth $14.97M — a major position exit. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 3 sales

HORN MARGARET A

Filed: 6/17/2026ACC: 0001610717-26-000230

InsiderHORN MARGARET ACIK 1294192

→

IssuerREVOLUTION MEDICINES, INC.CIK 1628171

Officer· See Remarks

Since Feb 2020

-93.58K

Net shares

Net seller

$14.97M

Total sold

Open market trades

0B · 3S

Total transactions

90K acquired · 183.57K disposed

Non-Derivative Transactions8

Common Stock

Direct

S · Sale

−3.58K

Price / share

$156.12

Trade value

$558.13K

% of position

2.3%

6/16/2025

158.22K→154.65K

Common Stock

Direct

M · Option Exercise

+15.55K

Price / share

$40.74

Trade value

$633.34K

% of position

9.8%

6/15/2026

158.22K→173.77K

Common Stock

Direct

M · Option Exercise

+44.85K

Price / share

$29.80

Trade value

$1.34M

% of position

25.8%

6/15/2026

173.77K→218.62K

Common Stock

Direct

S · Sale

−60.40K

Price / share

$160.17

Trade value

$9.67M

% of position

27.6%

6/15/2026

218.62K→158.22K

Common Stock

Direct

M · Option Exercise

+573.00

Price / share

$40.74

Trade value

$23.34K

% of position

0.4%

6/17/2026

154.65K→155.22K

Common Stock

Direct

M · Option Exercise

+3.30K

Price / share

$29.80

Trade value

$98.40K

% of position

2.1%

6/17/2026

155.22K→158.52K

Common Stock

Direct

M · Option Exercise

+25.73K

Price / share

$26.50

Trade value

$681.71K

% of position

16.2%

6/17/2026

158.52K→184.25K

Common Stock

Direct

S · Sale

−29.60K

Price / share

$160.12

Trade value

$4.74M

% of position

16.1%

6/17/2026

184.25K→154.65K

Total

Net shares

−3.58K

Net value

-$12.20M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	6/16/2025	S · Sale	−3.58K	$156.12	$558.13K	2.3%	158.22K	154.65K
Common Stock Direct	6/15/2026	M · Option Exercise	+15.55K	$40.74	$633.34K	9.8%	158.22K	173.77K
Common Stock Direct	6/15/2026	M · Option Exercise	+44.85K	$29.80	$1.34M	25.8%	173.77K	218.62K
Common Stock Direct	6/15/2026	S · Sale	−60.40K	$160.17	$9.67M	27.6%	218.62K	158.22K
Common Stock Direct	6/17/2026	M · Option Exercise	+573.00	$40.74	$23.34K	0.4%	154.65K	155.22K
Common Stock Direct	6/17/2026	M · Option Exercise	+3.30K	$29.80	$98.40K	2.1%	155.22K	158.52K
Common Stock Direct	6/17/2026	M · Option Exercise	+25.73K	$26.50	$681.71K	16.2%	158.52K	184.25K
Common Stock Direct	6/17/2026	S · Sale	−29.60K	$160.12	$4.74M	16.1%	184.25K	154.65K
Total			−3.58K		-$12.20M

Derivative Transactions5

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

15.55K shares

−15.55K

Strike price

40.74

Held after

75.65K

Exercisable

—

6/15/2026

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

44.85K shares

−44.85K

Strike price

29.8

Held after

75.05K

Exercisable

—

6/15/2026

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

573.00 shares

−573.00

Strike price

40.74

Held after

75.08K

Exercisable

—

6/17/2026

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.30K shares

−3.30K

Strike price

29.8

Held after

71.75K

Exercisable

—

6/17/2026

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

25.73K shares

−25.73K

Strike price

26.5

Held after

114.28K

Exercisable

—

6/17/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Stock Option (Right to Buy) Direct	Common Stock15.55K shares	6/15/2026	M · Option Exercise	−15.55K	40.74	—	75.65K
Stock Option (Right to Buy) Direct	Common Stock44.85K shares	6/15/2026	M · Option Exercise	−44.85K	29.8	—	75.05K
Stock Option (Right to Buy) Direct	Common Stock573.00 shares	6/17/2026	M · Option Exercise	−573.00	40.74	—	75.08K
Stock Option (Right to Buy) Direct	Common Stock3.30K shares	6/17/2026	M · Option Exercise	−3.30K	29.8	—	71.75K
Stock Option (Right to Buy) Direct	Common Stock25.73K shares	6/17/2026	M · Option Exercise	−25.73K	26.5	—	114.28K