HORN MARGARET A (See Remarks) sold 5.9% of their position (10K shares) of REVOLUTION MEDICINES, INC. on the open market

Open‑market sale worth $1.48M — a moderate reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 7 sales

HORN MARGARET A

Filed: 6/15/2026ACC: 0001610717-26-000216

InsiderHORN MARGARET ACIK 1294192

→

IssuerREVOLUTION MEDICINES, INC.CIK 1628171

Officer· See Remarks

Since Feb 2020

-10K

Net shares

Net seller

$1.48M

Total sold

Open market trades

0B · 7S

Total transactions

10K acquired · 20K disposed

Non-Derivative Transactions9

Common Stock

Direct

M · Option Exercise

+1.09K

Price / share

$42.45

Trade value

$46.44K

% of position

0.7%

6/11/2026

158.22K→159.32K

Common Stock

Direct

M · Option Exercise

+8.91K

Price / share

$40.74

Trade value

$362.83K

% of position

5.6%

6/11/2026

159.32K→168.22K

Common Stock

Direct

S · Sale

−1.31K

Price / share

$144.28

Trade value

$189.73K

% of position

0.8%

6/11/2026

168.22K→166.91K

Common Stock

Direct

S · Sale

−885.00

Price / share

$145.15

Trade value

$128.46K

% of position

0.5%

6/11/2026

166.91K→166.02K

Common Stock

Direct

S · Sale

−700.00

Price / share

$146.04

Trade value

$102.23K

% of position

0.4%

6/11/2026

166.02K→165.32K

Common Stock

Direct

S · Sale

−500.00

Price / share

$147.27

Trade value

$73.64K

% of position

0.3%

6/11/2026

165.32K→164.82K

Common Stock

Direct

S · Sale

−1.80K

Price / share

$148.72

Trade value

$267.70K

% of position

1.1%

6/11/2026

164.82K→163.02K

Common Stock

Direct

S · Sale

−4.60K

Price / share

$149.64

Trade value

$688.36K

% of position

2.8%

6/11/2026

163.02K→158.42K

Common Stock

Direct

S · Sale

−200.00

Price / share

$150.17

Trade value

$30.03K

% of position

0.1%

6/11/2026

158.42K→158.22K

Total

Net shares

+0.00

Net value

-$1.07M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	6/11/2026	M · Option Exercise	+1.09K	$42.45	$46.44K	0.7%	158.22K	159.32K
Common Stock Direct	6/11/2026	M · Option Exercise	+8.91K	$40.74	$362.83K	5.6%	159.32K	168.22K
Common Stock Direct	6/11/2026	S · Sale	−1.31K	$144.28	$189.73K	0.8%	168.22K	166.91K
Common Stock Direct	6/11/2026	S · Sale	−885.00	$145.15	$128.46K	0.5%	166.91K	166.02K
Common Stock Direct	6/11/2026	S · Sale	−700.00	$146.04	$102.23K	0.4%	166.02K	165.32K
Common Stock Direct	6/11/2026	S · Sale	−500.00	$147.27	$73.64K	0.3%	165.32K	164.82K
Common Stock Direct	6/11/2026	S · Sale	−1.80K	$148.72	$267.70K	1.1%	164.82K	163.02K
Common Stock Direct	6/11/2026	S · Sale	−4.60K	$149.64	$688.36K	2.8%	163.02K	158.42K
Common Stock Direct	6/11/2026	S · Sale	−200.00	$150.17	$30.03K	0.1%	158.42K	158.22K
Total			+0.00		-$1.07M

Derivative Transactions2

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

1.09K shares

−1.09K

Strike price

42.45

Held after

0.00

Exercisable

—

6/11/2026

Stock Option (Right to Buy)

Direct

M · Option Exercise

Converts to

Common Stock

8.91K shares

−8.91K

Strike price

40.74

Held after

91.19K

Exercisable

—

6/11/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Stock Option (Right to Buy) Direct	Common Stock1.09K shares	6/11/2026	M · Option Exercise	−1.09K	42.45	—	0.00
Stock Option (Right to Buy) Direct	Common Stock8.91K shares	6/11/2026	M · Option Exercise	−8.91K	40.74	—	91.19K