HIRANO PATRICIA C (See Remarks) sold 83.5% of their position (156.31K shares) of SOLENO THERAPEUTICS INC on the open market

Open‑market sale worth $10.71M — a major position exit. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 16 sales

HIRANO PATRICIA C

Filed: 3/31/2025ACC: 0001415889-25-009291

InsiderHIRANO PATRICIA CCIK 1766042

→

IssuerSOLENO THERAPEUTICS INCCIK 1484565

Officer· See Remarks

Since Jan 2019

-156.31K

Net shares

Net seller

$10.71M

Total sold

Open market trades

0B · 16S

Total transactions

74.83K acquired · 231.15K disposed

Non-Derivative Transactions23

Common Stock

Direct

S · Sale

−1.42K

Price / share

$65.97

Trade value

$93.54K

% of position

1.3%

3/27/2025

112.30K→110.88K

Common Stock

Direct

S · Sale

−2.31K

Price / share

$66.79

Trade value

$154.29K

% of position

2.1%

3/27/2025

110.88K→108.57K

Common Stock

Direct

S · Sale

−4.20K

Price / share

$67.70

Trade value

$284.28K

% of position

3.9%

3/27/2025

108.57K→104.38K

Common Stock

Direct

S · Sale

−5.52K

Price / share

$68.79

Trade value

$379.99K

% of position

5.3%

3/27/2025

104.38K→98.85K

Common Stock

Direct

S · Sale

−3.20K

Price / share

$69.84

Trade value

$223.34K

% of position

3.2%

3/27/2025

98.85K→95.65K

Common Stock

Direct

S · Sale

−329.00

Price / share

$70.73

Trade value

$23.27K

% of position

0.3%

3/27/2025

95.65K→95.32K

Common Stock

Direct

S · Sale

−478.00

Price / share

$71.74

Trade value

$34.29K

% of position

0.5%

3/27/2025

95.32K→94.85K

Common Stock

Direct

S · Sale

−73.00

Price / share

$72.64

Trade value

$5.30K

% of position

0.1%

3/27/2025

94.85K→94.77K

Common Stock

Direct

M · Option Exercise

+6K

Price / share

$24.00

Trade value

$144K

% of position

6.3%

3/27/2025

94.77K→100.77K

Common Stock

Direct

M · Option Exercise

+4.40K

Price / share

$25.05

Trade value

$110.22K

% of position

4.4%

3/27/2025

100.77K→105.17K

Common Stock

Direct

M · Option Exercise

+4.89K

Price / share

$5.10

Trade value

$24.93K

% of position

4.6%

3/27/2025

105.17K→110.06K

Common Stock

Direct

M · Option Exercise

+13.33K

Price / share

$2.60

Trade value

$34.60K

% of position

12.1%

3/27/2025

110.06K→123.39K

Common Stock

Direct

M · Option Exercise

+8.33K

Price / share

$2.41

Trade value

$20.08K

% of position

6.8%

3/27/2025

123.39K→131.73K

Common Stock

Direct

M · Option Exercise

+35.19K

Price / share

$5.25

Trade value

$184.73K

% of position

26.7%

3/27/2025

131.73K→166.91K

Common Stock

Direct

S · Sale

−46.21K

Price / share

$66.39

Trade value

$3.07M

% of position

27.7%

3/27/2025

166.91K→120.70K

Common Stock

Direct

S · Sale

−24.78K

Price / share

$67.47

Trade value

$1.67M

% of position

20.5%

3/27/2025

120.70K→95.92K

Common Stock

Direct

S · Sale

−24.99K

Price / share

$70.18

Trade value

$1.75M

% of position

26.1%

3/27/2025

95.92K→70.93K

Common Stock

Direct

S · Sale

−15.14K

Price / share

$72.50

Trade value

$1.10M

% of position

21.4%

3/27/2025

70.93K→55.79K

Common Stock

Direct

M · Option Exercise

+2.69K

Price / share

$33.60

Trade value

$90.42K

% of position

4.8%

3/28/2025

55.79K→58.48K

Common Stock

Direct

S · Sale

−3.39K

Price / share

$67.46

Trade value

$228.95K

% of position

5.8%

3/28/2025

58.48K→55.09K

Common Stock

Direct

S · Sale

−12.32K

Price / share

$68.92

Trade value

$849.39K

% of position

22.4%

3/28/2025

55.09K→42.76K

Common Stock

Direct

S · Sale

−9.25K

Price / share

$69.52

Trade value

$643.25K

% of position

21.6%

3/28/2025

42.76K→33.51K

Common Stock

Direct

S · Sale

−2.69K

Price / share

$73.60

Trade value

$198.06K

% of position

8.0%

3/28/2025

33.51K→30.82K

Total

Net shares

−81.48K

Net value

-$10.10M

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	3/27/2025	S · Sale	−1.42K	$65.97	$93.54K	1.3%	112.30K	110.88K
Common Stock Direct	3/27/2025	S · Sale	−2.31K	$66.79	$154.29K	2.1%	110.88K	108.57K
Common Stock Direct	3/27/2025	S · Sale	−4.20K	$67.70	$284.28K	3.9%	108.57K	104.38K
Common Stock Direct	3/27/2025	S · Sale	−5.52K	$68.79	$379.99K	5.3%	104.38K	98.85K
Common Stock Direct	3/27/2025	S · Sale	−3.20K	$69.84	$223.34K	3.2%	98.85K	95.65K
Common Stock Direct	3/27/2025	S · Sale	−329.00	$70.73	$23.27K	0.3%	95.65K	95.32K
Common Stock Direct	3/27/2025	S · Sale	−478.00	$71.74	$34.29K	0.5%	95.32K	94.85K
Common Stock Direct	3/27/2025	S · Sale	−73.00	$72.64	$5.30K	0.1%	94.85K	94.77K
Common Stock Direct	3/27/2025	M · Option Exercise	+6K	$24.00	$144K	6.3%	94.77K	100.77K
Common Stock Direct	3/27/2025	M · Option Exercise	+4.40K	$25.05	$110.22K	4.4%	100.77K	105.17K
Common Stock Direct	3/27/2025	M · Option Exercise	+4.89K	$5.10	$24.93K	4.6%	105.17K	110.06K
Common Stock Direct	3/27/2025	M · Option Exercise	+13.33K	$2.60	$34.60K	12.1%	110.06K	123.39K
Common Stock Direct	3/27/2025	M · Option Exercise	+8.33K	$2.41	$20.08K	6.8%	123.39K	131.73K
Common Stock Direct	3/27/2025	M · Option Exercise	+35.19K	$5.25	$184.73K	26.7%	131.73K	166.91K
Common Stock Direct	3/27/2025	S · Sale	−46.21K	$66.39	$3.07M	27.7%	166.91K	120.70K
Common Stock Direct	3/27/2025	S · Sale	−24.78K	$67.47	$1.67M	20.5%	120.70K	95.92K
Common Stock Direct	3/27/2025	S · Sale	−24.99K	$70.18	$1.75M	26.1%	95.92K	70.93K
Common Stock Direct	3/27/2025	S · Sale	−15.14K	$72.50	$1.10M	21.4%	70.93K	55.79K
Common Stock Direct	3/28/2025	M · Option Exercise	+2.69K	$33.60	$90.42K	4.8%	55.79K	58.48K
Common Stock Direct	3/28/2025	S · Sale	−3.39K	$67.46	$228.95K	5.8%	58.48K	55.09K
Common Stock Direct	3/28/2025	S · Sale	−12.32K	$68.92	$849.39K	22.4%	55.09K	42.76K
Common Stock Direct	3/28/2025	S · Sale	−9.25K	$69.52	$643.25K	21.6%	42.76K	33.51K
Common Stock Direct	3/28/2025	S · Sale	−2.69K	$73.60	$198.06K	8.0%	33.51K	30.82K
Total			−81.48K		-$10.10M

Derivative Transactions7

Employee stock option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

6K shares

−6K

Strike price

Held after

0.00

Exercisable

—

3/27/2025

Employee stock option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

4.40K shares

−4.40K

Strike price

25.05

Held after

0.00

Exercisable

—

3/27/2025

Employee stock option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

4.89K shares

−4.89K

Strike price

5.10

Held after

2.44K

Exercisable

—

3/27/2025

Employee stock option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

13.33K shares

−13.33K

Strike price

2.595

Held after

0.00

Exercisable

—

3/27/2025

Employee stock option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

8.33K shares

−8.33K

Strike price

2.41

Held after

11.67K

Exercisable

—

3/27/2025

Employee stock option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

35.19K shares

−35.19K

Strike price

5.25

Held after

49.26K

Exercisable

—

3/27/2025

Employee stock option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

2.69K shares

−2.69K

Strike price

33.60

Held after

18.84K

Exercisable

—

3/28/2025

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Employee stock option (right to buy) Direct	Common Stock6K shares	3/27/2025	M · Option Exercise	−6K	24	—	0.00
Employee stock option (right to buy) Direct	Common Stock4.40K shares	3/27/2025	M · Option Exercise	−4.40K	25.05	—	0.00
Employee stock option (right to buy) Direct	Common Stock4.89K shares	3/27/2025	M · Option Exercise	−4.89K	5.10	—	2.44K
Employee stock option (right to buy) Direct	Common Stock13.33K shares	3/27/2025	M · Option Exercise	−13.33K	2.595	—	0.00
Employee stock option (right to buy) Direct	Common Stock8.33K shares	3/27/2025	M · Option Exercise	−8.33K	2.41	—	11.67K
Employee stock option (right to buy) Direct	Common Stock35.19K shares	3/27/2025	M · Option Exercise	−35.19K	5.25	—	49.26K
Employee stock option (right to buy) Direct	Common Stock2.69K shares	3/28/2025	M · Option Exercise	−2.69K	33.60	—	18.84K