GRIFFITHS RICHARD IAN

PrivateCIK: 1846370

GRIFFITHS RICHARD IAN

Filed: 8/13/2026ACC: 0001104659-26-095574

InsiderGRIFFITHS RICHARD IANCIK 1846370

→

IssuerSILENCE THERAPEUTICS PLCCIK 1479615

10% Owner

Since Aug 2025

+5.48M

Net shares

Net buyer

$0.00

Total acquired

0

Open market trades

0B · 0S

11

Total transactions

5.48M acquired

Non-Derivative Transactions0

No non-derivative transactions reported

Derivative Transactions11

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

8.38M shares

Shares

+2.79M

Strike price

16.00

Held after

7.49M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

300K shares

Shares

+100K

Strike price

15.58

Held after

7.39M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

150K shares

Shares

+50K

Strike price

16.09

Held after

7.34M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

10.50K shares

Shares

+3.50K

Strike price

16.35

Held after

7.34M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

2.40M shares

Shares

+800K

Strike price

16.00

Held after

6.54M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

1.15M shares

Shares

+382K

Strike price

16.00

Held after

6.15M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

1.41M shares

Shares

+470.82K

Strike price

16.09

Held after

5.68M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

1.82M shares

Shares

+605.17K

Strike price

16.00

Held after

5.08M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

360K shares

Shares

+120K

Strike price

16.00

Held after

4.96M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

180K shares

Shares

+60K

Strike price

16.35

Held after

4.90M

Exercisable

—

8/10/2026

American Depositary Shares

Indirect

S · Sale

Converts to

Ordinary Shares

300K shares

Shares

+100K

Strike price

16.00

Held after

4.80M

Exercisable

—

8/10/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
American Depositary Shares Indirect	Ordinary Shares8.38M shares	8/10/2026	S · Sale	+2.79M	16.00	—	7.49M
American Depositary Shares Indirect	Ordinary Shares300K shares	8/10/2026	S · Sale	+100K	15.58	—	7.39M
American Depositary Shares Indirect	Ordinary Shares150K shares	8/10/2026	S · Sale	+50K	16.09	—	7.34M
American Depositary Shares Indirect	Ordinary Shares10.50K shares	8/10/2026	S · Sale	+3.50K	16.35	—	7.34M
American Depositary Shares Indirect	Ordinary Shares2.40M shares	8/10/2026	S · Sale	+800K	16.00	—	6.54M
American Depositary Shares Indirect	Ordinary Shares1.15M shares	8/10/2026	S · Sale	+382K	16.00	—	6.15M
American Depositary Shares Indirect	Ordinary Shares1.41M shares	8/10/2026	S · Sale	+470.82K	16.09	—	5.68M
American Depositary Shares Indirect	Ordinary Shares1.82M shares	8/10/2026	S · Sale	+605.17K	16.00	—	5.08M
American Depositary Shares Indirect	Ordinary Shares360K shares	8/10/2026	S · Sale	+120K	16.00	—	4.96M
American Depositary Shares Indirect	Ordinary Shares180K shares	8/10/2026	S · Sale	+60K	16.35	—	4.90M
American Depositary Shares Indirect	Ordinary Shares300K shares	8/10/2026	S · Sale	+100K	16.00	—	4.80M