GREY MICHAEL G

PrivateCIK: 1240122

Location

SAN DIEGO, CA

GREY MICHAEL G

Filed: 12/15/2025ACC: 0001240122-25-000009

InsiderGREY MICHAEL GCIK 1240122

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IssuerSPRUCE BIOSCIENCES, INC.CIK 1683553

DirectorOfficer· Executive Chairman

Since Oct 2020

0.00

Net shares

Net seller

$0.00

Total acquired

0

Open market trades

0B · 0S

12

Total transactions

4.34K acquired · 4.34K disposed

Non-Derivative Transactions0

No non-derivative transactions reported

Derivative Transactions12

Stock Option (Right to Buy)

Direct

A · Award

Converts to

Common Stock

387.00 shares

Shares

+387.00

Strike price

104.13

Held after

387.00

Exercisable

—

12/11/2025

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

387.00 shares

Shares

−387.00

Strike price

108

Held after

0.00

Exercisable

—

12/11/2025

Stock Option (Right to Buy)

Direct

A · Award

Converts to

Common Stock

1.25K shares

Shares

+1.25K

Strike price

104.13

Held after

1.25K

Exercisable

—

12/11/2025

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

1.25K shares

Shares

−1.25K

Strike price

123

Held after

0.00

Exercisable

—

12/11/2025

Stock Option (Right to Buy)

Direct

A · Award

Converts to

Common Stock

1.50K shares

Shares

+1.50K

Strike price

104.13

Held after

1.50K

Exercisable

—

12/11/2025

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

1.50K shares

Shares

−1.50K

Strike price

230.25

Held after

0.00

Exercisable

—

12/11/2025

Stock Option (right to buy)

Direct

A · Award

Converts to

Common Stock

133.00 shares

Shares

+133.00

Strike price

104.13

Held after

133.00

Exercisable

—

12/11/2025

Stock Option (right to buy)

Direct

D · Disposition

Converts to

Common Stock

133.00 shares

Shares

−133.00

Strike price

1143

Held after

0.00

Exercisable

—

12/11/2025

Stock Option (Right to Buy)

Direct

A · Award

Converts to

Common Stock

666.00 shares

Shares

+666.00

Strike price

104.13

Held after

666.00

Exercisable

—

12/11/2025

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

666.00 shares

Shares

−666.00

Strike price

186

Held after

0.00

Exercisable

—

12/11/2025

Stock Option (Right to Buy)

Direct

A · Award

Converts to

Common Stock

400.00 shares

Shares

+400.00

Strike price

104.13

Held after

400.00

Exercisable

—

12/11/2025

Stock Option (Right to Buy)

Direct

D · Disposition

Converts to

Common Stock

400.00 shares

Shares

−400.00

Strike price

169.50

Held after

0.00

Exercisable

—

12/11/2025

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Stock Option (Right to Buy) Direct	Common Stock387.00 shares	12/11/2025	A · Award	+387.00	104.13	—	387.00
Stock Option (Right to Buy) Direct	Common Stock387.00 shares	12/11/2025	D · Disposition	−387.00	108	—	0.00
Stock Option (Right to Buy) Direct	Common Stock1.25K shares	12/11/2025	A · Award	+1.25K	104.13	—	1.25K
Stock Option (Right to Buy) Direct	Common Stock1.25K shares	12/11/2025	D · Disposition	−1.25K	123	—	0.00
Stock Option (Right to Buy) Direct	Common Stock1.50K shares	12/11/2025	A · Award	+1.50K	104.13	—	1.50K
Stock Option (Right to Buy) Direct	Common Stock1.50K shares	12/11/2025	D · Disposition	−1.50K	230.25	—	0.00
Stock Option (right to buy) Direct	Common Stock133.00 shares	12/11/2025	A · Award	+133.00	104.13	—	133.00
Stock Option (right to buy) Direct	Common Stock133.00 shares	12/11/2025	D · Disposition	−133.00	1143	—	0.00
Stock Option (Right to Buy) Direct	Common Stock666.00 shares	12/11/2025	A · Award	+666.00	104.13	—	666.00
Stock Option (Right to Buy) Direct	Common Stock666.00 shares	12/11/2025	D · Disposition	−666.00	186	—	0.00
Stock Option (Right to Buy) Direct	Common Stock400.00 shares	12/11/2025	A · Award	+400.00	104.13	—	400.00
Stock Option (Right to Buy) Direct	Common Stock400.00 shares	12/11/2025	D · Disposition	−400.00	169.50	—	0.00