Filed: 2/17/2026ACC: 0001172661-26-001093
📋 What this filing means
GREAT POINT PARTNERS LLC filed this quarterly 13F‑HR report disclosing 29 equity positions with a total reported market value of $308.41M. This filing provides a transparent view of the manager's long equity holdings as of the quarter end.
29
Positions
$308.41M
Total AUM (reported)
25.36M
Total Shares
Allocation by class
COM$200.74M65.1%
COM NEW$68.06M22.1%
CLASS A ORD SHS$20.00M6.5%
CL A$9.14M3.0%
COM SHS$5.56M1.8%
ADS$4.91M1.6%
Portfolio Concentration
Top 3$69.36M22.5%
4–10$121.91M39.5%
11–25$107.48M34.9%
Rest$9.66M3.1%
Top 3 weight
22.5%
Top 10 weight
62.0%
Voting Authority Distribution
Total shares with voting rights: 25.36M
Sole
Full voting authority
0.00
shares
% of voting shares0.0%
Shared
Joint voting authority
25.36M
shares
% of voting shares100.0%
None
No voting authority
0.00
shares
% of voting shares0.0%
Investment Discretion (by position count)
Sole0
Shared0
Other29
Dominant voting typeShared · 100.0% of voting shares
Institutional Holdings29
Rows:
APOGEE THERAPEUTICS INC
DFNDShares374K
TypeSH
Market value$28.23M
9.15%
Sole
0.00
Shared
374K
None
0.00
AMYLYX PHARMACEUTICALS INC
DFNDShares1.75M
TypeSH
Market value$21.14M
6.85%
Sole
0.00
Shared
1.75M
None
0.00
ZURA BIO LTD
DFNDShares3.82M
TypeSH
Market value$20.00M
6.48%
Sole
0.00
Shared
3.82M
None
0.00
DISC MEDICINE INC
DFNDShares250K
TypeSH
Market value$19.85M
6.44%
Sole
0.00
Shared
250K
None
0.00
RAPT THERAPEUTICS INC
DFNDShares581.19K
TypeSH
Market value$19.68M
6.38%
Sole
0.00
Shared
581.19K
None
0.00
IMMUNOVANT INC
DFNDShares750K
TypeSH
Market value$19.07M
6.18%
Sole
0.00
Shared
750K
None
0.00
SOLENO THERAPEUTICS INC
DFNDShares400K
TypeSH
Market value$18.52M
6.00%
Sole
0.00
Shared
400K
None
0.00
VOR BIOPHARMA INC
DFNDShares1.37M
TypeSH
Market value$17.92M
5.81%
Sole
0.00
Shared
1.37M
None
0.00
DIANTHUS THERAPEUTICS INC
DFNDShares350K
TypeSH
Market value$14.42M
4.68%
Sole
0.00
Shared
350K
None
0.00
JADE BIOSCIENCES INC
DFNDShares806.27K
TypeSH
Market value$12.44M
4.03%
Sole
0.00
Shared
806.27K
None
0.00
KALVISTA PHARMACEUTICALS INC
DFNDShares685.63K
TypeSH
Market value$11.07M
3.59%
Sole
0.00
Shared
685.63K
None
0.00
CONTINEUM THERAPEUTICS INC
DFNDShares800K
TypeSH
Market value$9.14M
2.96%
Sole
0.00
Shared
800K
None
0.00
EUPRAXIA PHARMACEUTICALS INC
DFNDShares1.20M
TypeSH
Market value$9.06M
2.94%
Sole
0.00
Shared
1.20M
None
0.00
FULCRUM THERAPEUTICS INC
DFNDShares800K
TypeSH
Market value$9.05M
2.93%
Sole
0.00
Shared
800K
None
0.00
NEKTAR THERAPEUTICS
DFNDShares210.73K
TypeSH
Market value$8.91M
2.89%
Sole
0.00
Shared
210.73K
None
0.00
UPSTREAM BIO INC
DFNDShares300K
TypeSH
Market value$8.14M
2.64%
Sole
0.00
Shared
300K
None
0.00
NEUROGENE INC
DFNDShares350K
TypeSH
Market value$7.21M
2.34%
Sole
0.00
Shared
350K
None
0.00
ULTRAGENYX PHARMACEUTICAL IN
DFNDShares300K
TypeSH
Market value$6.90M
2.24%
Sole
0.00
Shared
300K
None
0.00
CONTEXT THERAPEUTICS INC
DFNDShares4.68M
TypeSH
Market value$6.89M
2.23%
Sole
0.00
Shared
4.68M
None
0.00
CULLINAN THERAPEUTICS INC
DFNDShares634.03K
TypeSH
Market value$6.56M
2.13%
Sole
0.00
Shared
634.03K
None
0.00
EVOMMUNE INC
DFNDShares325K
TypeSH
Market value$5.56M
1.80%
Sole
0.00
Shared
325K
None
0.00
ORUKA THERAPEUTICS INC
DFNDShares183.33K
TypeSH
Market value$5.56M
1.80%
Sole
0.00
Shared
183.33K
None
0.00
SILENCE THERAPEUTICS PLC
DFNDShares808.03K
TypeSH
Market value$4.91M
1.59%
Sole
0.00
Shared
808.03K
None
0.00
UNICYCIVE THERAPEUTICS INC
DFNDShares796.56K
TypeSH
Market value$4.60M
1.49%
Sole
0.00
Shared
796.56K
None
0.00
CLIMB BIO INC
DFNDShares979.53K
TypeSH
Market value$3.92M
1.27%
Sole
0.00
Shared
979.53K
None
0.00
| Issuer | Class | Shares | Type | Value / Portfolio % | Voting — Sole | Shared | None |
|---|---|---|---|---|---|---|---|
APOGEE THERAPEUTICS INCDFND | COM | 374K | SH | $28.23M 9.15% | 0.00 | 374K | 0.00 |
AMYLYX PHARMACEUTICALS INCDFND | COM | 1.75M | SH | $21.14M 6.85% | 0.00 | 1.75M | 0.00 |
ZURA BIO LTDDFND | CLASS A ORD SHS | 3.82M | SH | $20.00M 6.48% | 0.00 | 3.82M | 0.00 |
DISC MEDICINE INCDFND | COM | 250K | SH | $19.85M 6.44% | 0.00 | 250K | 0.00 |
RAPT THERAPEUTICS INCDFND | COM NEW | 581.19K | SH | $19.68M 6.38% | 0.00 | 581.19K | 0.00 |
IMMUNOVANT INCDFND | COM | 750K | SH | $19.07M 6.18% | 0.00 | 750K | 0.00 |
SOLENO THERAPEUTICS INCDFND | COM | 400K | SH | $18.52M 6.00% | 0.00 | 400K | 0.00 |
VOR BIOPHARMA INCDFND | COM NEW | 1.37M | SH | $17.92M 5.81% | 0.00 | 1.37M | 0.00 |
DIANTHUS THERAPEUTICS INCDFND | COM | 350K | SH | $14.42M 4.68% | 0.00 | 350K | 0.00 |
JADE BIOSCIENCES INCDFND | COM NEW | 806.27K | SH | $12.44M 4.03% | 0.00 | 806.27K | 0.00 |
KALVISTA PHARMACEUTICALS INCDFND | COM | 685.63K | SH | $11.07M 3.59% | 0.00 | 685.63K | 0.00 |
CONTINEUM THERAPEUTICS INCDFND | CL A | 800K | SH | $9.14M 2.96% | 0.00 | 800K | 0.00 |
EUPRAXIA PHARMACEUTICALS INCDFND | COM | 1.20M | SH | $9.06M 2.94% | 0.00 | 1.20M | 0.00 |
FULCRUM THERAPEUTICS INCDFND | COM | 800K | SH | $9.05M 2.93% | 0.00 | 800K | 0.00 |
NEKTAR THERAPEUTICSDFND | COM NEW | 210.73K | SH | $8.91M 2.89% | 0.00 | 210.73K | 0.00 |
UPSTREAM BIO INCDFND | COM | 300K | SH | $8.14M 2.64% | 0.00 | 300K | 0.00 |
NEUROGENE INCDFND | COM | 350K | SH | $7.21M 2.34% | 0.00 | 350K | 0.00 |
ULTRAGENYX PHARMACEUTICAL INDFND | COM | 300K | SH | $6.90M 2.24% | 0.00 | 300K | 0.00 |
CONTEXT THERAPEUTICS INCDFND | COM | 4.68M | SH | $6.89M 2.23% | 0.00 | 4.68M | 0.00 |
CULLINAN THERAPEUTICS INCDFND | COM | 634.03K | SH | $6.56M 2.13% | 0.00 | 634.03K | 0.00 |
EVOMMUNE INCDFND | COM SHS | 325K | SH | $5.56M 1.80% | 0.00 | 325K | 0.00 |
ORUKA THERAPEUTICS INCDFND | COM | 183.33K | SH | $5.56M 1.80% | 0.00 | 183.33K | 0.00 |
SILENCE THERAPEUTICS PLCDFND | ADS | 808.03K | SH | $4.91M 1.59% | 0.00 | 808.03K | 0.00 |
UNICYCIVE THERAPEUTICS INCDFND | COM NEW | 796.56K | SH | $4.60M 1.49% | 0.00 | 796.56K | 0.00 |
CLIMB BIO INCDFND | COM | 979.53K | SH | $3.92M 1.27% | 0.00 | 979.53K | 0.00 |
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