GONCALVES JOANA (Chief Medical Officer) sold 18.1% of their position (7K shares) of ORUKA THERAPEUTICS, INC. on the open market

Open‑market sale worth $523.6K — a significant reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 5 sales

GONCALVES JOANA

Filed: 10/15/2026ACC: 0000907654-26-000108

InsiderGONCALVES JOANACIK 1756991

→

IssuerORUKA THERAPEUTICS, INC.CIK 907654

Officer· Chief Medical Officer

Since Feb 2026

-7K

Net shares

Net seller

$523.6K

Total sold

Open market trades

0B · 5S

Total transactions

7K acquired · 14K disposed

Non-Derivative Transactions7

Common Stock

Direct

M · Option Exercise

+3.50K

Price / share

$6.84

Trade value

$23.94K

% of position

11.0%

10/15/2026

31.77K→35.27K

Common Stock

Direct

M · Option Exercise

+3.50K

Price / share

$7.80

Trade value

$27.30K

% of position

9.9%

10/15/2026

35.27K→38.77K

Common Stock

Direct

S · Sale

−2.85K

Price / share

$73.89

Trade value

$210.81K

% of position

7.4%

10/15/2026

38.77K→35.92K

Common Stock

Direct

S · Sale

−1.85K

Price / share

$74.69

Trade value

$137.96K

% of position

5.1%

10/15/2026

35.92K→34.07K

Common Stock

Direct

S · Sale

−1.40K

Price / share

$75.48

Trade value

$105.68K

% of position

4.1%

10/15/2026

34.07K→32.67K

Common Stock

Direct

S · Sale

−700.00

Price / share

$76.67

Trade value

$53.67K

% of position

2.1%

10/15/2026

32.67K→31.97K

Common Stock

Direct

S · Sale

−200.00

Price / share

$77.71

Trade value

$15.54K

% of position

0.6%

10/15/2026

31.97K→31.77K

Total

Net shares

+0.00

Net value

-$472.41K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	10/15/2026	M · Option Exercise	+3.50K	$6.84	$23.94K	11.0%	31.77K	35.27K
Common Stock Direct	10/15/2026	M · Option Exercise	+3.50K	$7.80	$27.30K	9.9%	35.27K	38.77K
Common Stock Direct	10/15/2026	S · Sale	−2.85K	$73.89	$210.81K	7.4%	38.77K	35.92K
Common Stock Direct	10/15/2026	S · Sale	−1.85K	$74.69	$137.96K	5.1%	35.92K	34.07K
Common Stock Direct	10/15/2026	S · Sale	−1.40K	$75.48	$105.68K	4.1%	34.07K	32.67K
Common Stock Direct	10/15/2026	S · Sale	−700.00	$76.67	$53.67K	2.1%	32.67K	31.97K
Common Stock Direct	10/15/2026	S · Sale	−200.00	$77.71	$15.54K	0.6%	31.97K	31.77K
Total			+0.00		-$472.41K

Derivative Transactions2

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.50K shares

−3.50K

Strike price

6.84

Held after

190.06K

Exercisable

—

10/15/2026

Employee Warrant (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.50K shares

−3.50K

Strike price

7.80

Held after

161.49K

Exercisable

—

10/15/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Employee Stock Option (right to buy) Direct	Common Stock3.50K shares	10/15/2026	M · Option Exercise	−3.50K	6.84	—	190.06K
Employee Warrant (right to buy) Direct	Common Stock3.50K shares	10/15/2026	M · Option Exercise	−3.50K	7.80	—	161.49K