GONCALVES JOANA (Chief Medical Officer) sold 17.6% of their position (7K shares) of ORUKA THERAPEUTICS, INC. on the open market

Open‑market sale worth $603.9K — a significant reduction. Review remaining holdings and any 10b5‑1 plan disclosures.

S · 4 sales

GONCALVES JOANA

Filed: 7/15/2026ACC: 0000907654-26-000073

InsiderGONCALVES JOANACIK 1756991

→

IssuerORUKA THERAPEUTICS, INC.CIK 907654

Officer· Chief Medical Officer

Since Feb 2026

-7K

Net shares

Net seller

$603.9K

Total sold

Open market trades

0B · 4S

Total transactions

7K acquired · 14K disposed

Non-Derivative Transactions6

Common Stock

Direct

M · Option Exercise

+3.50K

Price / share

$6.84

Trade value

$23.94K

% of position

10.7%

7/15/2026

32.72K→36.22K

Common Stock

Direct

M · Option Exercise

+3.50K

Price / share

$7.80

Trade value

$27.30K

% of position

9.7%

7/15/2026

36.22K→39.72K

Common Stock

Direct

S · Sale

−400.00

Price / share

$84.36

Trade value

$33.75K

% of position

1.0%

7/15/2026

39.72K→39.32K

Common Stock

Direct

S · Sale

−2.50K

Price / share

$85.86

Trade value

$214.39K

% of position

6.4%

7/15/2026

39.32K→36.82K

Common Stock

Direct

S · Sale

−3.80K

Price / share

$86.68

Trade value

$329.63K

% of position

10.3%

7/15/2026

36.82K→33.02K

Common Stock

Direct

S · Sale

−300.00

Price / share

$87.25

Trade value

$26.18K

% of position

0.9%

7/15/2026

33.02K→32.72K

Total

Net shares

+0.00

Net value

-$552.70K

Security	Date	Type	Shares	Price / Share	Trade Value	% of Position	Held Before	Held After
Common Stock Direct	7/15/2026	M · Option Exercise	+3.50K	$6.84	$23.94K	10.7%	32.72K	36.22K
Common Stock Direct	7/15/2026	M · Option Exercise	+3.50K	$7.80	$27.30K	9.7%	36.22K	39.72K
Common Stock Direct	7/15/2026	S · Sale	−400.00	$84.36	$33.75K	1.0%	39.72K	39.32K
Common Stock Direct	7/15/2026	S · Sale	−2.50K	$85.86	$214.39K	6.4%	39.32K	36.82K
Common Stock Direct	7/15/2026	S · Sale	−3.80K	$86.68	$329.63K	10.3%	36.82K	33.02K
Common Stock Direct	7/15/2026	S · Sale	−300.00	$87.25	$26.18K	0.9%	33.02K	32.72K
Total			+0.00		-$552.70K

Derivative Transactions2

Employee Stock Option (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.50K shares

−3.50K

Strike price

6.84

Held after

200.56K

Exercisable

—

7/15/2026

Employee Warrant (right to buy)

Direct

M · Option Exercise

Converts to

Common Stock

3.50K shares

−3.50K

Strike price

7.80

Held after

171.99K

Exercisable

—

7/15/2026

Security	Converts To	Date	Type	Shares	Strike Price	Exercisable	Held After
Employee Stock Option (right to buy) Direct	Common Stock3.50K shares	7/15/2026	M · Option Exercise	−3.50K	6.84	—	200.56K
Employee Warrant (right to buy) Direct	Common Stock3.50K shares	7/15/2026	M · Option Exercise	−3.50K	7.80	—	171.99K